RESUMO
Dogs with periodontitis were used to determine the efficacy of an oral regimen of clindamycin versus chlorhexidine acetate oral rinse in reducing the total number of bacteria and the incidence of bacteremia before and after dental scaling. Aerobic and anaerobic bacteria, isolated from blood and gingival swab cultures, were identified to genus using an automated system.
Assuntos
Antibacterianos/uso terapêutico , Bacteriemia/veterinária , Clorexidina/uso terapêutico , Clindamicina/uso terapêutico , Doenças do Cão/prevenção & controle , Periodontite/veterinária , Administração Oral , Animais , Antibacterianos/administração & dosagem , Bacteriemia/prevenção & controle , Clorexidina/administração & dosagem , Clindamicina/administração & dosagem , Raspagem Dentária/veterinária , Doenças do Cão/cirurgia , Cães , Gengiva/microbiologia , Antissépticos Bucais/administração & dosagem , Antissépticos Bucais/uso terapêutico , Periodontite/prevenção & controle , Cuidados Pré-Operatórios/veterinária , Resultado do TratamentoRESUMO
Periodontal disease is considered the most common disease of dogs and cats. The clinical sign most frequently reported by clients is oral malodor. Clindamycin hydrochloride has been used for several years for the treatment of periodontal disease in both cats and dogs. This study was designed to assess the effect of clindamycin HCl when used in two different post-prophylaxis treatment regimens on oral malodor and periodontal disease in a controlled clinical trial. This study demonstrated that a 5-day postprophylaxis regimen was significantly effective in reducing oral malodor compared with a dental prophylaxis alone. Clindamycin HCl significantly reduced oral malodor from the animals' baseline levels through 42 days. In addition, although no effect was observed on periodontal pocket depth, this treatment regimen also resulted in significant reductions in dental plaque, dental calculus, and gingival bleeding.
