[X-ray cardiometric indices of healthy persons and patients with diffuse toxic goiter in the alpine climate of the Tien Shan]. / Pokazateli rentgenokardiometrii u zdorovykh lits i bol'nykh diffuznym toksicheskim zobom v usloviiakh gornogo klimata Tian'-Shania.

Roentgenometric analysis of morphological changes of the heart was made in 114 healthy individuals and 192 patients with diffuse toxic goiter living in the Tien Shan mountains. It is shown that the main dimensions of the heart and Moore's index pointing to pulmonary hypertension increase as the disease advances and is more marked in the people living in high altitudes. Diastolic and systolic volumes of the heart in patients with diffuse toxic goiter show a statistically significant increase (p less than 0.001). Increase of the stroke and minute volumes of the blood, caused by cardiac hyperfunction, is manifest already at the early stage of the disease and is directed at satisfying the enhanced demands for oxygen by tissues. Combination of high indices of stroke and minute volumes of the heart with normal heart rate or comparatively slight increase in the patients living in high altitudes of the Tien Shan is an advantageous adaptive-compensatory reaction of the body in response to the impact of internal and external factors of the mountain climate.