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1.
Phys Rev E ; 109(4): L042102, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38755819

RESUMO

Two-dimensional (2D) Kardar-Parisi-Zhang (KPZ) growth is usually investigated on substrates of lateral sizes L_{x}=L_{y}, so that L_{x} and the correlation length (ξ) are the only relevant lengths determining the scaling behavior. However, in cylindrical geometry, as well as in flat rectangular substrates L_{x}≠L_{y} and, thus, the surfaces can become correlated in a single direction, when ξ∼L_{x}≪L_{y}. From extensive simulations of several KPZ models, we demonstrate that this yields a dimensional crossover in their dynamics, with the roughness scaling as W∼t^{ß_{2D}} for t≪t_{c} and W∼t^{ß_{1D}} for t≫t_{c}, where t_{c}∼L_{x}^{1/z_{2D}}. The height distributions (HDs) also cross over from the 2D flat (cylindrical) HD to the asymptotic Tracy-Widom Gaussian orthogonal ensemble (Gaussian unitary ensemble) distribution. Moreover, 2D to one-dimensional (1D) crossovers are found also in the asymptotic growth velocity and in the steady-state regime of flat systems, where a family of universal HDs exists, interpolating between the 2D and 1D ones as L_{y}/L_{x} increases. Importantly, the crossover scalings are fully determined and indicate a possible way to solve 2D KPZ models.

2.
Phys Rev E ; 107(6-1): 064140, 2023 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-37464689

RESUMO

While the one-point height distributions (HDs) and two-point covariances of (2+1) Kardar-Parisi-Zhang (KPZ) systems have been investigated in several recent works for flat and spherical geometries, for the cylindrical one the HD was analyzed for few models and nothing is known about the spatial and temporal covariances. Here, we report results for these quantities, obtained from extensive numerical simulations of discrete KPZ models, for three different setups yielding cylindrical growth. Beyond demonstrating the universality of the HD and covariances, our results reveal other interesting features of this geometry. For example, the spatial covariances measured along the longitudinal and azimuthal directions are different, with the former being quite similar to the curve for flat (2+1) KPZ systems, while the latter resembles the Airy_{2} covariance of circular (1+1) KPZ interfaces. We also argue (and present numerical evidence) that, in general, the rescaled temporal covariance A(t/t_{0}) decays asymptotically as A(x)∼x^{-λ[over ¯]} with an exponent λ[over ¯]=ß+d^{*}/z, where d^{*} is the number of interface sides kept fixed during the growth (being d^{*}=1 for the systems analyzed here). Overall, these results complete the picture of the main statistics for the (2+1) KPZ class.

3.
Environ Sci Pollut Res Int ; 30(18): 53862-53875, 2023 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-36864333

RESUMO

The demands upon the arid area for water supply pose threats to both the quantity and quality of social and economic activities. Thus, a widely used machine learning model, namely the support vector machines (SVM) integrated with water quality indices (WQI), was used to assess the groundwater quality. The predictive ability of the SVM model was assessed using a field dataset for groundwater from Abu-Sweir and Abu-Hammad, Ismalia, Egypt. Multiple water quality parameters were chosen as independent variables to build the model. The results revealed that the permissible and unsuitable class values range from 36 to 27%, 45 to 36%, and 68 to 15% for the WQI approach, SVM method and SVM-WQI model respectively. Besides, the SVM-WQI model shows a low percentage of the area for excellent class compared to the SVM model and WQI. The SVM model trained with all predictors with a mean square error (MSE) of 0.002 and 0.41; the models that had higher accuracy reached 0.88. Moreover, the study highlighted that SVM-WQI can be successfully implemented for the assessment of groundwater quality (0.90 accuracy). The resulting groundwater model in the study sites indicates that the groundwater is influenced by rock-water interaction and the effect of leaching and dissolution. Overall, the integrated ML model and WQI give an understanding of water quality assessment, which may be helpful in the future development of such areas.


