[A trial of using a dry bifidobacterin preparation with newborn risk groups to prevent acute intestinal infections]. / Opyt primenenia preparata sukhogo bifidumbakterina novorozhdennym grupp riska s tsel'iu profilaktiki ostrykh kishechnykh infektsii.

The dried preparation of bifidumbacterin was administered to newborn infant during 4-6 days of their stay in a maternity clinic. The test group consisted of 110 infants and the control group, of 115 infants. Bacteriological studies indicated that the administration of bifidumbacterin produced a positive effect on the formation of the intestinal microflora in infants. During the first 3 months of life the registered cases of acute enteric infections among the children of the test group were 3 times less frequent than among the children of the control group. A perceptible prophylactic effect produced by this preparation with respect to purulent septic infections of the skin and the buccal mucosa was also noted.

[The immunological effectiveness of small doses of diphtheria and tetanus anatoxins in the revaccination of children with allergy-altered reactivity and adults]. / Immunologicheskaia éffektivnost' malykh doz difteriinogo i stolbniachnogo anatoksinov pri revaktsinatsii detei s allergicheski-izmenennoi reaktivnost'iu i vzroslykh.

The possibility of decreasing the content of antigens in adsorbed diphtheria-tetanus toxoid, used for the booster immunization of children with allergically altered responsiveness and adults, is shown. Diphtheria toxoid in doses of 1-2.5 Lf and tetanus toxoid in doses of 1-2.5 binding units possessed sufficiently high immunological effectiveness in combination with low reactogenicity and good tolerance. In 6-12 months after booster immunization with decreased doses of toxoids 100% of children with allergy of different character and, respectively, 86-94% and 95% of adults have developed protective levels of antibodies to diphtheria and tetanus.