RESUMO
There was studied the use of SPECT-CT for visualization of sentinel lymph nodes and lymph drainage pathways in 35 patients with localized prostate cancer (cT1-T2 N0 M0). Sentinel lymph nodes were imaged in 31 (89%) patients. There were advantageously detected drainage pathways to exterior (77%) and internal iliac (58%) lymph nodes. Visceral (29%) lymph nodes (paraprostatic, paravesical and mesorectal) were less determined. There was established high informative value of SPECT-CT for imaging sentinel lymph nodes, determining their location as well as identification of lymph drainage pathways in patients with prostate cancer.
Assuntos
Neoplasias da Próstata/diagnóstico por imagem , Linfonodo Sentinela/diagnóstico por imagem , Tomografia Computadorizada com Tomografia Computadorizada de Emissão de Fóton Único/métodos , Idoso , Humanos , MasculinoRESUMO
The aim of the study was to evaluate clinical value of transperineal saturation biopsy (TPSB) in 52 patients with suspicious for prostate cancer (PCa): 31 - primary patients and 17 - men with non-effective transrectal biopsy. PCa was diagnosed in 31 of 52 (59,6%) patients. Focal lesions revealed in 6 (19,4%), multifocal - in another 25 (80,6%) cases. TPSB is very helpful in primary diagnosis and for therapy planning.
Assuntos
Neoplasias da Próstata/diagnóstico , Neoplasias da Próstata/patologia , Idoso , Biópsia , Humanos , Masculino , Pessoa de Meia-Idade , Neoplasias da Próstata/terapiaRESUMO
This study was performed in order to determine individual variability of axillary sentinel lymph nodes (SLN) localization in patient with breast cancer (BC). Individual topography of axillary SLN was determined in 182 patients with early BC. All women were candidates for conservative surgical treatment with postoperative radiotherapy. SPECT-CT visualization of SLN started 120-240 min after intratumoral injection of 74-150MBq of 99mTc-radiocolloids. Distribution of axillary SLN was allocated to following subregions: central (C), pectoral (P), apical (AP), lateral (L), subscapular (SSc). SLN visualization by SPECT-CT was successful in 153 cases (84%). AP nodes were detected in 7 patients (5%). SLN were localized on thoracic wall in 34 cases (22%), in the intrapectoral region--in 3 (2%) women. According to axillary levels they were detected on level I--in 149 (97%), level II--15 (10%), level III-- (7.5%) cases.
Assuntos
Neoplasias da Mama/diagnóstico , Carcinoma Ductal de Mama/diagnóstico , Linfonodos/patologia , Biópsia de Linfonodo Sentinela , Tomografia Computadorizada de Emissão de Fóton Único , Tomografia Computadorizada por Raios X , Adulto , Idoso , Axila , Neoplasias da Mama/patologia , Carcinoma Ductal de Mama/patologia , Meios de Contraste/administração & dosagem , Feminino , Humanos , Linfonodos/diagnóstico por imagem , Metástase Linfática/diagnóstico , Pessoa de Meia-Idade , Tecnécio/administração & dosagem , Cavidade TorácicaRESUMO
There were analyzed dosimetric plans obtained during the first session of HDR brachytherapy in 70 primary prostate cancer patients. Assessments were subjected to dosimetric parameters (V100, D90, D2cc, D10) obtained after implantation in the prostate needle-intrastats estimated before and after adjustment of contours of the prostate and surrounding organs at risk. It was showed that in most cases they were matched to the intended dosimetric parameters: V100 average--94,1% (V100 more than 90% in 97.2% of cases), D90 average--104,3% (D90 100% achieved in 95.7% of cases). In contrast, when using primary plan dosimetry without estimation of changing the geometry of the prostate and organs at risk in 38.6% patients V100 value was below 80%, in 41.4% patients--was in the range from 80% to 90%. In 24.3% patients index D90 did not exceed 80%, in 31.4% patients determined in the range from 80% to 90% and in 24.3% patients was close to 100%. In the absence of correction of contours of the urethra and the prostate in 18% patients the value of D10 for the urethra was higher border 115% and could increase to critical 189%.
