[The dynamics of alteration of liquors' proteins under malignant neoplasms].

The article presents the results of analysis of lymph and blood in 78 patients with breast cancer of I, II. III and IV stages. The content of total protein, albumins, globulins and fibrinogens was detected to study the protein balance in biological liquors under various stages of cancer. The results testify that in oncological patients it is essential to detect protein content of blood and peripheral lymph with subsequent adjustment.

[Morphological peculiarities of the adipose tissue and their significance for the ultrasound lipodestruction].

Using the autopsy material obtained from 20 human corpses, the samples of subcutaneous adipose tissue of the gluteal, abdominal, inguino-ileal and axillar areas, as well as the samples of mesenterial, retroperitoneal, mediastinal, pararectal and paranephral adipose tissue was studied histologically. The average sizes of the lobes and of adipocytes were measured, and the degree of the development of connective tissue elements was determined. Adipose tissue was found to have a similar general structural plan in all the areas studied, however the differences were noted in the thickness of the interlobular connective tissue septae and in tissue vascularization. The gluteal, inguino-ileal and anterior abdominal wall adipose tissue had the highest density. The lobules of this adipose tissue possessed the minimal numbers of adipocytes that had the smallest size. The mediastinal, retroperitoneal and paranephral adipose tissue was classified as a relatively loose one. The velocity of lipodestruction depended the degree of the development of connective tissue septae: this process proceed most rapidly in the mediastinal adipose tissue and most slowly--in the gluteal adipose tissue. In all the other areas studied, the duration of lipodestruction was the intermediate one.

[Liposonodestruction in spleen-saving operations in abdominal oncology].

Based on an analysis of morphological investigations the authors have shown distinctions of the adipose tissue in different topographic-anatomical areas of man. It was found that destruction of fat with an apparatus of sonolipodestruction takes different time. This technology was most efficient when used in operations on organs of the abdominal cavity, in mobilization of the spleen. In combined operations for gastric cancer the technology with sonolipodestruction allows mobilization of the spleen and 10, 11 groups of lymph nodes in obese patients with minimal complications. The technology described improves results of surgical operations in gastric cancer.

[Assessment of immediate and intermediate results of surgery for gastrointestinal tumors with hepatic metastasis].

The paper discusses the results of treatment of 316 patients with gastro-intestinal tumors metastasizing to the liver. Patients were divided into 3 groups by tumor localization (stomach, colon, rectum). The best results were reported in patients who had had cytoreductive surgery for primary tumor, radiofrequency ablation and chemotherapy (42). All patients of that group survived over 12 months.

[High-intensity ultrasonic destruction of fatty tissue in the course of lymphatic dissection in oncological patients].

The paper discusses experimental findings in support of ultrasound destruction of fat tissue at different sites. Rate of destruction was designed to match that of development of the connective-tissue stroma of adipose tissue and size of adipose cells. Parameters of adipose tissue framework at different sites may be taken into account during extended lymph node dissection using ultrasound liposuction in oncological practice.

[Validation and approaches to correction of hemorheologic disorders in patients with gastrointestinal cancer]. / Obosnovanie i puti korrektsii gemoreologicheskikh rasstroistv u bol'nykh rakom zheludochno-kishechnogo trakta.

A total of 237 patients were examined: 127 with gastric cancer and 110 with colonic cancer, 99 women and 138 men, mean age 57.5 years. Erythrocyte deformability and aggregation were studied by original methods. Red blood, protein metabolism, and endogenous intoxication parameters were evaluated by routine laboratory tests. Increased aggregation and volume of erythrocytes and decrease of their deformability and hemoglobin content in parallel with hypo- and dysproteinemia and increased level of endogenous intoxication were observed in all patients with gastrointestinal cancer. Correction of these disorders by intravenous laser exposure of the blood essentially improved the erythron status and protein metabolism and decreased endotoxicosis. Infusion/transfusion therapy also notably improved the erythron function and decreased endogenous intoxication. Analysis of the results of surgery showed decreased incidence of complications and lethal outcomes, which was due to methods of corrective therapy.