Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis.

INTRODUCTION AND IMPORTANCE: Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2-10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduction abnormalities. CASE PRESENTATION: In this article we present a clinical case of a 52-year-old female patient with Bekhterev's disease, who underwent aortic valve reconstruction with autopericardium and mitral homograft implantation in mitral position. CLINICAL DISCUSSION: The use of homografts and reconstructive surgeries using autologous materials allow not only avoiding lifelong intake of anticoagulants, but also maintaining hemodynamic profile comparable to that of native valves. CONCLUSION: This clinical case shows that treatment of patients with rheumatic diseases is a complex treatment problem that requires a personalized approach.

[Resection of recurrent hemangioma of the anterior mediastinum with aortic arch replacement and simultaneous resection of left atrial myxoma]. / Rezektsiya retsidiviruyushchei gemangiomy perednego sredosteniya s protezirovaniem dugi aorty i odnomomentnym udaleniem miksomy levogo predserdiya.

Patients with anterior mediastinum tumors fall into a difficult category due to high risk of invasion of vital structures and complexity of surgical correction. We report resection of recurrent hemangioma of anterior mediastinum with aortic arch replacement and simultaneous resection of left atrial myxoma in a 35-year-old woman. Successful treatment of these patients correlates with aggressive surgical approach followed by total resection of tumor and all affected vessels and other tissues.