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Ann Plast Surg ; 82(6): 642-645, 2019 06.
Artigo em Inglês | MEDLINE | ID: mdl-30730320

RESUMO

Gout is a disease characterized by abnormal metabolism of the uric acid, leading to undesired buildup of monosodium urate crystals affecting mainly the first metatarsal-phalangeal joint of the foot and less commonly other joints or the soft tissues of the body. The prevalence of the disease increases with age, and it is statistically more observed in men than in women.We present the case of a 62-year-old male patient diagnosed as having gout 20 years ago. He came to the clinic with a nasal hump and a mass growing in his nose for the last 3 years, presenting as a nasal obstruction and facial deformity. Although the patient was treated with allopurinol and nonsteroidal anti-inflammatory drugs, surgical treatment was deemed necessary, and the patient was taken to receive a surgical resection of the nasal mass. The follow-up histopathology observation revealed deposits of urate crystals surrounded by a granulomatous inflammation. This confirmed the diagnosis-gouty tophi in the nose. In the follow-up period after the surgery, the patient reported overall improved breathing and aesthetic results.Tophi can be found in atypical locations, which increases morbidities and deformities caused by the disease. We report on this peculiar case of tophaceus gout as it is-a rare manifestation of the disease with tophi located in the nasal region.


Assuntos
Alopurinol/uso terapêutico , Gota/complicações , Cavidade Nasal/diagnóstico por imagem , Obstrução Nasal/etiologia , Obstrução Nasal/cirurgia , Biópsia por Agulha , Gota/sangue , Gota/tratamento farmacológico , Humanos , Imuno-Histoquímica , Masculino , Pessoa de Meia-Idade , Cavidade Nasal/cirurgia , Obstrução Nasal/diagnóstico por imagem , Nariz/fisiopatologia , Nariz/cirurgia , Prognóstico , Medição de Risco , Tomografia Computadorizada por Raios X/métodos , Resultado do Tratamento , Ácido Úrico/sangue
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