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Eur Rev Med Pharmacol Sci ; 28(9): 3439-3446, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38766800

RESUMO

OBJECTIVE: Due to infectious complications of transrectal prostate biopsy (TRBx), the transperineal prostate biopsy (TPBx) technique is gaining popularity and is the first-line method in many institutions. We share our experience of the first 100 patients with TPBx, performed using the coaxial needle technique under local anesthesia. PATIENTS AND METHODS: We retrospectively reviewed the records of the first 100 patients who had undergone TPBx between December 2022 and September 2023. Complication rates, cancer detection rates, patient tolerance, and pain response to the TPBx under local anesthesia at different steps of the procedure were collected. RESULTS: The mean age, total prostate-specific antigen (PSA), prostate volume, and PSA density were 64.5±7.5 years, 8.82±12 ng/mL, 58.4±26.4 mL, and 0.17±0.18 ng/mL2. Prostate cancer (PCa) was detected at histopathological evaluation in 51 patients. The mean positive core number and percentage of cancer involvement per core in patients who have PCa were 5.4±3.2 and 68.5±29.1, respectively. The mean pain score during the entire procedure was 2.85±1.48. When the steps are evaluated separately, the mean pain score during the probe placement step, local anesthetic, and sampling steps were 3.35±1.65, 2.54±1.45, and 0.9±0.82, respectively. CONCLUSIONS: Transperineal prostate biopsy with coaxial needle technique under local anesthesia is a well-tolerated procedure with feasible complication rates and patient discomfort.


Assuntos
Anestesia Local , Próstata , Neoplasias da Próstata , Humanos , Masculino , Pessoa de Meia-Idade , Anestesia Local/efeitos adversos , Anestesia Local/métodos , Estudos Retrospectivos , Idoso , Neoplasias da Próstata/patologia , Próstata/patologia , Períneo , Antígeno Prostático Específico/sangue , Biópsia por Agulha/efeitos adversos , Biópsia por Agulha/métodos
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