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In Vivo ; 28(1): 121-4, 2014.
Artigo em Inglês | MEDLINE | ID: mdl-24425846

RESUMO

BACKGROUND/AIM: Salivary gland tumors are mostly benign tumors. Whether a more conservative surgical approach at greater risk of recurrence, or a more radical intervention with an increased risk of facial paralysis is warranted is still under discussion. Our study addresses the opportunity for improving surgical outcome by employing platelet-rich plasma (PRP) gel at the surgical site. PATIENTS AND METHODS: Twenty consecutive patients undergoing superficial parotidectomy were randomized and assigned to two groups, one with and one without PRP gel. Many parameters were evaluated after surgery and during follow-up, such as the duration of hospitalization, facial nerve deficit, onset of Frey's syndrome, relapse, cosmetic results, presence of keloid or scar depressions, behavior of several facial muscles. RESULTS: Our explorative analysis suggests a positive effect of PRP on surgical outcome in patients undergoing parotidectomy, whereas no negative effects were detected. CONCLUSION: This work suggests that administration of PRP in patients undergoing parotidectomy is beneficial.


Assuntos
Recidiva Local de Neoplasia/cirurgia , Plasma Rico em Plaquetas/química , Medicina Regenerativa , Neoplasias das Glândulas Salivares/cirurgia , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Géis/química , Géis/uso terapêutico , Humanos , Masculino , Pessoa de Meia-Idade , Recidiva Local de Neoplasia/patologia , Complicações Pós-Operatórias , Neoplasias das Glândulas Salivares/patologia , Resultado do Tratamento
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