Eyelid edema as a first sign of lymphoma.

Chronic eyelid edema may be a symptom of different disease. The most common are autoimmune diseases such as orbital pseudotumor, vasculitis, sarcoidosis, or impaired vascular or lymphatic drainage. Rarely has it been reported as the sole manifestation of the lymphoma. Eyelid lymphoma is a special clinical entity in the spectrum of hematological malignancies. Here we present our clinical experience with eyelids lymphomas. First case is a 76-year-old female patient with bilateral edema of upper eyelid non-responding to anti-inflammatory therapy. Histological examination diagnosed mantle cells lymphoma. In the second case, 58-year-old patient was diagnosed with solitary unilateral tumor of the lower eyelid, where primary biopsy was ordered and diagnosis of MALT lymphoma was established after histological examination. In both cases, it was not solitary eyelid tumor, but systemic disease with multiple lymphadenopathy and bone marrow infiltration were found in follow-up examinations. Subsequently, patients care was given to the hemato-oncologist.

[Frosted branch angiitis syndrome]. / Syndróm omrznutých vetiev retinálnych ciev.

The authors present a case report of a 20-year-old patient with an atypical clinical picture of bilateral vasculitis associated with bilateral macular oedema and decrease in visual acuity. On basis of the clinical picture, frosted branch angiitis was diagnosed. The patient was instructed to continue the broad-spectrum antibiotic therapy prescribed by an ophthalmic practitioner of the appropriate catchment area. The visual acuity progressively improved and after application of systemic corticosteroid therapy the patients health state improved completely. According to the authors knowledge, this is the first diagnosed case of frosted branch angiitis in the Slovak Republic.