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1.
Cureus ; 16(4): e57455, 2024 Apr.
Artigo em Inglês | MEDLINE | ID: mdl-38699114

RESUMO

Platelets are blood components produced in the bone marrow and are essential in forming blood clots. Thrombocytosis refers to a condition that causes the excess production of platelets in the body. When it develops as a reaction to an infection, trauma, or surgery, it is known as secondary or reactive thrombocytosis. Although thrombocytosis is typically a self-limiting disorder, it can frequently result in hemorrhagic or thrombotic events. Extreme thrombocytosis may trigger thrombotic events. Therefore, clinicians must be aware of the complications of thrombocytosis. In this case report, a 35-year-old female, known to have portal hypertension and Budd-Chiari syndrome, presented with complaints of weakness and tingling in her hands persisting for eight days. She disclosed that she had undergone an elective splenectomy as part of her management for portal hypertension and Budd-Chiari syndrome eight days prior.

2.
Cureus ; 16(3): e56377, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38633966

RESUMO

The Dyke-Davidoff-Masson syndrome (DDMS) is an uncommon neurological disorder whose prevalence is not yet known. There have only been 21 adult manifestations of this rare brain disorder, out of around 100 cases previously documented. Diagnosis is challenging because of the complexity of radiological findings and clinical symptoms, which include ventricle dilation, hypertrophy of the cranial bones, increased pneumatization of the sinuses, and cerebral hemisphere atrophy. It can be inherited or acquired from infections, brain hemorrhage, and hypoxia during pregnancy. Usually, neuroimaging is used to diagnose it. This case study reports the case of a 17-year-old girl who had complex partial seizures at the age of 17 and right-side paralysis since she was three years old.

3.
Cureus ; 15(10): e47653, 2023 Oct.
Artigo em Inglês | MEDLINE | ID: mdl-38021622

RESUMO

Inherited arrhythmias, encompassing conditions such as cardiomyopathies, cardiac ion channel disorders, and coronary heart disease, represent the common causes that elevate the threat of sudden cardiac death among adults. Researchers have pinpointed the genes responsible for these hereditary arrhythmias in the last 30 years. Concurrently, it has become clear that the genetic makeup underlying these conditions is more intricate than previously understood. Evolution in DNA sequencing techniques, particularly next-generation sequencing, has empowered us to learn these intricate hereditary characteristics. Genetic testing is crucial in diagnosing, assessing risk, and determining treatment for individuals with these conditions and their family members. The need for collaborative endeavors to comprehend and address these uncommon yet potentially life-threatening disorders is becoming more evident. This review aims to inform readers of the latest advances in understanding hereditary arrhythmias and provide the groundwork for collaborative genetic testing initiatives to characterize these disorders in the general population.

4.
Cureus ; 14(8): e28032, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-36120284

RESUMO

Nowadays, neurological problems are more regular, representing a worry to pregnant ladies, guardians, healthy babies, and kids. Neurological problems emerge in a wide assortment of structures, each with its arrangement of beginnings, inconveniences, and results. The conclusion of neurological illnesses is an evolving concern and predominantly troublesome difficulty for current medication. Current diagnosis advancements (e.g., MRI and EEG) produce immense information (in proportion and aspect) as location, checking, and therapy of nervous system illnesses. As a common rule, investigation of that enormous clinical information is performed physically by specialists to distinguish and figure out the irregularities. It is a genuinely troublesome errand for an individual to collect, make due, investigate, and absorb enormous amounts of information through visible review. As an outcome, the specialist has been requesting electronic conclusion frameworks known as "computer-aided diagnosis" that can consequently identify the nervous system irregularities utilizing the essential clinical information. This framework further develops uniformity of findings, builds treatment outcomes, protects lives, and lessens price and time. As of late, few examinations have improved the computer-aided design frameworks for the executives of enormous clinical information for determination appraisal. This paper investigates the difficulties of tremendous clinical information giving. This article fundamentally evaluated and looked at the exhibition of existing AI and comprehensive learning approaches for identifying nervous system illnesses. A far-reaching piece of this concentration also shows different modalities and illness-determined datasets that identify and record pictures, signs, addresses, and so forth. Restricted related works are additionally summed up on nervous system illnesses, as this space has essentially less work zeroed in on illness and recognition rules. A portion of the standard assessment measurements is likewise introduced in this review for improved outcome examination.

5.
Cureus ; 14(8): e28463, 2022 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-36176831

RESUMO

Three-dimensional (3D) bioprinting is a cutting-edge technology that has come to light recently and shows a promising potential whose progress will change the face of medicine. This article reviews the most commonly used techniques and biomaterials for 3D bioprinting. We will also look at the advantages and limitations of various techniques and biomaterials and get a comparative idea about them. In addition, we will also look at the recent applications of these techniques in different industries. This article aims to get a basic idea of the techniques and biomaterials used in 3D bioprinting, their advantages and limitations, and their recent applications in various fields.

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