Assuntos
Antirreumáticos/toxicidade , Artrite Reumatoide/tratamento farmacológico , Resistência a Múltiplos Medicamentos/efeitos dos fármacos , Imunoconjugados/uso terapêutico , Abatacepte , Adulto , Ensaios de Uso Compassivo , Substituição de Medicamentos , Feminino , Custos de Cuidados de Saúde , Humanos , Recidiva , Falha de Tratamento , Resultado do Tratamento , Adulto JovemRESUMO
The NEO Personality Inventory was given to 33 married patients with bipolar disorder. Consistent with previous findings, patients with bipolar disorder did not show an abnormal personality profile as a group. Extremely wide variation on all scales indicated that the group profile tells little about individual patients. Trait neuroticism robustly predicted psychiatric symptoms at entry to the study when assessed retrospectively for the two years prior to entry and when averaged over a year of treatment. Neuroticism also negatively predicted the self-confidence of the patients in this sample. The patients identified as outliers on neuroticism form a clinically difficult group for whom the distinction between Axes I and II appears to be less meaningful.