Assuntos
Água Subterrânea , Poluentes Químicos da Água , Qualidade da Água , Monitoramento Ambiental/métodos , Abastecimento de Água , Aprendizado de Máquina , Poluentes Químicos da Água/análise
4.
Phys Rev E ; 108(6-1): 064802, 2023 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-38243503

RESUMO

We perform kinetic Monte Carlo simulations of film growth in simple cubic lattices with solid-on-solid conditions, Ehrlich-Schwoebel (ES) barriers at step edges, and a kinetic barrier related to the hidden off-plane diffusion at multilayer steps. Broad ranges of the diffusion-to-deposition ratio R, detachment probability per lateral neighbor, ε, and monolayer step crossing probability P=exp[-E_{ES}/(k_{B}T)] are studied. Without the ES barrier, four possible scaling regimes are shown as the coverage θ increases: nearly layer-by-layer growth with damped roughness oscillations; kinetic roughening in the Villain-Lai-Das Sarma (VLDS) universality class when the roughness is W∼1 (in lattice units); unstable roughening with mound nucleation and growth, where slopes of logW×logθ plots reach values larger than 0.5; and asymptotic statistical growth with W=θ^{1/2} solely due to the kinetic barrier at multilayer steps. If the ES barrier is present, the layer-by-layer growth crosses over directly to the unstable regime, with no transient VLDS scaling. However, in simulations up to θ=10^{4} (typical of films with a few micrometers), low temperatures (small R, Îµ, or P) may suppress the two or three initial regimes, while high temperatures and P∼1 produce smooth surfaces at all thicknesses. These crossovers help to explain proposals of nonuniversal exponents in previous works. We define a smooth film thickness θ_{c} where W=1 and show that VLDS scaling at that point indicates negligible ES barriers, while rapidly increasing roughness indicates a small ES barrier (E_{ES}∼k_{B}T). θ_{c} scales as ∼exp(const×P^{2/3}) if the other parameters are kept fixed, which represents a high sensitivity on the ES barrier. The analysis of recent experimental data in the light of our results distinguishes cases where E_{ES}/(k_{B}T) is negligible, ∼1, or ≪1.

5.
Phys Chem Chem Phys ; 24(45): 27856-27865, 2022 Nov 23.
Artigo em Inglês | MEDLINE | ID: mdl-36367016

RESUMO

We study a thin-film electrodeposition model that represents the relaxation of the deposited material by adatom diffusion on quenched crystal topographies and considers simple mechanisms of cation flux in the electrolyte. The results of numerical simulations with collimated flux and a rapid cation reduction in contact with the deposit relate the surface roughness and the adatom hop numbers with two model parameters. A comparison with the results of a collective diffusion model for vapor deposition shows differences in the surface morphologies but similarities in scaling relations, which suggest thermally activated (Arrhenius) forms for the parameters of the electrodeposition model and relate one of them to the applied current. Simulations with purely diffusive cation flux and possible pore formation in simple cubic lattices show the growth of self-organized structures with leaf shapes (dendrites) above a compact layer that covers the flat electrode. The thickness of this layer and the average dendrite size also obey scaling relations in terms of the model parameters, which predict that both sizes decrease with the applied current, in agreement with recent experimental studies. Under all flux conditions, an increase in adatom diffusivity with temperature implies an increase in the average sizes of low-energy surface configurations, independently of their particular shapes. Finally, we note that a previously proposed model for electrodeposition produced similar morphologies, but the quantitative relations for the characteristic sizes differ from those of the present model, which also advances with a consistent interpretation of temperature effects.

