[Proliferation and differentiation of hematopoietic stem cells during tumor growth]. / Proliferatsiia i differentsirovka gemopoéticheskikh stvolovykh kletok pri opukholevom roste.

The influence of transplantable tumour on migration, proliferation and differentiation of haemopoietic stem cells was studied. It is shown that in the initial period of tumour development the migration and proliferation of stem cells intensify. In the final stage of the tumour growth the quantity of haemopoietic stem cells decreases considerably in the bone marrow, spleen, and peripheral blood. It is established that during the tumour growth the differentiation of stem cells from the spleen changed towards erythropoiesis.

[Mechanism of immunosuppression in carcinogenesis. I. Contact interaction of macrophages with T-lymphocytes in the dynamics of tumor growth]. / Mekhanizm immunosupressii pri kantserogeneze. Soobshchenie I. Kontaktnoe vzaimodeistvie makrofagov s T-limfotsitami v dinamike opukholevogo rosta.

The suppression of the "grape-forming" activity of macrophages has been shown to occur in the process of the development of tumor growth under the conditions of in vitro culture, which seems to be one of the important factors ensuring the "deficit" state in the population of mature lymphocytes.