Observation and Assessment of the Parameters of Facial Esthetics in 6-year-old Children with Healthy Dentition.

Aim: This study was conducted to observe and assess the dental and facial parameters of esthetics in children with healthy dentition and evaluate whether they are comparable to those of adults. Materials and methods: An observational study included 70 children with ages ranging from 5 to 6 years who had come to the Department of Pediatric & Preventive Dentistry, Institute of Dental Studies & Technologies, Ghaziabad, Uttar Pradesh, India, with intact primary dentition. Standardized photographs of the children were taken and evaluated. Their facial and dental parameters were recorded and compared to that of those of adults. Result: The relation of tooth and facial components was established, and it was found that they were not in the same proportion as those of adults. Conclusion: The proportions of facial and dental parameters of esthetics of children at 6 years of age are different from those of adults. Clinical significance: Since esthetic rehabilitation of primary teeth is becoming an important requisite of successful dental treatment, it is important to establish a standard guideline of dental and facial parameters for children for prosthetic rehabilitation. How to cite this article: Potsangbam D, Agarwal N, Jabin Z, et al. Observation and Assessment of the Parameters of Facial Esthetics in 6-year-old Children with Healthy Dentition. Int J Clin Pediatr Dent 2023;16(4):608-611.

Pathway to mercury-free dentistry: an insight into past, present, and future.

Purpose: The popularity of dental amalgam arises from its excellent long-term performance, ease of use, and low cost. However, there is a concern about the potential adverse health effects arising from exposure to mercury in amalgam. This review article critically discusses the safety of dental amalgam as a restorative material and our preparedness for a mercury-free road ahead. Materials and methods: A database search was performed on PubMed and Google scholar using the keywords: "mercury-free dentistry", "mercury toxicity", "amalgam substitutes", "amalgam mercury toxicity". Inclusion and exclusion criteria were specified clearly. Relevant literature was also searched in the dental textbooks. Results: Around 40 articles, highlighting mercury exposure among dental professionals and patients were included. Despite the overwhelming body of scientific evidence demonstrating amalgam to be a safe restorative material, concerns about the toxic effects of mercury persist. Conclusion: The real challenge is to find a suitable amalgam substitute and to follow the mercury hygiene measures closely.

Comparative evaluation of antimicrobial efficacy of nanosilver solution, Azadirachta indica, sodium hypochlorite, and normal saline as root canal irrigants in primary teeth.

Background: Microorganisms are the main cause of pulpal and periapical diseases. Hence, the elimination of such potential microbes is achieved by endodontic treatment. Mechanical preparation is the main mechanism to reduce the bacterial load in canals which is enhanced by intracanal irrigants. Despite these procedures, some bacteria might persist within the canals. It is important to disinfect the pulp space and dentinal tubules thoroughly with an effective endodontic irrigant to prevent reinfection of a treated root canal. Aim: This study aimed to evaluate and compare the antimicrobial efficacy of nanosilver (NS) Solution, Azadirachta indica, sodium hypochlorite, and normal saline when used as irrigants in infected root canals of primary teeth. Settings and Design: The study was a prospective randomized control trial which was conducted as per the consort statement. Materials and Methods: Eighty pulpally involved primary teeth requiring endodontic treatment of children aged 5-12 years were selected for this study. The subjects were randomly allocated to 4 groups (3 irrigant and control groups) consisting of 20 children each where Group I = NS solution, Group II = A. indica, Group III = Sodium hypochlorite (2.5%), and Group IV = Control group. Microbiological samples were collected at the baseline (before irrigation) and postirrigation after biomechanical preparation using the selected irrigant. The samples were subjected to an anaerobic bacterial culture test. Microbial colonies were identified and expressed as colony forming units per milliliter. Statistical Analysis: Data were analyzed using one-way analysis of variance, Paired t-test, and Post hoc Bonferroni test. Results: NS solution showed the highest mean of 4.384 × 103 ± 1.019 followed by Sodium hypochlorite with a mean of 3.500 × 103 ± 1.193 and A. indica of 2.590 × 103 ± 0.778. Conclusion: Based on the results of this study, NS solution can be used as an alternative to other root canal irrigating solutions in primary teeth.