6.
Phys Rev E ; 105(5-1): 054804, 2022 May.
Artigo em Inglês | MEDLINE | ID: mdl-35706246

RESUMO

Fundamental properties of an interface evolving on a domain of size L, such as its height distribution (HD) and two-point covariances, are known to assume universal but different forms depending on whether L is fixed (flat geometry) or expands linearly in time (radial growth). The interesting situation where L varies nonlinearly, however, is far less explored and it has never been tackled for two-dimensional (2D) interfaces. Here, we study discrete Kardar-Parisi-Zhang (KPZ) growth models deposited on square lattice substrates, whose (average) lateral size enlarges as L=L_{0}+ωt^{γ}. Our numerical simulations reveal that the competition between the substrate expansion and the increase of the correlation length parallel to the substrate, ξ≃ct^{1/z}, gives rise to a number of interesting results. For instance, when γ<1/z the interface becomes fully correlated, but its squared roughness, W_{2}, keeps increasing as W_{2}∼t^{2αγ}, as previously observed for one-dimensional (1D) systems. A careful analysis of this scaling, accounting for an intrinsic width on it, allows us to estimate the roughness exponent of the 2D KPZ class as α=0.387(1), which is very accurate and robust, once it was obtained averaging the exponents for different models and growth conditions (i.e., for various γ^{'}s and ω^{'}s). In this correlated regime, the HDs and covariances are consistent with those expected for the steady-state regime of the 2D KPZ class for flat geometry. For γ≈1/z, we find a family of distributions and covariances continuously interpolating between those for the steady-state and the growth regime of radial KPZ interfaces, as the ratio ω/c augments. When γ>1/z the system stays forever in the growth regime and the HDs always converge to the same asymptotic distribution, which is the one for the radial case. The spatial covariances, on the other hand, are (γ,ω)-dependent, showing a trend towards the covariance of a random deposition in enlarging substrates as the expansion rate increases. These results considerably generalize our understanding of the height fluctuations in 2D KPZ systems, revealing a scenario very similar to the one previously found in the 1D case.

7.
Clin Res Hepatol Gastroenterol ; 46(5): 101900, 2022 05.
Artigo em Inglês | MEDLINE | ID: mdl-35259498

RESUMO

INTRODUCTION: Two subtypes of fecal incontinence (FI) are defined in the literature (urge and passive FI). The pertinence of this classification is unknown due to conflicting findings and heterogeneity of definitions. However, no questionnaire is available to clearly classify patients among subtypes. The objective of the present study was to develop and validate a new tool (Fecal incontinence subtype assessment, FI-SA) in order to better classify patients among the different subtypes of FI. METHODS: A prospective monocentric study was conducted in consecutive patients with FI according to Rome IV criteria. To validate psychometric properties of the FI-SA questionnaire, a literature review and qualitative interviews were performed and discussed with an expert panel. A feasibility study was realized to assess acceptability and comprehension of items. The reproducibility was investigated in a validation study. RESULTS: Comprehension and acceptability were excellent in 90% of patients in the feasibility study (n = 30). Validation study (n = 100) showed a good reproducibility with an intra-class correlation coefficient of 0.91 and 0.89 for questions 1 and 2. Time to fill the questionnaire was 40.0 s. 98.0% patients were classified among subtypes of FI: 34.0% passive FI, 32.0% urge FI and 32.0% mixed FI. CONCLUSION: FI-SA is the first questionnaire to classify patients among subtypes of FI with good psychometric characteristics and the first questionnaire introducing the concept of mixed FI. FI-SA could help to determine the pertinence of this classification of FI in the management of these patients.


Assuntos
Incontinência Fecal , Incontinência Fecal/diagnóstico , Humanos , Estudos Prospectivos , Reprodutibilidade dos Testes , Inquéritos e Questionários
8.
Ann R Coll Surg Engl ; 103(9): 666-672, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-34432532

RESUMO

BACKGROUND: The worldwide COVID-19 pandemic has led to the popularisation of 'virtual' clinics. In orthopaedics, little is known about the use of virtual clinics within foot and ankle surgery, specifically. METHODS: A cross-sectional observation study of patients and clinicians in response to virtual clinics in foot and ankle surgery. Patients seen in a virtual clinic were contacted by telephone from two weeks after their consultation and asked to complete a 12-point questionnaire. Demographic information was also collected. Clinicians in foot and ankle completed a 10-point questionnaire. RESULTS: One hundred patient responses were collected. Patient satisfaction with virtual clinics was positive, with 65% of respondents reporting they were very happy (Likert scale rating 5). More than 90% of patients felt they received enough information, felt involved, felt the virtual clinic was helpful and knew who to contact if there was a problem. However, 79% would still prefer a face-to-face consultation, and 22% would have preferred a video consultation. Clinician responses were more cautious, with 60% stating they were neither happy nor unhappy (Likert scale rating 3). Virtual clinics may be faster for the clinician. CONCLUSIONS: Virtual clinics may be more convenient for patients, with high satisfaction levels reported, but represent significant clinical challenges for foot and ankle surgeons. Elements of virtual clinics may persist post pandemic, particularly in routine follow-up. Virtual clinics are not appropriate for new patient referrals.


