[Glutaminase and glutamate decarboxylase activity of brain tissue during hypothermia and hibernation]. / Glutaminaznaia i glutamatdekarboksilaznaia aktivnosti tkani mozga pri gipotermii i zimner spiachke.

A forced cooling of rats and gophers decreases the brain glutaminase activity activated with phosphate with the incubation temperature. The cooling of rats leads to a decrease in the brain glutamate decarboxylase activity. However in the animals cooled down to 20 degrees C the incubation temperature (25 and 20 degrees C) does not affect it. The beginning of hibernation is accompanied by an increase in glutamate decarboxylase activity of the brain, a month later it lowers as compared with the hibernation beginning. The glutaminase activity falls during hibernation. At the hibernation beginning the activating effect of phosphate on the brain glutaminase is reduced, a week later it is intensified and by the end of a month period it is decreased again.