Effect of nanoparticle based intra-canal medicaments on root dentin micro-hardness.

Complete eradication of bacterial infection from the root canal with minimum or no effect on the microhardness of the dentin is desirable for the success of endodontic treatment. The effect of nanoparticle based intracanal medicaments on the root dentine microhardness was assessed. The medicaments used were combination of calcium hydroxide - silver nanoparticles, Combination of graphene oxide - silver nanoparticles, Calcium hydroxide and a control group. Vickers hardness value were evaluated and compared at coronal, middle and apical third level. Graphene oxide - silver nanoparticles based intracanal medicament showed least effect on the microhardness of the root dentin compared to calcium hydroxide and calcium hydroxide combined with silver nanoparticle based intracanal medicaments.

Green synthesis of calcium hydroxide-coated silver nanoparticles using Andrographis paniculata and Ocimum sanctum Linn. leaf extracts: An antimicrobial and cytotoxic activity.

Context: Silver is known for its antibacterial properties since ages. As nanoparticles have smaller size and greater surface area, silver has been utilized in the form of nanoparticles to enhance its antibacterial properties. Calcium hydroxide is a well-known intracanal medicament and serves as a gold standard for root canal disinfection. Using herbal extracts as reducing agents for nanoparticle synthesis appears to be an ecofriendly approach. Aim: The aim of this study was to synthesize calcium hydroxide-based silver nanoparticles using herbs as reducing agents and to test the cytotoxic levels and antimicrobial activity against oral microbes. Materials and Methods: The calcium hydroxide-based silver nanoparticles were synthesized using the leaves of Andrographis paniculata and Ocimum sanctum Linn. Various properties of the synthesized nanoparticles were also characterized by ultraviolet (UV) spectrophotometer analysis, transmission electron microscopy (TEM), X-ray diffraction (XRD), and Fourier-transform infrared spectroscopy (FTIR) analysis. The cytotoxic effects of these nanoparticles were analyzed using brine shrimp and MTT assay. Antimicrobial activity was assessed by measuring the zone of inhibition. The statistical analysis was done using parametric independent t-test. P value was set at < 0.05. Results: The calcium hydroxide-based silver nanoparticles were successfully synthesized and were confirmed by UV spectrophotometer analysis, TEM, X-ray diffraction (XRD), and FTIR analysis and showed a minimal cytotoxic effect. They also showed a good antimicrobial activity and a remarkable antifungal activity. Conclusions: The green synthesis of CaOHAgNPs yielded an effective nanoparticle preparation that could be used against common oral pathogens as a potential therapeutic agent in the form of root canal irrigant or intracanal medicament in the field of dentistry.

Comparative Evaluation of Salivary Fluoride Concentration after Topical Application of Silver Diamine Fluoride and Sodium Fluoride: A Randomized Controlled Trial.

Background: The topical fluoride acts on the tooth in many ways and their most important action is inhibition of demineralization and enhancement of enamel remineralization. Aim: The purpose of this clinical trial was to assess the fluoride concentration in saliva before and after 38% silver diamine fluoride (SDF) and 5% sodium fluoride (NaF) application on enamel and duration of its availability at different time intervals. Methodology: A randomized clinical trial was conducted among 40 healthy children aged between 6 and 12 years. The participants were then randomly allocated into two different groups in which the first group (group I) was given 30% SDF and the second group (group II) were topically applied with 5% NaF solution. The fluoride concentration was measured in the salivary samples, which were collected at three time intervals, that is, at baseline (S1), 2 hours (S2), and 24 hours (S3) after application. Analysis of variance (ANOVA) test was used for evaluation and independent paired t-test was conducted for comparison between groups. Results: When using an ANOVA with repeated measures with a Greenhouse-Geisser correction, the mean scores of fluoride concentration were statistically significantly different at different time intervals for both NaF (F = 20.854, p < 0.0005) and SDF (F = 22.746, p < 0.0005). Conclusion: The present trial concluded that topical fluoride application increases fluoride bioavailability in saliva thereby increasing tooth remineralization. A steep rise in fluoride concentration was observed shortly post-SDF application at 2 hours and 24 hours time interval emerging a need for further research into the field of fluoridation with SDF. How to cite this article: Jabin Z, Nasim I, Priya V V, et al. Comparative Evaluation of Salivary Fluoride Concentration after Topical Application of Silver Diamine Fluoride and Sodium Fluoride: A Randomized Controlled Trial. Int J Clin Pediatr Dent 2022;15(3):371-375.