Assuntos
Tornozelo/cirurgia , Atitude do Pessoal de Saúde , Atitude Frente a Saúde , COVID-19 , Pé/cirurgia , Ortopedia , Satisfação do Paciente , Telemedicina , Adulto , Idoso , Estudos Transversais , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Autorrelato
9.
Saudi Med J ; 42(6): 589-611, 2021 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-34078721

RESUMO

Extracorporeal membrane oxygenation (ECMO) is considered as a supportive treatment that provides circulatory and ventilatory support and can be thought off as a bridge to organ recovery. Since 2009, it has been applied as a rescue treatment for patients with severe adult respiratory distress syndrome (ARDS) mainly due to viral causes. In December 2019, several patients presented with a constellation of symptoms of viral pneumonia in China. A new strain of the corona virus family, called COVID-19, has been discovered to be the cause of this severe mysterious illness that was named severe acute respiratory syndrome coronavirus 2 (SARS­CoV­2). This new virus continued to spread across the globe leading to the World Health Organization announcing it as a pandemic in the early 2020. By the end of March 2021, the number of COVID-19 cases worldwide exceeded 126 million cases. In Saudi Arabia, the first confirmed case of COVID-19 was reported in the 2nd March 2020. By the end of March 2021, the total number of confirmed COVID-19 cases in Saudi Arabia is just above 360,000. In anticipation of the need of ECMO for the treatment of patients with SARS­CoV­2 based on the previous Middle East respiratory syndrome coronavirus pandemic experience, the Saudi Extra-Corporeal Life Support (ECLS) chapter that is under the umbrella of the Saudi Critical Care Society (SCCS) convened a working group of ECMO experts. The mission of this group was to formulate a guidance for the use of ECMO as a last resort for patients with severe ARDS, especially with COVID-19 based on available evidence. The ECLS-SCCS chapter wanted to generate a document that can be used to simple guide, with a focus on safety, to provide ECMO service for patients with severe ARDS with a special focus on SARS­CoV­2.


Assuntos
COVID-19/terapia , Oxigenação por Membrana Extracorpórea/métodos , Pneumonia Viral/terapia , Pneumonia Viral/virologia , Síndrome do Desconforto Respiratório/terapia , Adulto , Animais , COVID-19/virologia , Humanos , SARS-CoV-2/isolamento & purificação , Arábia Saudita
10.
Prog Urol ; 31(12): 732-738, 2021 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-33941463

RESUMO

AIMS: The aim of this study was to define the prevalence of comorbidities among multiple sclerosis patients with lower urinary tract symptoms. METHODS: A retrospective study of data collected prospectively from January 2000 to March 2016 was carried out using a database. Comorbidities were divided into several classes according to the International Classification of Diseases (ICD-10). RESULTS: One hundred and fifty-five patients were included. All had a neurogenic bladder with 150 (96%) overactive bladder. EDSS score was≥6 in 44 patients (28%). Comorbidities were present in 79 (50,9%) and the most frequent ones were cardiovascular (14,2%), endocrinological (10,3%), urological (8,4%), abdominal (7,7%). Overweight (BMI≥25) was observed in 63 (40%). A strict relationship was found for BMI and stress urinary incontinence (P<0.001) as well as voiding dysfunction (P=0.003) without significant association for BMI and overactive bladder. CONCLUSION: Prevalence of comorbidities is important in MS (more than 50%). A significant association is found between overweight, stress urinary incontinence and voiding dysfunction. Knowledge of these comorbidities in MS is important since the presence of these urinary symptoms not related to neurogenic bladder must lead to a specific treatment. LEVEL OF EVIDENCE: 3.


