Seroreactivity of Peruvian sheep and goats to small ruminant lentivirus-ovine progressive pneumonia virus.

Sera from 3,369 sheep and 1,394 goats in Peru were examined by agar-gel immunodiffusion for antibodies to ovine progressive pneumonia virus (OPPV). The point prevalence rates for antibodies to OPPV in sheep were 1.7% to 40.6% (mean, 19.02%) in the 7 flocks studied, whereas for goats, the point prevalence rates for antibodies that cross-reacted with OPPV in 12 herds were 0.0% to 45.1%. For sheep, a direct association between increasing age and increasing seroreactivity to OPPV was established, and there was evidence to indicate that lambs born to primiparous ewes and raised separated from all other sheep after they were weaned may have been less likely to become infected with OPPV than those lambs born to multiparous ewes and not separated from other sheep after they were weaned. For goats, antibodies to OPPV were detected in 7 of 12 herds studied, the highest infection rate being present within a herd in the Lima department (district).

Accion del levamisole en la produccion de anticuerpos neutralizantes despues de la vacunacion contra la enfermedad de Newcastle en pollos. / Influence of levamisole in the production of neutralizing antibodies after vaccination against Newcastle disease

Treinta pollos de doce semanas de edad, fueron divididos al azar en tres grupos de diez aves cada uno, se usaron para estudiar el efecto inmunoestimulante del levamisole al aplicarse oralmente despues de una vacunacion ocular contra el virus de Newcastle. Las aves del grupo vacunado y tratado 48 horas despues con levamisole, en dosis de 10mg de droga pura por Kg de peso vivo, presentaron un mayor titulo de anticuerpos neutralizantes, estadisticamente significativo (0.01), que el grupo vacunado al que no se administro levamisole.Ambos grupos resistieron 100% al desavacunados.lento de Newcastle con titulo de 10.8.67 DL50/0.1ml. Los pollos del grupo no vacuno y al cual no se aplico levamisole, no desa rrollaron anticuerpos y sufrieron 100% mortandad. Los resultados demuestran que el levamisole actua como un inmunoestimulante en la tasa de anticuerpos neutralizantes del virus de Newcastle, si se usa 48 horas despues que los pollos han sid