Effectiveness of Oral Probiotics in Reducing S. Mutans Count in Caries-active Children: A Comparison with Chlorhexidine and Herbal Mouthrinse (Hiora®).

Aim: The purpose of this study was to compare the reduction in salivary mutans streptococci counts and to evaluate any change in the salivary pH values after the use of oral probiotics, chlorhexidine, and herbal mouthrinse. Method: Oral probiotics, chlorhexidine, and herbal mouthrinse [Hiora®] were evaluated for their efficacy against S. mutans in 75 caries-active children, aged 6-14 years. Results: The values obtained were subjected to statistical analysis. Oral probiotics showed lesser reduction in the S. mutans count as compared to chlorhexidine but the values were statistically insignificant. Herbal mouthrinse was not as effective as the oral probiotics or chlorhexidine in reducing the S. mutans count. Conclusion: Oral probiotics show a similar efficacy as the gold standard, chlorhexidine, in reduction of oral S. mutans. How to cite this article: Kamble A, Jabin Z, Agarwal N, et al. Effectiveness of Oral Probiotics in Reducing S. Mutans Count in Caries-active Children: A Comparison with Chlorhexidine and Herbal Mouth-rinse (Hiora®). Int J Clin Pediatr Dent 2022;15(S-2):S207-S211.

Top 100 cited articles on Silver diamine fluoride-A bibliometric analysis.

Background: Identification of top cited articles aids in providing comprehensive and cumulative standardized quality work to research community. The present bibliometric study was aimed at identifying 100 top cited articles on Silver diamine fluoride, highlighting its landmark publications available in the current literature and aids in providing comprehensive and cumulative standardised quality work to research community. Methodology: Four major databases (Web of science, Pubmed, Scopus and Embase) were searched using search terms like 'silver fluoride' OR 'silver diamine fluoride' OR 'silverdiammine fluoride' OR 'diamine silver fluoride' OR 'diammine silver fluoride' OR silver ammonia fluoride AND dentistry. Selected publications were studied to tabulate information like journal, authors, year etc and contents of the publications were summarised. Variables such as journal name, first author, journal rank, citation count and average citations per year, authorship patterns, author's country of origin, most productive authors, journals and countries were identified. Additional outcome variables were SDF concentrations used, study designs adopted and SDF use like caries arrest/prevention/anti-hypersensitive agent and as an irrigant. Results: Among them maximum articles were clinical trials(n = 24) however systematic(n = 12), literature(n = 14) and narrative reviews(n = 12) had an equal share. The countries with the highest number of most-cited papers were China and USA. The most studied aspect was caries arrest. Journal of Dentistry and Journal of Dental Research had major publications among top cited papers. Conclusion: This particular review will prove to be a great source of information for research community worldwide and will aid in directing them towards relevant articles.

Antimicrobial effectiveness of Nano Silver Fluoride Varnish in reducing Streptococcus mutans in saliva and plaque biofilm when compared with Chlorhexidine and Sodium Fluoride Varnishes.

