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J Diabetes Investig ; 10(2): 331-338, 2019 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-30175458

RESUMO

AIMS/INTRODUCTION: The present study aimed to investigate the effects of low-intensity resistance training with slow movement and tonic force generation (LST) on muscular function and glucose metabolism in older patients with type 2 diabetes. MATERIALS AND METHODS: A total of 10 patients with type 2 diabetes (age 68.2 ± 9.7 years) engaged in LST training twice a week for 16 weeks. Before the long-term intervention, they were subjected to the measurement of acute changes in blood factors relating to glycemic control as a result of a bout of LST. Body composition, muscular size and strength, and glycated hemoglobin were measured before and after the intervention. RESULTS: The magnitudes of the acute changes in the blood factors were all small and were not considered harmful for glucose metabolism. The 16-week LST training caused significant increases in thigh muscle thickness and strength, and decreases in body fat mass and glycated hemoglobin. The change in glycated hemoglobin showed a significant negative correlation with the change in the isokinetic knee extension peak torque measured at a high angular velocity (180°/s). CONCLUSIONS: The LST training was shown to be effective for gaining muscular size and strength, and improving glycemic control in older patients with type 2 diabetes. The mechanisms underlying this effect might involve the improvement of contractile function in fast glycolytic fibers.


Assuntos
Biomarcadores/análise , Diabetes Mellitus Tipo 2/terapia , Índice Glicêmico , Força Muscular/fisiologia , Músculo Esquelético/fisiologia , Treinamento Resistido , Adulto , Idoso , Idoso de 80 Anos ou mais , Glicemia/análise , Composição Corporal , Estudos de Casos e Controles , Diabetes Mellitus Tipo 2/sangue , Diabetes Mellitus Tipo 2/patologia , Feminino , Seguimentos , Hemoglobinas Glicadas/análise , Humanos , Masculino , Pessoa de Meia-Idade , Prognóstico
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