A dataset of urban traffic flow for 13 Romanian cities amid lockdown and after ease of COVID19 related restrictions.

This dataset comprises street-level traces of traffic flow as reported by Here Maps™ for 13 cities of Romania from 15th. of May 2020 and until 5th. of June 2020. This covers the time two days before lifting of the mobility restrictions imposed by the COVID19 nation-wide State of Emergency and until four days after the second wave of relaxation, announced for 1st. of June 2020. Data were sampled at a 15-min interval, consistent with the Here API update time. The data are annotated with relevant political decisions and religious events which might influence the traffic flow. Considering the relative scarcity of real-life traffic data, one can use this data set for micro-simulation during development and validation of Intelligent Transportation Solutions (ITS) algorithms while another facet would be in the area of social and political sciences when discussing the effectiveness and impact of statewide restriction during the COVID19 pandemic.

Clustering drug-drug interaction networks with energy model layouts: community analysis and drug repurposing.

Analyzing drug-drug interactions may unravel previously unknown drug action patterns, leading to the development of new drug discovery tools. We present a new approach to analyzing drug-drug interaction networks, based on clustering and topological community detection techniques that are specific to complex network science. Our methodology uncovers functional drug categories along with the intricate relationships between them. Using modularity-based and energy-model layout community detection algorithms, we link the network clusters to 9 relevant pharmacological properties. Out of the 1141 drugs from the DrugBank 4.1 database, our extensive literature survey and cross-checking with other databases such as Drugs.com, RxList, and DrugBank 4.3 confirm the predicted properties for 85% of the drugs. As such, we argue that network analysis offers a high-level grasp on a wide area of pharmacological aspects, indicating possible unaccounted interactions and missing pharmacological properties that can lead to drug repositioning for the 15% drugs which seem to be inconsistent with the predicted property. Also, by using network centralities, we can rank drugs according to their interaction potential for both simple and complex multi-pathology therapies. Moreover, our clustering approach can be extended for applications such as analyzing drug-target interactions or phenotyping patients in personalized medicine applications.

A high-availability architecture for continuous monitoring of sleep disorders.

We present a complete technical solution for continuously monitoring vital signs required for observing sleep apnoea events, one of the major sleep respiratory disorders. Based on industry accepted medical devices, we developed a GSM-based remote data acquisition and transfer module that is integrated via a set of web services into the server side of the application. The back-end is responsible with aggregating all the data, and, based on machine learning techniques, it provides a first level of filtering in order to warn about possible abnormalities. The proposed solution is currently under the test phase at the "Victor Babes" Hospital in Timisoara, Romania.