Background: This in vivo study was done to investigate the antimicrobial effectiveness of Nano Silver fluoride, Sodium fluoride and Chlorhexidine when used as a varnish on Streptococcus mutans (S.mutans) in saliva and plaque biofilm. Material and Methods: 120 caries free subjects, aged 8-10 years were randomly assigned to four different groups (n=30) - group I: Control, group II: Chlorhexidine varnish (CHX), group III: Sodium fluoride varnish (NaF), group IV: Nano Silver fluoride varnish (NSF). Varnish application was done once at baseline. Saliva and plaque samples were collected at baseline (T0), at the end of 1 month (T1) and 3 months (T3) to evaluate S.mutans levels by culture method, optical density and PCR. OHI-S Index was also recorded for clinical evaluation. Results: NSF, CHX and NaF were effective against S.mutans activity. The intragroup comparision of CFU/ml and OD/ml count showed a highly significant reduction from baseline to 3 months for all the 3 varnish groups (p=0.001). PCR result revealed that maximum reduction was seen in NSF and CHX followed by NaF group. Conclusions: NSF reduces S.mutans level in both saliva and plaque biofilm and it is more advantageous than CHX and NaF as it has dual properties of acting as an antibacterial as well as a remineralizing agent. Key words:Chlorhexidine, Nano Silver fluoride, Sodium fluoride, S. mutans, varnish.

Parental knowledge, awareness and acceptance of silver diamine treatment among patients from Modinagar, Uttar Pradesh, India.

Silver diamine fluoride has emerged as a non invasive effective therapy for arresting active carious lesions. Therefore, it is of interest to assess parental knowledge, awareness and acceptance of SDF. A cross sectional questionnaire based survey was conducted among 62 parents visiting the Department of Pedodontics along with their children in Modinagar. A 15 item pre-validated questionnaire was used to record baseline characteristics of child's parents and their knowledge, awareness and acceptance of SDF for their child for prevention of dental caries. 80.6% participants were aware that SDF is painless procedure whereas majority of the participants were not sure about whether placement of filling required post SDF treatment (48.4%), SDF treatment be done outside dental clinic (61.3%), and about any agents that reduce SDF staining (64.5%). Majority 71% participants were aware about SDF treatment's side effects, 90.3% aware whether their child experienced teeth blackening after SDF treatment and 83.9% aware about whether SDF treatment immediately relieves the child's pain. 90.3% preferred SDF treatment, 83.9% opted for SDF treatment despite of its tooth blackening effects. A statistically significant association was found between SDF acceptance and age of their child. There is a lack of knowledge about SDF among the study participants emerging a need for proper education to them when they visit a dental setting with their child. Although it causes discolouration of teeth post SDF treatment, still parents are willing to accept SDF as a treatment modality for their child's oral health.

Professional protocol and rational outlook of dentists towards SDF.

SDF has gained immense popularity worldwide in the recent years due to its dual performance brought about by inhibiting bacterial growth as well as promoting the remineralisation of dental hard tissues. This study aims to evaluate the knowledge and attitude among dentists towards Silver Diamine Fluoride (SDF). The present study is an online survey which was designed using Google forms, to gather information about the knowledge and professional protocol followed by dentists for SDF use in their respective operatories. Written informed consent was obtained from the participants after explaining to them the purpose of the study. The detailed questionnaire comprised of two sections. First section comprised of 15 questions which inquired about SDF knowledge and protocols followed for its use by dentists. Second section analyzed rational outlook of dentists towards SDF. Sample selection was done by simple random sampling and questionnaire Google link was circulated among 224 dentists. The mean age group of the participants is 33.82 ± 12 years. A statistically significant difference was found between the participant and the use of SDF in operatory, its application for performance in cavitated or non cavitated lesions, application intervals and the potential problems associated with SDF use. A majority of dentist (62.5%) knew that 38% concentration of SDF to be used among the children which is statistically significant. (p value ≤0.05).A lack of self-reported knowledge was most frequently reported concerning the use and application of SDF among patients to arrest carious lesions in primary and permanent teeth in a dental setting. Thus further studies can be of excellent utility especially for whole community with limited resources instead of using costly preventive strategies.

Antioxidant and anti-inflammatory activity of a nanoparticle based intracanal drugs.

