RESUMO
A case of von Recklinghausen's disease associated with a somatostatinoma of the pancreas causing obstructive jaundice is described. Discussion on the association of von Recklinghausen's disease with somatostatinoma is presented.
Assuntos
Ampola Hepatopancreática , Colestase/etiologia , Neoplasias do Ducto Colédoco/complicações , Somatostatinoma/complicações , Adulto , Tumor Carcinoide/complicações , Neoplasias Duodenais/complicações , Feminino , Humanos , Neoplasias Pancreáticas/complicaçõesRESUMO
We report a patient with controlled coeliac disease but severe dermatitis herpetiformis who was intolerant of dapsone and sulphapyridine. She ultimately had to be treated with parenteral heparin which brought about involution of the skin lesions with symptomatic relief within 1 week. The mechanism of action of heparin is uncertain but may be related to the inhibition of the formation of proteases generated from polymorphs by the clotting process. The treatment is associated with great difficulties in administration over the long term and associated with the risk of haemorrhage. This case illustrates these problems.
