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1.
Jpn J Radiol ; 42(7): 720-730, 2024 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-38503998

RESUMO

PURPOSE: This study aimed to enhance the diagnostic accuracy of contrast-enhanced breast magnetic resonance imaging (MRI) using gadobutrol for differentiating benign breast lesions from malignant ones. Moreover, this study sought to address the limitations of current imaging techniques and criteria based on the Breast Imaging Reporting and Data System (BI-RADS). MATERIALS AND METHODS: In a multicenter retrospective study conducted in Japan, 200 women were included, comprising 100 with benign lesions and 100 with malignant lesions, all classified under BI-RADS categories 3 and 4. The MRI protocol included 3D fast gradient echo T1- weighted images with fat suppression, with gadobutrol as the contrast agent. The analysis involved evaluating patient and lesion characteristics, including age, size, location, fibroglandular tissue, background parenchymal enhancement (BPE), signal intensity, and the findings of mass and non-mass enhancement. In this study, univariate and multivariate logistic regression analyses were performed, along with decision tree analysis, to identify significant predictors for the classification of lesions. RESULTS: Differences in lesion characteristics were identified, which may influence malignancy risk. The multivariate logistic regression model revealed age, lesion location, shape, and signal intensity as significant predictors of malignancy. Decision tree analysis identified additional diagnostic factors, including lesion margin and BPE level. The decision tree models demonstrated high diagnostic accuracy, with the logistic regression model showing an area under the curve of 0.925 for masses and 0.829 for non-mass enhancements. CONCLUSION: This study underscores the importance of integrating patient age, lesion location, and BPE level into the BI-RADS criteria to improve the differentiation between benign and malignant breast lesions. This approach could minimize unnecessary biopsies and enhance clinical decision-making in breast cancer diagnostics, highlighting the effectiveness of gadobutrol in breast MRI evaluations.


Assuntos
Neoplasias da Mama , Meios de Contraste , Imageamento por Ressonância Magnética , Compostos Organometálicos , Humanos , Feminino , Neoplasias da Mama/diagnóstico por imagem , Imageamento por Ressonância Magnética/métodos , Pessoa de Meia-Idade , Estudos Retrospectivos , Adulto , Idoso , Diagnóstico Diferencial , Mama/diagnóstico por imagem , Japão , Idoso de 80 Anos ou mais , Aumento da Imagem/métodos , Sensibilidade e Especificidade , Imageamento Tridimensional/métodos , Reprodutibilidade dos Testes
2.
Hered Cancer Clin Pract ; 21(1): 23, 2023 Nov 13.
Artigo em Inglês | MEDLINE | ID: mdl-37957733

RESUMO

BACKGROUND: In Japan, genetic testing, surveillance, and risk-reducing surgery for hereditary breast and ovarian cancer (HBOC) syndrome have been covered by the Japanese national insurance system since April 2020. On the other hand, the current situation is that medical care, including surveillance of undiagnosed (cancer-free) patients, is self-funded even for individuals with HBOC. We report a case in which breast cancer was diagnosed at an early stage during surveillance for cancer-free HBOC at the patient's own expense, and risk-reducing surgery was performed at the same time as treatment for breast cancer. CASE PRESENTATION: The patient was a 63-year-old woman. Her sister had a history of breast cancer in her 30s and was found to be a BRCA2 pathogenic variant carrier by genetic testing. The patient therefore presented to the genetic department of our hospital and underwent genetic testing (out-of-pocket). A pathogenic variant was found at the same site. During annual breast and ovarian surveillance at the patient's own expense, a physician with sufficient expertise in contrast-enhanced breast magnetic resonance imaging (MRI) noticed a change in the contrast enhancement pattern on breast MRI and performed needle biopsy, revealing ductal carcinoma in situ. At the request of the patient, she underwent concurrent contralateral risk-reducing mastectomy and risk-reducing salpingo-oophorectomy in addition to breast cancer treatment. CONCLUSIONS: We encountered a case in which cancer treatment and risk-reducing surgery were performed at the same time for a pathogenic variant carrier who was very anxious about developing cancer. Surveillance of cancer-free BRCA1/2 mutation carriers and expansion of insurance coverage for surgery are important future issues.