The most common intracanal medication is calcium hydroxide. Its efficacy can be affected by a number of factors, including pH, serum proteins, collagen, and dentin. It's also ineffective against E. faecalis and fungus, lacks an anti-inflammatory component, and has mixed reviews when it comes to pain relief. Natural alternatives to synthetic intracanal medication are being researched at the moment. We evaluated the antioxidant and anti-inflammatory activity of green synthesized silver nanoparticle based intracanal medicaments. Silver nanoparticles integrated into calcium hydroxide and graphene oxide nanoparticles were the experimental groups and Calcium hydroxide served as the control. Antioxidant activity was determined using the DPPH and Nitric oxide assays, while anti-inflammatory activity was determined using the protein denaturation and Xanthine Oxidase Inhibition assays. Both experimental groups had higher antioxidant activity than the control group based on DPPH and Nitric oxide assays. Calcium hydroxide combined with silver nanoparticles demonstrated improved anti-inflammatory efficacy in a protein denaturation and Xanthine oxidase inhibition assay. Within the constraints of an in vitro study, it can be concluded that intracanal medicaments containing silver nanoparticles can be employed efficiently during root canal preparation. In comparison to standard calcium hydroxide-based intracanal medicaments, it has effective antioxidant and anti-inflammatory effects.

Assessing Videoconferencing as a Method of Remote Consultation in Pediatric Dentistry.

Background: The oral health condition in rural areas remains compromised due to insufficient healthcare providers. Implementation of teledentistry through videoconferencing in these areas can improve this situation when trained personnel are able to carry out real-time consultations of the patients with a pediatric dentist. Aim: To observe the feasibility of using teledentistry for an oral examination, consultation, and education, and also to assess the participant's satisfaction regarding the use of teledentistry for a routine dental checkup. Materials and methods: An observational study was carried out with 150 children aged 6-10 years. About 30 primary health centers (PHC)/Anganwadi (AW) workers were trained to perform the oral examination with the intraoral camera (IOC). Four self-constructed and nonstructured questionnaires were prepared to understand the knowledge, awareness, and attitude of the participants toward pediatric dentistry and their acceptance of teledentistry. Results: A total of 83.3% of children were not scared and felt that the use of IOC was better. About 84% of the PHC/AW workers found teledentistry very convenient, easy to learn, and adapt. And around 92% thought that teledentistry is time-consuming. Conclusion: Teledentistry is a possible way to provide pediatric oral health consultation in rural areas. It can save time, stress, and money for people in need of dental treatment. How to cite this article: Agarwal N, Jabin Z, Waikhom N. Assessing Videoconferencing as a Method of Remote Consultation in Pediatric Dentistry. Int J Clin Pediatr Dent 2022;15(5):564-568.

Salivary retention of silver diamine fluoride.

The topically applied fluorides are efficacious in both prevention against caries attack and inhibition of virulent bacteria. The purpose of this clinical trial was to assess the fluoride concentration in saliva before and after 38% SDF, 5% NaF and 1.23% ApF gel application on enamel and duration of its availability at different time intervals. The present randomized clinical trial was conducted among 60 healthy children aged between 6-12 years where at baseline the participants were instructed to spit for 2 min in sterile containers and the first saliva sample (S1) was taken. The participants were then randomly allocated into 3 different groups in which 38% Silver diamine fluoride, 5% Sodium fluoride and 1.23% ApF gel were applied respectively. The second saliva sample (S2) was collected after 5 min and patients were called after 1 hour for third saliva sample collection. The fluoride concentration was measured in the salivary samples. ANOVA test was used for evaluation and chi square t test was conducted for comparison of 3 groups. The fluoride concentration is comparatively slightly higher for the group receiving SDF than NaF and ApF at baseline, 5 min and 1 hour time interval but is not statistically significant. The mean scores of Fluoride concentration of the three groups were statistically significant at 5 min (F=63.556, p<0.0005) and 1 hour time interval (F=17.577, p<0.0005). Slightly increased salivary fluoride retention was observed post SDF application at 5min and 1 hour time interval when compared to Na F and ApF gel application. The present trial also concluded that topical fluoride application increases fluoride bioavailability in saliva thereby increasing tooth remineralization.