Assuntos
Esclerose Múltipla , Bexiga Urinaria Neurogênica , Bexiga Urinária Hiperativa , Humanos , Esclerose Múltipla/complicações , Esclerose Múltipla/epidemiologia , Prevalência , Estudos Retrospectivos , Bexiga Urinaria Neurogênica/complicações , Bexiga Urinaria Neurogênica/epidemiologia , Bexiga Urinária Hiperativa/epidemiologia
11.
Phys Rev E ; 103(2-1): 022138, 2021 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-33736020

RESUMO

The infiltration of a solute in a fractal porous medium is usually anomalous, but chemical reactions of the solute and that material may increase the porosity and affect the evolution of the infiltration. We study this problem in two- and three-dimensional lattices with randomly distributed porous sites at the critical percolation thresholds and with a border in contact with a reservoir of an aggressive solute. The solute infiltrates that medium by diffusion and the reactions with the impermeable sites produce new porous sites with a probability r, which is proportional to the ratio of reaction and diffusion rates at the scale of a lattice site. Numerical simulations for r≪1 show initial subdiffusive scaling and long time Fickean scaling of the infiltrated volumes or areas, but with an intermediate regime with time increasing rates of infiltration and reaction. The anomalous exponent of the initial regime agrees with a relation previously applied to infinitely ramified fractals. We develop a scaling approach that explains the subsequent time increase of the infiltration rate, the dependence of this rate on r, and the crossover to the Fickean regime. The exponents of the scaling relations depend on the fractal dimensions of the critical percolation clusters and on the dimensions of random walks in those clusters. The time increase of the reaction rate is also justified by that reasoning. As r decreases, there is an increase in the number of time decades of the intermediate regime, which suggests that the time increasing rates are more likely to be observed is slowly reacting systems.

12.
Prog Urol ; 31(4): 231-237, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33414018

RESUMO

PURPOSE: The aim of this study was to describe verbal instructions used to obtain a voluntary pelvic floor muscle contraction and to evaluate their understanding and acceptability. METHODS: This prospective study led in two phases. A questionnaire was submitted to experts to collect the most frequently used instructions to obtain a PFMC. Then a questionnaire was submitted to subjects in order to: estimate the pelvic floor anatomical knowledge; estimate understanding and acceptability of these instructions; select the best instruction. RESULTS: First phase: 46 experts proposed 356 instructions. Forty-four percent were functional instructions ("hold a gas"), 40% anatomical ("squeeze your anus") and 16% allied both. Fifteen instructions for the women and 11 for the men were selected. Second phase: 33 subjects completed the questionnaire. More than 75% had correct answers for anatomical knowledge. The instructions judged by the subjects as the most adapted to obtain a PFMC were: "contract the anus", "do as if you wanted to hold a strong desire to void". The items including "perineum" or "vagina" were less understood. CONCLUSIONS: The more understandable and acceptable instruction to assess the PFMC is the association of two simple instructions: one anatomical and one functional. LEVEL OF EVIDENCE: 4.


Assuntos
Compreensão , Conhecimentos, Atitudes e Prática em Saúde , Contração Muscular , Diafragma da Pelve/fisiologia , Adulto , Idoso , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Educação de Pacientes como Assunto , Estudos Prospectivos , Inquéritos e Questionários
13.
Prog Urol ; 31(3): 169-174, 2021 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-33309471

RESUMO

OBJECTIVE: To assess the reproducibility of detrusor activity cystometric pattern in multiple sclerosis (MS) patients, which is poorly documented in the medical literature, by means of successive filling. METHODS: We conducted a prospective study in MS patients; cystometry was repeated twice at 5minutes of interval if a detrusor overactivity before 300mL of filling was observed. Thus, 3 successive cystometries were analysed. The following characteristics were recorded: detrusor maximum pressure (Pmax), volume at the first involuntary detrusor contraction (IDC), maximum cystometric capacity (MCC), pressure at the first IDC, the existence of an overactive detrusor classified as phasic or terminal. RESULTS: We included 31 patients (19 women and 12 men); only 6 patients were naïve-treatment, the mean EDSS was: 5.3 (±1.6) and the mean age was 48.4 (±12.5) years. All the patients had an overactive detrusor for each cystometry. The reproducibility was good for all the parameters (range ICC between 0.7 and 0.83). CONCLUSION: Quantitative and qualitative cystometric data have a good reproducibility in MS patients with detrusor overactivity before 300mL of filling. LEVEL OF PROOF: 3.


