Acquired agminated melanocytic nevus in the acral area is a potential mimicker of acral lentiginous melanoma: A three-case series report and published work review.

Agminated nevus refers to a clustered group of melanocytic nevi confined to a localized area of the body. It rarely involves acral skin, but recognition of acquired agminated nevus (AAN) in the acral area is clinically important because it may mimic acral lentiginous melanoma (ALM). However, acral AAN has only been described in a few case reports and its clinical characteristics remain unclear. We report three additional cases of acral AAN to further analyze the differential points between ALM. Clinical images, including those of dermoscopy, of three cases of acral AAN were reviewed. The lesions were located on the sole or lateral border of the foot. All acral AAN were flat and large in size (>20 mm in greatest dimension), and associated with asymmetry and irregular border. However, no parallel ridge pattern suggesting ALM was observed on dermoscopy. In two patients, the lesions on the sole were totally resected; microscopic evaluation of these two lesions confirmed junctional nests of banal melanocytes. AAN lesions on the sole with chronic mechanical pressure are slightly larger and more diffuse; thus, they may be more likely to be overdiagnosed as malignancy upon inspection than those in the non-acral area. Understanding the concept of the disease and careful dermoscopic evaluation leads to an accurate diagnosis.

Revival of favus in Japan caused by Trichophyton schoenleinii.

Favus is a type of dermatophytosis known to produce yellow scutula around hair follicles. Most cases of this disease worldwide are infections of Trichophyton schoenleinii. Favus has rarely been reported in Japan throughout the last four decades, and T. schoenleinii has not been clinically isolated in any case during the period. Here, we report a case of favus of vellus hair observed in a 63-year-old Japanese woman. Fungal culture showed negative; however, we detected fungal elements in the crust and hair bulbs by Grocott staining. Pathogenic fungi were identified as T. schoenleinii by polymerase chain reaction-based DNA sequencing, targeting the internal transcribed spacer regions of the rRNA gene using the formalin-fixed, paraffin-embedded tissue sample. She was successfully treated with p.o. administration of terbinafine and topical application of luliconazole cream.

A molybdenum complex bearing a tetraphosphine ligand as a precursor for heterobimetallic complexes.

The reactions of [CpMoH(κ(3)-P4)] (2; P4 = meso-o-C6H4(PPhCH2CH2PPh2)2) with protic acids gave [CpMo(κ(4)-P4)](+) (4(+)) via the intermediary formation of [CpMoH2(κ(3)-P4)](+). Treatment of 2 with iodine provided the cationic complex [CpMoHI(κ(3)-P4)][I] (5[I]). Early-late heterobimetallic complexes of the type [CpMoH(µ-P4-1κ(3):2κ)MLnCl] (MLn = Ru(Hmb)Cl (6), Ir(η(5)-C5Me5)Cl (7), Rh(cod), Ir(cod), Pd(η(3)-C3H5) (10); Hmb = η(6)-C6Me6, cod = η(4)-1,5-cyclooctadiene) were synthesised by reacting 2 with [MLn(µ-Cl)]2, and their structures were characterised by NMR spectroscopy. The hydride ligand in 6 was replaced by chloride in chlorinated organic solvents to give [CpMoCl(µ-P4-1κ(3):2κ)Ru(Hmb)Cl2] (11). Self-reaction of 10 produced allylbenzene and [CpMo(µ-H){µ-PhP(CH2)2P(Ph)-o-C6H4-P(Ph)(CH2)2PPh2-1κ(3):2κ(2)}PdCl] (12), in which the Mo-Pd edge was bridged by a hydride ligand and the phosphide moiety emerged from the loss of one phenyl group. The molecular structures of 4[Cl], 4[OTf], 5[I], 6, 7, 11, and 12 were established by single-crystal X-ray analysis.

Preparation of a bis(hydrosulfido) complex of Mo having a tetraphosphine co-ligand and its transformation into MoRh2 and MoIr2 mixed-metal sulfido clusters.

The treatment of a Mo(0) complex with a tetraphosphine co-ligand [Mo(kappa(4)-P4)(Ph(2)PCH(2)CH(2)PPh(2))] (P4 = meso-o-C(6)H(4)(PPhCH(2)CH(2)PPh(2))(2)) with H(2)S gas in toluene at room temperature afforded [Mo(SH)(2)(kappa(4)-P4)] (1), which demonstrates the first Mo(II) bis(hydrosulfido) complex. Its trigonal-prismatic structure rarely observed for Mo(II) complexes has been determined by X-ray analysis. The reactions of 1 with [RhCl(CO)(2)](2) and [IrCl(CO)(2)(p-toluidine)] in the presence of NEt(3) resulted in the formation of the sulfido-bridged trinuclear clusters [Mo(kappa(4)-P4)(mu(3)-S)(2){Rh(CO)(2)}(2)] (4) and [Mo(kappa(4)-P4)(mu(3)-S)(2){Ir(CO)(2)}(2)] (5), respectively. The X-ray diffraction study has disclosed that the MoRh(2) cluster 4 in the solid state exists in two isomeric forms arising from the different orientation of P4 to the trigonal-prismatic Mo center, whereas the crystals of the Ir analogue 5 contains the molecules corresponding to only one of the two isomers observed for 4. The fluxional features of 1, 4, and 5 in solution have been confirmed by VT NMR studies.