3.
Mod Rheumatol ; 25(6): 837-41, 2015.
Artigo em Inglês | MEDLINE | ID: mdl-25867232

RESUMO

OBJECTIVE: To explore the clinical application of automated scanning of wrist and finger joints by an Automated Breast Volume Scanner (ABVS) in patients with rheumatoid arthritis (RA). METHODS: A total of 140 metacarpophalangeal (MCP) joints and 28 wrist joints from the 14 active RA patients were examined by both an ABVS system (the ACUSON S2000) from dorsal sites and by conventional ultrasonography (US) from multiple directions on the same day. We used a semiquantitative scale from 0 to 3 of synovial hypertrophy and the presence of bone erosion by grayscale for both methods; the efficacy of the two methods for identifying synovial hypertrophy and bone erosion were evaluated by kappa coefficient. RESULTS: The scanning time of the ABVS was 2 min per patient and that of conventional US was 15 min per patient. The kappa coefficients of synovial hypertrophy in the MCP joints were 0.60 and 0.79 in wrist joints. These values were increased in the joints where synovial hypertrophy was moderate to severe (scores greater than 2). The kappa coefficients for the presence of bone erosion in the MCP joints were 0.74 and 0.93 in wrist joints. CONCLUSION: The present data showed a substantial agreement between ABVS and conventional US for assessments of the synovial hypertrophy and bone erosion of wrist and finger joints in patients with RA. Since ABVS can scan the wrist and finger joints automatically in a short time, ABVS is a helpful new ultrasonic method to examine joint injuries in patients with RA.


Assuntos
Artrite Reumatoide/diagnóstico por imagem , Articulação Metacarpofalângica/diagnóstico por imagem , Membrana Sinovial/diagnóstico por imagem , Articulação do Punho/diagnóstico por imagem , Adulto , Idoso , Idoso de 80 Anos ou mais , Feminino , Humanos , Pessoa de Meia-Idade , Índice de Gravidade de Doença , Ultrassonografia
5.
Jpn J Radiol ; 32(9): 552-5, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-24838832

RESUMO

Exophytic papillary growth from the surface epithelium is one of the features suggesting serous surface borderline tumors of the ovary in which magnetic resonance imaging (MRI) typically shows a hyperintense papillary mass with a hypointense internal branching structure on T2-weighted images. We herein report a case of an endocervical-like mucinous borderline tumor of the ovary, which showed an exophytic papillary growth pattern on MRI as well as pathology. Such a growth pattern is known to be characteristic of serous borderline tumors, but it should be noted that it could also be a finding in mucinous borderline tumors.


Assuntos
Imageamento por Ressonância Magnética/métodos , Neoplasias Ovarianas/diagnóstico , Ovário/patologia , Adulto , Diagnóstico Diferencial , Feminino , Humanos , Neoplasias Ovarianas/cirurgia , Ovário/cirurgia , Adulto Jovem
6.
Abdom Imaging ; 37(2): 239-43, 2012 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-21416130

RESUMO

The patient is a 20-year-old man with glycogen storage disease type I (GSD-type I). In his teens, multiple focal hepatic masses were detected on abdominal ultrasonography (US), which were diagnosed as multiple hepatocellular adenomas from the imaging. During follow-up, these masses had shown intermittent growth in size. In the evaluation of Gd-EOB-DTPA (gadolinium-ethoxybenzyl-diethylenetriamine penta-acetic acid) MR imaging, these masses showed various signal intensities from hypo- to hyperintense during the hepatocyte-specific phase. Intermittent growth and elevation of serum PIVKA-II levels indicate the potential for malignant transformation, so the patient underwent partial hepatectomy. The resected masses were all consistent with benign hepatocellular adenomas histopathologically.


Assuntos
Adenoma de Células Hepáticas/patologia , Meios de Contraste , Gadolínio DTPA , Doença de Depósito de Glicogênio Tipo I/complicações , Neoplasias Hepáticas/patologia , Imageamento por Ressonância Magnética/métodos , Adenoma de Células Hepáticas/etiologia , Adenoma de Células Hepáticas/cirurgia , Hepatectomia/métodos , Humanos , Neoplasias Hepáticas/etiologia , Neoplasias Hepáticas/cirurgia , Masculino , Adulto Jovem
7.
Magn Reson Med Sci ; 10(2): 133-7, 2011.
Artigo em Inglês | MEDLINE | ID: mdl-21720116

RESUMO

We correlate findings from magnetic resonance (MR) imaging and pathology in a 55-year-old woman with spindle cell carcinoma of the breast. Pathological examination showed a fibrous capsule at the margins and abundant fibromyxoid stroma within the mass. Spindle cell carcinoma may be included in the differential diagnosis of expanding round masses with internal components that demonstrate rapid initial enhancement with high signal intensity on T(2)-weighted images in postmenopausal women.


