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1.
Sci Rep ; 12(1): 15584, 2022 Sep 16.
Artigo em Inglês | MEDLINE | ID: mdl-36114411

RESUMO

In this study, a novel synthetic method for cobalt oxide (Co3O4) nanoparticles using Bos taurus (A-2) urine as a reducing agent was developed. In addition to this ZnO nanorods were produced hydrothermally and a nanocomposite is formed through a solid-state reaction. The synthesized materials were characterized through modern characterization techniques such as XRD, FE-SEM with EDS, DLS, zeta potential, FT-IR, Raman spectroscopic analysis, and TGA with DSC. The free radical destructive activity was determined using two different methods viz. ABTS and DPPH. The potential for BSA denaturation in vitro, which is measured in comparison to heat-induced denaturation of egg albumin and results in anti-inflammatory effects of nanomaterial was studied. All synthesized nanomaterials have excellent antibacterial properties, particularly against Salmonella typhi and Staphylococcus aureus. The composite exhibits excellent antioxidant and anti-inflammatory activities in comparison to pure nanomaterials. This reveals that these nanomaterials are advantageous in medicine and drug administration.


Assuntos
Óxido de Zinco , Albuminas , Animais , Antibacterianos/química , Antibacterianos/farmacologia , Antioxidantes/farmacologia , Bovinos , Cobalto , Óxidos , Substâncias Redutoras , Espectroscopia de Infravermelho com Transformada de Fourier , Difração de Raios X , Óxido de Zinco/química , Óxido de Zinco/farmacologia
2.
Appl Nanosci ; 12(7): 2207-2226, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35466324

RESUMO

In this study, we are reporting biogenic synthesis of silver nanoparticles and hydrothermal synthesis of zinc oxide nanoparticles. Using convenient mechanical milling methods, nanocomposites with superior photocatalytic and catalytic properties are synthesized. Herein, we have adopted a green, eco-friendly, and economical route for the synthesis of Ag nanoparticles using Zingiber officinalae rhizome extract in an aqueous solution. The synthesized materials were characterized using UV-Vis spectroscopy, XRD, SEM & FE-SEM, FT-IR, Raman, and a particle size analyzer with zeta potential analysis. The photocatalytic activities of Ag, ZnO and their composites were studied by observing the degradation of methylene blue and crystal violet dyes under natural sunlight. Then the catalytic efficacies of synthesized nanoparticles for various organic transformation reactions were studied. Ag-ZnO nanocomposites were predicted to have improved photocatalytic activity and organic transformation reactions, allowing them to be used in environmental remediation applications.

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