[Use of coulometric titration for elucidating the mechanism of the oxidation of 6-APA alkaline breakdown products by halogens]. / Primenenie kulonemetricheskogo titrovaniia dlia vyiavleniia mekhanizma okisleniia produktov shchelochnogo razlozheniia 6-APK galogenami

Penaldinic acid and penicillamine were formed on alkali decomposition (1 N NaOH) of 6-APA for 20 minutes at room temperature, penicillamine being completely oxidized to disulphide by the air oxygen. Coulometric titration of the alkali decomposition products showed that generated chlorine in 0.5 N HCl solution or bromine in a week acid solution of KBr oxidized them with participation of 7 electrones. Generated iodine did not practically oxidize the 6-APA decomposition products during the coulometric titration.