Assuntos
Esclerose Múltipla/fisiopatologia , Bexiga Urinária/fisiopatologia , Adulto , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Estudos Prospectivos , Reprodutibilidade dos Testes
14.
Phys Rev E ; 102(1-1): 012805, 2020 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-32794924

RESUMO

We study the statistics of the number of executed hops of adatoms at the surface of films grown with the Clarke-Vvedensky (CV) model in simple cubic lattices. The distributions of this number N are determined in films with average thicknesses close to 50 and 100 monolayers for a broad range of values of the diffusion-to-deposition ratio R and of the probability ε that lowers the diffusion coefficient for each lateral neighbor. The mobility of subsurface atoms and the energy barriers for crossing step edges are neglected. Simulations show that the adatoms execute uncorrelated diffusion during the time in which they move on the film surface. In a low temperature regime, typically with Rε≲1, the attachment to lateral neighbors is almost irreversible, the average number of hops scales as 〈N〉∼R^{0.38±0.01}, and the distribution of that number decays approximately as exp[-(N/〈N〉)^{0.80±0.07}]. Similar decay is observed in simulations of random walks in a plane with randomly distributed absorbing traps and the estimated relation between 〈N〉 and the density of terrace steps is similar to that observed in the trapping problem, which provides a conceptual explanation of that regime. As the temperature increases, 〈N〉 crosses over to another regime when Rε^{3.0±0.3}∼1, which indicates high mobility of all adatoms at terrace borders. The distributions P(N) change to simple exponential decays, due to the constant probability for an adatom to become immobile after being covered by a new deposited layer. At higher temperatures, the surfaces become very smooth and 〈N〉∼Rε^{1.85±0.15}, which is explained by an analogy with submonolayer growth. Thus, the statistics of adatom hops on growing film surfaces is related to universal and nonuniversal features of the growth model and with properties of trapping models if the hopping time is limited by the landscape and not by the deposition of other layers.

15.
Am J Case Rep ; 21: e924678, 2020 Jul 08.
Artigo em Inglês | MEDLINE | ID: mdl-32687487

RESUMO

BACKGROUND Vertical diplopia that follows local anesthesia is usually due to inferior rectus muscle fibrosis. Here, we report a rare case of acquired Brown syndrome following local anesthesia. CASE REPORT A 36-year-old woman underwent right inferior orbital fat decompression under local anesthesia. On the first postoperative day, she developed vertical diplopia. She had left hypertropia, which increased on left gaze, with limitation of elevation of the right eye on attempted adduction. Forced duction test of the right eye revealed resistance on elevation in adduction. Magnetic resonance imaging showed signal alteration, thickening, and irregularity involving the right superior oblique tendon and trochlea region. The diagnosis of iatrogenic Brown syndrome was made. Then, a single dose of 10 mg triamcinolone injection was given near the intratrochlear region. On follow-up, complete resolution of diplopia on primary gaze occurred 12 weeks after the incident. CONCLUSIONS The reported case highlights that local anesthesia carries a risk of Brown syndrome. We believe bupivacaine-induced superior oblique hypertrophy is the underlying mechanism. The patient showed excellent outcome after medical management, with no surgical intervention required after 3 months of follow-up.


Assuntos
Tecido Adiposo/cirurgia , Anestesia Local/efeitos adversos , Bupivacaína/efeitos adversos , Descompressão Cirúrgica , Estrabismo/induzido quimicamente , Adulto , Feminino , Humanos
16.
Prog Urol ; 30(11): 588-596, 2020 Sep.
Artigo em Francês | MEDLINE | ID: mdl-32636059

