RESUMO
The frequency of blood groups ABO, Rh, MNS, P, haptoglobin as well as distribution of phenotypic combinations of two different loci are compared in groups of children and adults. The frequency of phenotype O, Rh-negative and P-positive people is revealed to increase in adults, that testifies to the influence of the age factor on the distribution of the human polymorphic blood systems.
Assuntos
Envelhecimento/genética , Antígenos de Grupos Sanguíneos/genética , Frequência do Gene , Fenótipo , Polimorfismo Genético , Sistema ABO de Grupos Sanguíneos/genética , Adolescente , Adulto , Envelhecimento/sangue , Criança , Haptoglobinas/genética , Humanos , Sistema do Grupo Sanguíneo MNSs/genética , Sistema do Grupo Sanguíneo P/genética , Sistema do Grupo Sanguíneo Rh-Hr/genéticaAssuntos
Tonsilite/genética , Sistema ABO de Grupos Sanguíneos , Adolescente , Antígenos/análise , Criança , Pré-Escolar , Doença Crônica , Cárie Dentária/genética , Doenças da Vesícula Biliar/genética , Haptoglobinas/análise , Humanos , Fenótipo , Doenças Reumáticas/genética , Cromatina Sexual/análiseRESUMO
Studies of theincidence of ABO, MN and Rh blood groups were carried out in 896 patients aged 40-89 with cardiovascular diseases and in 523 healthy people of the same age. High occurence of cardiovascular diseases was observed in patients having A and MM blood groups. The coefficient of relative morbidity A : 0 and MM:(NN +MN) depends on the age, the degree and the prevailing localization of the pathological process.