Assuntos
Neoplasias da Mama/diagnóstico , Carcinoma/diagnóstico , Neoplasias da Mama/patologia , Neoplasias da Mama/cirurgia , Carcinoma/patologia , Carcinoma/cirurgia , Meios de Contraste , Diagnóstico Diferencial , Feminino , Gadolínio DTPA , Humanos , Imageamento por Ressonância Magnética/métodos , Pessoa de Meia-Idade
8.
Magn Reson Med Sci ; 9(4): 217-25, 2010.
Artigo em Inglês | MEDLINE | ID: mdl-21187691

RESUMO

We assessed the usefulness and limitations of utilizing apparent diffusion coefficient (ADC) values on diffusion-weighted imaging (DWI) for the differential diagnosis of benign and malignant non-mass-like breast lesions. We retrospectively reviewed 27 such lesions (16 malignant, 11 benign) detected on magnetic resonance (MR) imaging and analyzed the enhancing patterns of dynamic contrast-enhanced DCE-MRI (distribution and internal enhancement), kinetic curve patterns, and ADC values. All images were obtained with a 1.5-tesla MR unit, with patients supine. On DCE-MRI, malignant lesions tended to show either segmental or branching-ductal distribution, and when lesions with these patterns were considered malignant, sensitivity was 68.8%; specificity, 63.6%; positive predictive value (PPV), 73.3%; negative predictive value (NPV), 58.3%; and accuracy, 66.7%. Kinetic curve analysis did not reliably differentiate benign and malignant non-mass-like lesions. There was no significant difference between the mean ADC value of the malignant lesions, 0.968 × 10(-3) mm(2)/s at b=1000 s/mm(2), and that of benign lesions, 1.207 × 10(-3) mm(2)/s (P=0.109). Receiver operating characteristic (ROC) analysis revealed the most effective threshold of ADC value for differentiating tumors as 1.1 × 10(-3) mm(2)/s; values lower than this were observed more often in malignant than benign lesions (P=0.054). Us of this threshold yielded sensitivity of 68.8%; specificity, 72.7%; PPV, 78.6%; NPV, 61.5%; and accuracy, 70.4%. Combining the ADC value criteria with the analysis of DCE-MRI pattern increased sensitivity to 93.8%, negative predictive value (NPV) to 85.7%, and accuracy to 77.8% but decreased specificity to 54.5%. Use of ADC values does not adequately improve DCE-MRI performance for differential diagnosis of non-mass-like breast lesions, but adding the ADC value criteria to the DCE-MRI pattern analysis improves sensitivity, NPV, and accuracy.


Assuntos
Neoplasias da Mama/patologia , Carcinoma Ductal de Mama/patologia , Carcinoma Intraductal não Infiltrante/patologia , Imagem de Difusão por Ressonância Magnética/métodos , Adulto , Idoso , Idoso de 80 Anos ou mais , Mama/patologia , Doenças Mamárias/patologia , Meios de Contraste , Diagnóstico Diferencial , Feminino , Seguimentos , Gadolínio DTPA , Humanos , Aumento da Imagem/métodos , Pessoa de Meia-Idade , Variações Dependentes do Observador , Valor Preditivo dos Testes , Curva ROC , Reprodutibilidade dos Testes , Estudos Retrospectivos , Sensibilidade e Especificidade
9.
J Hepatobiliary Pancreat Sci ; 17(6): 831-8, 2010 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-20734206

RESUMO

BACKGROUND: A fragile or non-fibrotic pancreas increases the risk of postoperative pancreatic fistula (POPF) after pancreatic head resection, whereas pancreatic fibrosis decreases the risk. The degree of pancreatic fibrosis can be estimated using the time-signal intensity curve (TIC) of the pancreas, obtained with dynamic magnetic resonance imaging (MRI). We have investigated whether trainee surgeons can perform pancreatic anastomosis safely, without the occurrence of POPF, when patients are selected carefully based on a preoperative assessment of pancreatic fibrosis. METHODS: Seventy-two consecutive patients who underwent pancreatic head resection were enrolled in this prospective trial. Dynamic contrast-enhanced MRI of the pancreas was performed preoperatively in all patients who, based on their pancreatic TIC profile, were then allocated to one of two groups: Group A comprised patients with type I pancreatic TIC, signifying a normal pancreas without fibrosis (n = 46); Group B comprised patients with type II or III pancreatic TIC, signifying a fibrotic pancreas (n = 26). An end-to-side duct-to-mucosa pancreaticojejunostomy was performed in all patients, with all patients in Group A operated on by two experienced surgeons, and all patients in Group B operated on by one of eight trainee surgeons at various stages of training. RESULTS: There was no operative mortality. POPF developed in 19 patients: 12 patients with grade A POPF and seven with grade B. All except one of the POPF occurred in Group A patients. The POPF in the one patient from Group B was grade A (p < 0.001). CONCLUSIONS: A trainee surgeon can perform a secure pancreatic anastomosis without the occurrence of POPF in patients with a pancreas displaying a fibrotic pancreatic TIC on dynamic MRI scans.