RESUMO

INTRODUCTION: The anal tone allows the maintenance of anorectal continence. Its regulation depends on spinal segmental mechanisms under supra-sacral control. MATERIAL AND METHODS: A systematic review was performed using Medline database, according to PRISMA methodology, using following keywords anal tone ; anal sphincter ; anorectal function ; reflex ; digital rectal examination. RESULTS: Anal hypertonia is an increase in the muscle's resistance to passive stretching. Muscular hypotonia is a decrease in muscle tone. It is associated with a decrease in resistance to passive mobilization. It is not possible to quantify the prevalence of anal tone alterations in the general population and in specific pathological conditions (urinary disorders, neurogenic or non-neurogenic anorectal disorders). In case of hypotonia, most often due to a lower motor neuron lesion, fecal incontinence may occur. Hypertonia (anal sphincter overactivity) is not always due to perineal spasticity. Indeed, in the majority of the cases, the cause of this anal hypertonia in a neurologic context, can be secondary to an upper motor neuron disease due to spinal or encephalic lesion, leading to recto-anal dyssynergia, giving distal constipation. In another way, this anal hypertonia can be purely behavioral, with no direct pathological significance. The evaluation of anal tone is clinical with validated scores but whose sensitivity is not absolute, and instrumental with, on the one hand, the measurement of anal pressure in manometry and, on the other hand, electrophysiological testing which still require validation in this indication. CONCLUSION: Anal tone assessment is of interest in clinical practice because it gives diagnostic arguments for the neurological lesion and its level, in the presence of urinary or anorectal symptoms.


Assuntos
Canal Anal/fisiologia , Tono Muscular , Humanos
17.
Prog Urol ; 30(11): 604-609, 2020 Sep.
Artigo em Francês | MEDLINE | ID: mdl-32434663

RESUMO

OBJECTIVE: Cortical somatosensory evoked potentials (SEP) are usually used to test the integrity of lemniscal pathways and thus provide arguments for the neurogenic etiology of sensory symptoms. For example, PES by perineal stimulation (SEP-P) has been shown to be altered in incontinence or neurogenic sexual dysfunction. We wanted to verify the integrity, structure and amplitude of far-field responses of PES-P in two conditions, the first without feeling the need to urinate (S0), the second with urgency (US). METHODS: SEP-P were recorded in ten patients without neurological pathology in both conditions S0 and US after stimulation of the dorsal nerve of the penis/clitoris. Three consecutive responses each averaged over 1000 passages at a frequency of 3Hz were recorded. RESULTS: Seven men and 3 women were included. All patients had normal SEP-P in terms of amplitude and latency of the P40 complex and fully reproducible especially for late responses. These early P40 responses were identical in both S0 and US states. Conversely, the far-field potentials, i.e. the late responses, were different in the two states, with a significant decrease (P<0.008 paired T-test) in the amplitude of cortical responses in the US state. CONCLUSION: We observe that the late components of SEP-P were altered by the need to urinate urgently with sustained and selective attention to this need. These late components of SEP-P could be useful to better specify the attentional mechanisms involved in the continence-voiding cycle and to specify pathological sensory dysfunctions (urgency, painful bladder, frequency…). LEVEL OF EVIDENCE: 4.


Assuntos
Atenção , Córtex Cerebral/fisiologia , Potenciais Somatossensoriais Evocados , Micção/fisiologia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade
18.
Rev. Asoc. Esp. Espec. Med. Trab ; 28(1): 28-37, mar. 2019. tab
Artigo em Espanhol | IBECS | ID: ibc-185823

RESUMO

Objetivo principal: establecer un sistema de trabajo para la detección y codificación de lesiones músculo-esqueléticas que afectan a trabajadores usuarios de PVD. Material y Métodos: durante el año 2017 se realizó un estudio observacional transversal sobre 427 usuarios de PVD. Se utilizó principalmente el protocolo de PVD del Ministerio de Sanidad, Consumo y Bienestar Social, trasladando los datos obtenidos al programa estadístico SPSS para su procesamiento y estudio a través de una Chi cuadrado. Resultados: existe relación estadísticamente significativa entre lesiones osteomusculares y cuatro variables: 1) Horas de exposición diaria a PVD. 2) Lateralidad manual. 3) Edad. 4) Formación en Prevención de Riesgos Laborales. Conclusiones: mediante la sistematización y estudio de una serie de variables, podemos mejorar la orientación de los hábitos saludables (fundamentalmente posturales) de los trabajadores


