[Changes in the hormonal content of the blood during chronic electrostimulation of the hypothalamus and amygdaloid complex]. / Izmenenie soderzhaniia gormonov v krovi pri khronicheskoi élektrostimuliatsii gipotalamusa i mindalevidnogo kompleksa.

The changes of corticotropin, thyrotropin in hypophysis, triiodothyronine, thyroxin in thyroid gland, adrenaline, norepinephrine, hydrocortisone, 11-OKS in adrenal glands and pancreas, caused by prolonged electrostimulation of hypothalamic ventro-median nucleus, lateral nucleus of amygdala and the combination of the latter with the SP injection, were studied in chronic experiments on rabbits. The electrostimulation increased the hormone contents in the blood, whereas glucagon contents as well as norepinephrine contents was decreasing in stimulation of hypothalamus and amygdala, resp. The SP injection against the background of electrostimulation of the amygdala resulted in the hormone status standardisation.

[Hormonal homeostasis and intraocular pressure in chronic emotional stress caused by influences acting on the amygdala]. / Gormonal'nyi gomeostaz i vnutriglaznoe davlenie pri khronicheskom émotsional'nom stresse, vyzvannom vozdeìstviiami na mindalevidnyi kompleks.

Changes in intraocular pressure, eye hydrodynamics and the amount of hypophyseal, thyroid, adrenal and pancreatic hormones were studied during continuous stimulation of amygdaloid complex or after administration of angiotensin II into the structure in rabbits. The effects involved changes in hormonal homeostasis and elevation of intraocular pressure due to a hypersecretion of intraocular fluid. The administration of angiotensin II during the amygdala stimulation enhanced the changes.

[Changes in collagen metabolism during the chronic electrical stimulation of the midbrain reticular formation]. / Izmeneniia obmena kollagena pri khronicheskoi élektricheskoi stimuliatsii retikuliarnoi formatsii srednego mozga.

The content of 11-hydroxycorticosteroids, free and bound hydroxyproline in the peripheral blood, as well as the level of free and net hydroxyproline in the aortic wall and myocardium of rabbits were studied in chronic prolonged electrical stimulation of the mesencephalon reticular system. The experiments have shown that electrical stimulation leads to the activation of adrenal cortex function and is accompanied by alterations in collagen metabolism, accumulation of collagen in the aorta and decreased collagen level in the myocardium.

[Collagen metabolism in chronic electrical stimulation of the amygdaloid complex]. / Obmen kollagena pri khronicheskoi élektricheskoi stimuliatsii mindalevidnogo kompleksa.

The content of adrenaline, noradrenaline, 11-hydroxycorticosteroids, free and bound hydroxyproline in the peripheral blood of rabbits and collagen metabolism in the aortal wall were studied under chronic electrostimulation of the amygdaloid complex. Electrostimulation of the lateral nucleus of the amygdaloid was shown to induce definite shifts in the content of adrenocortical hormones and leads to collagen metabolism activation that results in collagen accumulation by the aortal wall.

[Hemodynamic changes upon nociceptive stimulation and stimulation of the amygdaloid complex following catecholamine administration]. / Izmenenie gemodinamiki pri notsitseptivnom razdrazhenii i stimuliatsii mindalevidnogo kompleksa posle vvedeniia katekholaminov.

In cats, changes in arterial pressure (AP), intracardiac pressure (ICP), and blood flow volume rate following a nociceptive stimulus, stimulation of the amygdala and the combination of these before and after adrenaline (A) and norepinephrine (NE) administration into the lateral nucleus of amygdala, were studied. Nociceptive stimuli and electric stimulation of amygdala increased AP and ICP. The combination of these increased the pressor reaction. The blood flow volume rate was not altered by the nociceptive stimulus while decreasing at amygdalar stimulation. After A and NE administration the stimulation of amygdala plus the nociceptive stimulus suppressed the pressor reaction; a nociceptive stimulus was followed by the same changes as in intact cats; a nociceptive stimulus plus the stimulation of the amygdala increased the pressor reaction. The blood flow volume rate response to the stimuli was the same as in the control group. But the stimulation of amygdala after NE and a nociceptive stimulus plus amygdala stimulation (20 min after A) increased the blood flow volume rate, while the stimulation of amygdala alone with A administration reduced the blood flow.

[Hemodynamics during combined nociceptive stimulation and stimulation of the amygdaloid complex following treatment of the sensomotor cortex]. / Gemodinamika pri sochetanii notsitseptivnogo razdrazheniia i stimuliatsii mindalevidnogo kompleksa posle vozdeistviia na sensomotornuiu oblast' kory.

In acute experiments on cats, changes of the arterial pressue (AP), intracardiac pressure (ICP), and of the blood flow rate following a nociceptive stimulus (NS), electrical stimulation of the lateral nucleus of amygdala (AL), and the combination of these stimuli before and after application of strychnine and potassium chloride on sensorimotor cortical area, were studied. After the application of strychnine and potassium chloride, the stimulation of AL produced weaker pressor reaction; while a nociceptive stimulus was followed by the same changes as in the intact cats. After the application of strychnine, combination of the AL stimulation and NS produced the increase of pressor reaction; while after the application of potassium chloride, the pressor reaction did not change at all or became weaker. After the application of strychnine, the blood flow rate response to the stimuli was similar to the control experiments; after the application of potassium chloride the blood flow rate decreased.

[Hemodynamic reactions in response to simultaneous nociceptive and amygdalar influences following stimulation and removal of the cervical sympathetic nerves]. / Gemodinamicheskaia reaktsiia v otvet na sovmestnye notsiteseptivnye i amigdaliarnye vliianiia pri razdrazhenii i udalenii sheinykh simpaticheskikh nervov

In cats, nociceptive stimulation and stimulation of amygdala elicited pressor reaction which was much more obvious at the combination of these stimuli. In sympathectomized animals, these stimuli produced a weaker pressor reaction. Combination of sympathetic nerve stimulation with the nociceptive stimulation and stimulation of amygdaloid complex elicited different reactions depending on the order of stimulation. After sympathectomy, separate stimulations produced a decrease of the blood flow rate; the same was obtained after combination of stimulation of the amygdaloid complex with nociceptive stimuli; however, complex effects also depended on the order of stimuli.