Assuntos
Educação Médica Continuada , Pâncreas/patologia , Pancreatectomia/educação , Pancreatopatias/cirurgia , Pancreaticoduodenectomia/educação , Pancreaticojejunostomia/educação , Adulto , Idoso , Idoso de 80 Anos ou mais , Anastomose Cirúrgica/educação , Anastomose Cirúrgica/métodos , Feminino , Fibrose/diagnóstico , Fibrose/cirurgia , Seguimentos , Humanos , Mucosa Intestinal/cirurgia , Imageamento por Ressonância Magnética , Masculino , Pessoa de Meia-Idade , Pâncreas/cirurgia , Pancreatectomia/métodos , Pancreatopatias/patologia , Ductos Pancreáticos/cirurgia , Pancreaticoduodenectomia/métodos , Pancreaticojejunostomia/métodos , Estudos Prospectivos , Resultado do Tratamento
10.
J Surg Res ; 158(1): 61-8, 2010 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-19215944

RESUMO

BACKGROUND: The time-signal intensity curve (TIC) of the pancreas obtained from dynamic contrast-enhanced magnetic resonance imaging closely reflects the histological degree of pancreatic fibrosis. MATERIALS AND METHODS: Seventy-six patients who had undergone a pancreatic TIC analysis prior to receiving a pancreaticoduodenectomy for various reasons were subjected to a yearly monitoring with pancreatic TIC for the pancreatic remnants. The pancreatic TIC profiles were classified into 3 types: type I, indicating a normal pancreas without fibrosis; and types II and III indicating fibrotic pancreas. RESULTS: The preoperative pancreatic TICs were type-I in 51 patients, type-II in 20, and type-III in 5, and the corresponding pancreatic fibrosis ratios were proved histologically to be 4.1%, 13.3%, and 21.2%, respectively. The mean postoperative follow-up period was 40.2 mo. A type-I changed to type-II in 16 patients, by 32.3 mo after surgery. In these patients, the exocrine remnant pancreatic function was preserved at the time of TIC conversion, but it significantly deteriorated thereafter. Pancreatic anastomotic leakage was found to be a significant risk factor predisposing a patient to undergo postoperative TIC conversion. In contrast, a preoperative type-II or III showed a postoperative conversion to type-I or II in 6 patients. In this group, the exocrine pancreatic function was noted to show a good recovery. In 35 patients who had a type-I TIC throughout the study, the remnant pancreatic function was well maintained. CONCLUSIONS: Pancreatic TIC analysis has the ability to detect an early fibrotic change that precedes a functional deterioration of the pancreatic remnant after a pancreaticoduodenectomy. Following a pancreaticoduodenectomy, some patients show an improvement in pancreatic fibrosis, but they may also experience remnant pancreatic fibrosis when pancreatic anastomotic leakage occurs after surgery.


Assuntos
Imageamento por Ressonância Magnética/métodos , Pâncreas/patologia , Pancreaticoduodenectomia/efeitos adversos , Adulto , Idoso , Idoso de 80 Anos ou mais , Anastomose Cirúrgica/efeitos adversos , Feminino , Fibrose , Humanos , Masculino , Pessoa de Meia-Idade
11.
Clin Imaging ; 33(2): 146-9, 2009.
Artigo em Inglês | MEDLINE | ID: mdl-19237061

RESUMO

We report the clinical findings in a 36-year-old woman with diabetic mastopathy. The lesion showed heterogeneous segmental enhancement on magnetic resonance imaging (MRI), resembling a malignant lesion, but diffusion-weighted imaging (DWI) showed no abnormalities and the apparent diffusion coefficient value did not decrease. This case emphasizes the utility of DWI for differentiating diabetic mastopathy from malignant breast lesions. The value of DWI lies in its ability to exclude the possibility of malignant breast lesions and thus to avoid unnecessary biopsy.


