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J Minim Invasive Gynecol ; 23(3): 396-403, 2016.
Artigo em Inglês | MEDLINE | ID: mdl-26723571

RESUMO

STUDY OBJECTIVE: To show the feasibility, technique, and results of laparoscopic anterior exenteration in selected patients. DESIGN: A retrospective cohort study. SETTING: Galaxy Care Laparoscopy Institute, Pune, India. PATIENTS: Seventy-four of 85 patients who underwent laparoscopic anterior exenteration for stage IVA carcinoma of the cervix from January 2005 to January 2015 were analyzed; the median follow-up was 30 months. Contrast-enhanced computed tomographic imaging of the abdomen and pelvis was performed for all patients. INTERVENTIONS: The same surgeon and team performed all the operations for uniformity in 10 operative steps. MEASUREMENTS AND MAIN RESULTS: The mean operative time was 180 minutes, and the mean blood loss was 160 mL. The mean hospital stay was 6 days. The average number of lymph nodes removed was 21.4. Surgical margins were negative in all patients. Forty-two patients had positive lymph nodes. Chemoradiation was given to those with positive lymph nodes. Perioperative complications occurred in 15 (20.27%) patients including deep vein thrombosis, urinary tract infection, ureterosigmoid leak (n = 2/74), and so on. Positron emission tomographic imaging and computed tomographic scanning were performed at 6 months after surgery and 6 months after adjuvant therapy in those with positive lymph nodes. There was no immediate postoperative mortality. The overall survival rate at 5 years was 25%. CONCLUSION: Laparoscopic anterior exenteration is feasible in cases of advanced carcinoma of the cervix. Results have shown that in selected patients this procedure is associated with good long-term survival.


Assuntos
Carcinoma/cirurgia , Laparoscopia , Excisão de Linfonodo , Linfonodos/patologia , Exenteração Pélvica , Neoplasias do Colo do Útero/cirurgia , Adulto , Idoso , Carcinoma/mortalidade , Carcinoma/patologia , Quimiorradioterapia Adjuvante , Estudos de Viabilidade , Feminino , Seguimentos , Humanos , Índia/epidemiologia , Laparoscopia/métodos , Masculino , Pessoa de Meia-Idade , Exenteração Pélvica/instrumentação , Exenteração Pélvica/métodos , Tomografia por Emissão de Pósitrons , Estudos Retrospectivos , Análise de Sobrevida , Tomografia Computadorizada por Raios X , Resultado do Tratamento , Neoplasias do Colo do Útero/mortalidade , Neoplasias do Colo do Útero/patologia
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