Comparative Evaluation of Cleaning Capacity and Efficiency of Kedo-S Pediatric Rotary Files, Rotary ProTaper, and Hand K Files in Primary Molar Pulpectomy.

AIM AND OBJECTIVE: To assess and compare the cleaning efficacy and instrumentation time of K files, ProTaper, and Kedo-S rotary files in primary molars. MATERIALS AND METHODS: India ink was injected into 120 root canals of selected primary molars. The root canals were randomly and equally divided into three groups based on instrumentation technique: group I-K files, group II-ProTaper, and group III-Kedo-S. After instrumentation with respective method, the canals were cleared and observed under a stereomicroscope, the instrumentation time for each root canal was also measured with a stopwatch. Statistical analysis was done with one-way analysis of variance (ANOVA) and post hoc Bonferroni. RESULT: Kedo-S rotary files performed significantly better cleaning of the canals in the coronal and middle third than ProTaper and K files (p = 0.0001). In the apical third, the difference between the two rotary systems was not significant. The time taken for instrumentation was lowest with Kedo-S followed by ProTaper and K files. CONCLUSION: Kedo-S pediatric rotary system showed significantly better cleaning than ProTaper rotary system and K files in cleaning primary molar root canals. CLINICAL RELEVANCE: The anatomy and morphology of primary teeth demand a specialized file system that will overcome the shortcomings of conventional biomechanical preparation. Kedo-S files, being exclusive pediatric rotary files, might prove to be a boon in primary canal preparation. HOW TO CITE THIS ARTICLE: Kalita S, Agarwal N, Jabin Z, et al. Comparative Evaluation of Cleaning Capacity and Efficiency of Kedo-S Pediatric Rotary Files, Rotary ProTaper, and Hand K Files in Primary Molar Pulpectomy. Int J Clin Pediatr Dent 2021;14(3):383-387.

Quantitative Analysis and Effect of SDF, APF, NaF on Demineralized Human Primary Enamel Using SEM, XRD, and FTIR.

INTRODUCTION: Topical fluoride therapy has proven benefits in the prevention of demineralization. Tooth enamel has shown a great potential for remineralization with an application of topical fluorides if administered at an appropriate time. In an effort to find an effective remineralizing agent, a novel fluoride agent silver diamine fluoride (SDF) has emerged as a potent caries arresting as well as caries preventing agent. AIM AND OBJECTIVE: The present study was aimed at determining the primary tooth enamel resistance to demineralization after topical application of three fluoride agents SDF, APF, and NaF. MATERIALS AND METHODS: Enamel specimens were prepared from 40 caries-free primary molars. These specimens were randomly allocated into three groups of 10 specimens each and they were treated by different topical fluorides namely: Group I-SDF, group II-Acidulated phosphate fluoride (APF), group III-Sodium fluoride. Three enamel specimens from each group were placed on custom-made acrylic blocks with 5 × 5 mm of an exposed window for scanning electron microscope (SEM) evaluation and rest of the specimens were ground into a fine powder for X-ray diffraction (XRD) and Fourier transform infrared spectroscopy (FTIR) analysis. The tooth blocks and treated samples were subjected to the demineralization process for 168 hours. They were then qualitatively assessed to evaluate their resistance to demineralization using SEM, XRD, and FTIR. RESULTS AND CONCLUSION: Morphologically, the enamel of all groups specimens was mostly smooth with some groves and microporosities. Chemically, the Ca/P molar ratios of all groups were similar with slight variations. Structurally, the crystalline phases found in enamel by powder XRD were hydroxyapatite and carbonate apatite; and there was a higher amount of incorporated type B carbonate than type A carbonate as evidenced by FTIR. The study concludes that topical application of a 38% SDF solution can inhibit demineralization of enamel. HOW TO CITE THIS ARTICLE: Jabin Z, Nasim I, Vishnu Priya V, et al. Quantitative Analysis and Effect of SDF, APF, NaF on Demineralized Human Primary Enamel Using SEM, XRD, and FTIR. Int J Clin Pediatr Dent 2021;14(4):537-541.