Assuntos
Doenças Mamárias/diagnóstico , Diabetes Mellitus Tipo 1/complicações , Imagem de Difusão por Ressonância Magnética , Adulto , Doenças Mamárias/complicações , Neoplasias da Mama/diagnóstico , Diagnóstico Diferencial , Feminino , Humanos , Mamografia , Ultrassonografia Mamária
12.
Bangladesh Med Res Counc Bull ; 34(2): 44-7, 2008 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-19119538

RESUMO

A retrospective study was conducted to demonstrate the potential role of dynamic contrast enhanced magnetic resonance imaging (DCEMRI) in the detection of breast lesions in 15 patients with nipple discharge. The DCEMRI findings were compared and correlated with the findings of ultrasonography and mammography. The results revealed that the character of the nipple discharge was mostly bloody and in few cases were serous. The imaging findings revealed that DCEMRI is highly sensitive and specific in the detection of breast canner and the histopathological correlation in such detection was highly significant (p < 0.001) as compared to ultrasonography and mammography finding.


Assuntos
Doenças Mamárias/diagnóstico , Imageamento por Ressonância Magnética , Mamilos/metabolismo , Adulto , Idoso , Doenças Mamárias/diagnóstico por imagem , Meios de Contraste , Feminino , Humanos , Pessoa de Meia-Idade , Mamilos/diagnóstico por imagem , Estudos Retrospectivos , Ultrassonografia , Adulto Jovem
13.
World J Gastroenterol ; 13(6): 858-65, 2007 Feb 14.
Artigo em Inglês | MEDLINE | ID: mdl-17352014

RESUMO

AIM: To evaluate the ability of the time-signal intensity curve (TIC) of the pancreas obtained from dynamic contrast-enhanced magnetic resonance imaging (MRI) for differentiation of focal pancreatic masses, especially pancreatic carcinoma coexisting with chronic pancreatitis and tumor-forming pancreatitis. METHODS: Forty-eight consecutive patients who underwent surgery for a focal pancreatic mass, including pancreatic ductal carcinoma (n=33), tumor-forming pancreatitis (n=8), and islet cell tumor (n=7), were reviewed. Five pancreatic carcinomas coexisted with longstanding chronic pancreatitis. The pancreatic TICs were obtained from the pancreatic mass and the pancreatic parenchyma both proximal and distal to the mass lesion in each patient, prior to surgery, and were classified into 4 types according to the time to a peak: 25 s and 1, 2, and 3 min after the bolus injection of contrast material, namely, type-I, II, III, and IV, respectively, and were then compared to the corresponding histological pancreatic conditions. RESULTS: Pancreatic carcinomas demonstrated type-III (n=13) or IV (n=20) TIC. Tumor-forming pancreatitis showed type-II (n=5) or III (n=3) TIC. All islet cell tumors revealed type-I. The type-IV TIC was only recognized in pancreatic carcinoma, and the TIC of carcinoma always depicted the slowest rise to a peak among the 3 pancreatic TICs measured in each patient, even in patients with chronic pancreatitis. CONCLUSION: Pancreatic TIC from dynamic MRI provides reliable information for distinguishing pancreatic carcinoma from other pancreatic masses, and may enable us to avoid unnecessary pancreatic surgery and delays in making a correct diagnosis of pancreatic carcinoma, especially, in patients with longstanding chronic pancreatitis.


Assuntos
Imageamento por Ressonância Magnética/métodos , Neoplasias Pancreáticas/complicações , Neoplasias Pancreáticas/diagnóstico , Pancreatite Crônica/diagnóstico , Pancreatite Crônica/etiologia , Adenoma de Células das Ilhotas Pancreáticas/complicações , Adenoma de Células das Ilhotas Pancreáticas/diagnóstico , Adenoma de Células das Ilhotas Pancreáticas/patologia , Idoso , Idoso de 80 Anos ou mais , Diagnóstico Diferencial , Feminino , Humanos , Insulinoma/complicações , Insulinoma/diagnóstico , Insulinoma/patologia , Masculino , Pessoa de Meia-Idade , Pâncreas/patologia , Neoplasias Pancreáticas/patologia , Pancreatite Crônica/patologia , Estudos Retrospectivos
14.
Int J Oncol ; 26(5): 1307-12, 2005 May.
Artigo em Inglês | MEDLINE | ID: mdl-15809722

