1.
Bioorg Med Chem Lett
; 17(23): 6576-8, 2007 Dec 01.
Artigo
em Inglês
| MEDLINE
| ID: mdl-17942304
RESUMO
Phosphorothioate oligonucleotide-peptide conjugates were synthesized by solid phase fragment condensation (SPFC). Arginine rich peptides could be successfully conjugated in 2.8-13.4% isolated yields. All the products were fully characterized by reversed phase HPLC and MALDI-TOF-MS to give satisfactory results.