Known data on the effectiveness of silver nano particles on root canal disinfection.

The goal of endodontic treatment is the debridement and removal of the microbial ecosystem associated with the disease process. The need for root canal disinfectants increases especially in those cases where infection is resistant to the regular treatment and the outcome of endodontic therapy is often compromised. Therefore, it is of interest to document the known effectiveness of silver nanoparticle based root canal disinfectants with other root canal disinfectants on microbial load reduction during root canal disinfection. Known data shows that the overall risk of bias for the selected studies was moderate. Silver nanoparticle based root canal disinfectants showed superior reduction of microbial counts in majority of the studies. This data is limited to vitro studies with no clinical information to validate the use of antimicrobial properties of silver nanoparticles used as root canal disinfectant.

Cross-cultural adaptation and psychometric properties of the Hindi version of Child Perception Questionnaire (CPQ11-14 ) in school children.

BACKGROUND: There is a need to validate OHRQoL measures in Hindi to assess the OHRQoL of Indian children. AIM: To develop a Hindi version of the CPQ11-14 and to appraise its validity and reliability for use among North Indian children aged 11-14 years. DESIGN: The cross-culturally adapted Hindi version of CPQ11-14 was achieved by forward translation, backward translation, committee review, and pretesting. A total of 1000 children were recruited from schools, chosen by two-stage cluster random sampling technique. After completing the self-administered questionnaire CPQ11-14 by the child, oral examination was conducted using decayed/missing/filled teeth (DMFT) index, malocclusion index, and Dean's fluorosis index. Test-retest reliability was checked on 100 participants after one week. RESULTS: The floor effect was present in 3.6% individuals, and there was no ceiling effect. Cronbach's alpha for the overall CPQ11-14 scale was 0.963. Intra-class correlation (ICC) coefficient was 0.952 for the entire scale. Cronbach's alpha value for test-retest was 0.918. There was a non-significant change in domain-level and overall median CPQ11-14 scores with an increase in DMFT scores. For malocclusion and fluorosis, there was a statistically significant increase in overall and domain-level scores with increased severity scores. CPQ11-14 and individual domains significantly correlated with both the global questions. CONCLUSION: Hindi version of CPQ11-14 is a reliable scale to assess OHRQoL in Hindi speaking 11- to 14-year-old children.

Effect of 38% silver diamine fluoride on control of dental caries in primary dentition: A Systematic review.

Silver diamine fluoride (SDF) has been extensively researched and proven effective for caries prevention and arrest in children. Limited studies support its effectiveness in primary dentition at 38%. This systematic review examines the effectiveness of 38% silver diamine fluoride on control of dental caries in primary dentition. Multiple search engines and databases were searched in accordance with predefined inclusion-exclusion criteria. Quality assessment was done using Centre for Evidence-Based Medicine worksheets. Scientific works of literature were searched in October 2019 for articles. Four studies were identified that addressed the effectiveness of 38% SDF on deciduous dentition in children. All the four studies selected were controlled clinical trials. The cumulative results of the studies showed that 38% SDF application is efficacious and safe for the control of dental caries in primary teeth. Its advantages over different other techniques or placebo have been demonstrated. Based on this systematic review, 38% SDF is one of the best treatment approaches in control of dental caries in primary dentition.

Cytotoxicity and anti-microbial analysis of silver and graphene oxide bio nanoparticles.

It is of interest to document the cytotoxicity and anti microbial analysis of silver and graphene oxide nanoparticles. The plant extracts from Andrographis paniculata and Ocimum sanctum Linn were used as reducing agent. The nanoparticles were characterized using UV-visible spectroscopy, FT-IR, XRD and TEM. The antimicrobial activity was completed for oral pathogens. Brine Shrimp Lethality assay was conducted for cytotoxicity. Thus, we show that silver and graphene oxide bio based nanoparticles have antimicrobial activity with minimum cytotoxic effects.