RESUMO

Mammographic density reflects comprehensive changes in the mammary gland. The condition of the tumour microenvironment is a possible factor affecting tumour progression, as well as a tumour risk factor. This study aimed to determine whether mammographic density correlates with tumour clinicopathological features and prognosis in breast cancer patients. The analysis involved 163 Japanese women who underwent surgery for breast cancer between 1999 and 2003 in the Nagasaki University Hospital, Japan. Mammographic density was classified according to the breast imaging reporting and data system (BI-RADS) categories 1-4. Age, tumour size, axillary lymph node involvement, steroid receptor (SR) status, histological grade and Nottingham prognostic index (NPI) were analysed by density category and tested for statistically significant differences across categories. A significant difference (P<0.05) by breast-density category was found only for age. SR-negative tumours had significantly worse NPI scores than SR-positive tumours in breast-density categories 2 (P=0.03) and 4 (P<0.001). A high distant-metastasis frequency was observed in category 4 SR negatives (44%) versus category 4 SR positives (4.3%). These findings reveal that although the BI-RADS breast-density category alone is not associated with prognosis in breast cancer, patients who are both category 4 and SR negative have an extremely poor prognosis.


Assuntos
Neoplasias da Mama/diagnóstico por imagem , Neoplasias da Mama/patologia , Mamografia/estatística & dados numéricos , Fatores Etários , Idoso , Neoplasias da Mama/cirurgia , Feminino , Seguimentos , Humanos , Pessoa de Meia-Idade , Prognóstico , Receptores de Esteroides/análise
15.
Nihon Igaku Hoshasen Gakkai Zasshi ; 64(3): 99-106, 2004 Mar.
Artigo em Japonês | MEDLINE | ID: mdl-15148784

RESUMO

The purpose of this study was to correlate strongly hyperintense areas(SHI) in breast lesions on FS-T2WI with histopathology and to evaluate the usefulness of the distribution patterns of SHI in the differentiation of benign and malignant breast lesions. MR imaging with pathological correlation was available in 157 breast lesions of 153 patients. The distribution patterns of SHI were classified into seven types. SHI on FS-T2WI was identified in 36 of 157 breast lesions. The irregular and inhomogenous types corresponded to various histological features and were only seen in malignant lesions. The central type corresponded to central necrosis and was only seen in 2 solid-tubular carcinomas. The crescent type corresponded to peripheral fluid collection in the intracystic tumor. The septal type corresponded to fibromyxoid stroma with fibrous septations in the lesions except for one cavernous hemangioma, and was only seen in benign lesions. The smooth type corresponded to mucinous pool, fibromyxoid stroma, and ductal dilatation and did not contribute to differentiation between benign and malignant lesions only on FS-T2WI. SHI in breast lesions on FS-T2WI pathologically corresponded to mucin, fibromyxoid change, necrosis, and ductal dilatation. Evaluation of patterns of SHI is useful in differentiating between benign and malignant lesions.


Assuntos
Doenças Mamárias/diagnóstico , Neoplasias da Mama/diagnóstico , Imageamento por Ressonância Magnética/métodos , Adolescente , Adulto , Idoso , Idoso de 80 Anos ou mais , Doenças Mamárias/patologia , Neoplasias da Mama/patologia , Diagnóstico Diferencial , Feminino , Humanos , Pessoa de Meia-Idade
16.
Eur Radiol ; 12 Suppl 3: S105-8, 2002 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-12522616

RESUMO

We report a case of sarcoidosis of the breast in a 31-year-old woman who presented with a palpable breast mass. The mammography showed a spiculated mass without any microcalcifications. Ultrasonogram showed a hypoechoic mass. Computed tomography showed a spiculated nodule. T2-weighted MR images with fat-suppression technique showed a mass with irregular border that appeared to be an accumulation of small nodules. Gadolinium-enhanced dynamic study showed gradually increasing signal intensity. She underwent excisional biopsy and the pathological findings were consistent with that of sarcoidosis. The MRI findings were well correlated with histopathological appearance.


Assuntos
Doenças Mamárias/diagnóstico , Sarcoidose/diagnóstico , Adulto , Doenças Mamárias/patologia , Diagnóstico Diferencial , Feminino , Humanos , Imageamento por Ressonância Magnética , Mamografia , Sarcoidose/patologia , Tomografia Computadorizada por Raios X , Ultrassonografia de Intervenção
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