Objective: to establish a working system for the detection and codification of musculoskeletal injuries that affect Data Display Screen users. Material and Methods: during the year 2017, a cross-sectional observational study was conducted on 427 Data Display Screen workers. The Data Display Screen protocol of the Ministry of Health, Consumption and Social Welfare was used, transferring the obtained data to the statistical program SPSS for processing through a Chi-squared Results: statistically significant relationship among musculoskeletal injuries and four variables: 1) Hours per day with exposure to Data Display Screen. 2) Manual laterality. 3) Age. 4) Training in Occupational Risk Prevention. Conclusions: through the systematization and study of a series of variables, we can improve the orientation of healthy habits (fundamentally postural) of workers


Assuntos
Humanos , Masculino , Feminino , Pessoa de Meia-Idade , Doenças Musculares/etiologia , Doenças Musculares/epidemiologia , Enfermagem do Trabalho/estatística & dados numéricos , Terminais de Computador , Fatores de Risco , Espanha/epidemiologia , Inquéritos e Questionários , Estudos Transversais
19.
Prog Urol ; 28(11): 542-547, 2018 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-30017704

RESUMO

INTRODUCTION: To assess the feasibility and the accuracy of emptying cystometry in order to simplify the manometric follow-up of overactive detrusor in neurological patients under anticholinergic or botulinum toxin injections. MATERIAL: Female patients with a stable detrusor underwent both a conventional cystometry and sequential measurements of bladder pressure during emptying (emptying cystometry). At the end of the standard cystometry, a CH12 urinary catheter was introduced in the bladder and was connected to a three-way stopcock. The second way of the stopcock permitted the emptying. The third way of the stopcock was connected to a vertical graduated tube to measure the bladder pressure each 50mL during the bladder emptying. RESULTS: Eleven female patients were included (mean age: 59.4years). Nine patients (82%) had neurogenic bladder. Mean cystometric capacity was 439mL (SD: 35mL). During the emptying cystometry, 8 to 10 measures were taken (mean: 9.4). The mean detrusor pressure was 1.7cmH2O (SD 2.1) for the filling cystometry and 2.3cmH2O (SD: 2.7) for the emptying cystometry. The agreement between the detrusor pressure between the two cystometries was good with intra-class correlation coefficient at 0.66 [0.48-0.77] - and the correlation was high (r=0.7; P<0.000001). CONCLUSION: In a small, selected sample of patients, emptying cystometry provides similar results of detrusor pressure to filling cystometry. This technique could constitute a home monitoring of bladder pressures in a selected population of patients with intermittent catheterization in whom a manometric follow-up of detrusor overactivity is required. LEVEL OF EVIDENCE: 4.


Assuntos
Manometria/métodos , Bexiga Urinária Hiperativa/diagnóstico , Bexiga Urinária/fisiopatologia , Adulto , Idoso , Estudos de Viabilidade , Feminino , Humanos , Pessoa de Meia-Idade , Projetos Piloto , Pressão , Estudos Prospectivos , Cateterismo Urinário/métodos , Urodinâmica/fisiologia
20.
Eur Geriatr Med ; 9(2): 249-253, 2018 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-34654250

RESUMO

INTRODUCTION: The main objective of this retrospective study is to determine the efficacy of transcutaneous posterior tibial nerve stimulation (TPTNS) in older patients with overactive bladder (OAB) syndrome. The secondary objective is to look for predictive factors of efficacy of this treatment. METHODS: All patients aged over 65 years with OAB syndrome for which TPTNS was introduced between 2010 and 2016 in two neuro-urology centers were included. Age, gender, etiology of OAB, urinary symptoms and detrusor overactivity (DO) were retrospectively collected. The main outcome was efficacy of TPTNS (i.e., purchase of the device between 3 and 6 months). RESULTS: A total of 264 patients were included (mean age 74.1 ± 6.5 years; 63.3% of women), of whom 53% had neurogenic OAB. Urinary incontinence was reported by 83.7% of patients and DO was found on urodynamic studies in 154 patients. The overall efficacy of TPTNS was 45.1%. None of the tested factors were significantly predictive of efficacy, especially age (≥ 75 years, p = 0.62), associated stress urinary incontinence (p = 0.69) and presence of DO (p = 0.60), whether neurogenic or not. CONCLUSION: TPTNS is an effective treatment in older patients with OAB syndrome. No predictive factors of efficacy were found, especially age and DO. This treatment seems to be a good alternative to antimuscarinics against overactive bladder in older adults.

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