Long-term MRI findings in operated rotator cuff tear.

PURPOSE: To describe magnetic resonance imaging (MRI) findings at long-term follow-up after rotator cuff (RC) tear using standard MRI sequences without fat saturation. MATERIAL AND METHODS: Twenty-eight patients aged 55.8+/-7.6 underwent MRI examination 4.6+/-2.1 years after surgery for RC tear. Standard sequences in oblique coronal, oblique sagittal, and axial planes were obtained. The RC, including re-tears and tendon degeneration, was independently evaluated by two observers. Thickness of the supraspinatus tendon and narrowing of the subacromial space were measured. The clinical outcome was evaluated with the Constant score and compared with the MRI findings. RESULTS: The RC tear was traumatic in 18 (64%) patients and degenerative in 10 (36%). At follow-up, 11 (39%) had normal RC tendons with good clinical outcome. Four (14%) patients had painful tendinosis without RC tear. A full-thickness RC tear was found in 7 (25%) patients and a partial tear in 6 (21%). In one patient with a full-thickness tear, and in two with partial tear, tendinosis was found in another of the RC tendons. The subacromial space was narrowed in 13 (46%) of the patients. A narrowing of the subacromial space correlated with re-tear (P<0.05). CONCLUSIONS: The RC may be evaluated with standard MRI sequences without fat saturation at long-term follow-up. A normal appearance of the RC is correlated with good clinical outcome, while re-tear and tendinosis are associated with pain.

Markers of cartilage and synovial metabolism in joint fluid and serum of patients with chondromalacia of the patella.

OBJECTIVE: To further our understanding of the pathogenesis of chondromalacia of the patella (CM), we have studied the release into knee joint fluid and serum, obtained from patients with CM, of molecules associated with the metabolism of joint cartilage matrix and synovium. METHODS: Interleukin-1 alpha (IL-1 alpha), interleukin-1 beta (IL-1 beta), interleukin-6 (IL-6), stromelysin-1 (MMP-3), interstitial collagenase (MMP-1), tissue inhibitor for metalloproteinases-1 (TIMP-1), phospholipase activity A2 (PLA2), hyaluronan (HA), aggrecan fragments (AGN) and antigenic keratan sulfate (KS) were quantified in knee joint lavage fluid from 96 patients with CM; KS and HA also was measured in serum. Chondromalacia was graded on a scale of I to IV according to Outerbridge (1961). The histopathology of the synovial membrane close to the patellofemoral joint was evaluated. Control samples were obtained from nine patients with knee pain presenting with arthroscopically normal knee joints. RESULTS: The concentrations of MMP-3, MMP-1 and TIMP-1 proteins in joint lavage fluid were increased in advanced (grade IV) CM, compared with controls. Levels of MMP-1 in lavage fluid correlated with the severity of CM (r = 0.38, P < 0.01) and MMP-1 and MMP-3 concentrations correlated with each other (r = 0.45, P < 0.001). TIMP-1 was elevated in grade IV CM compared with grades II and III CM (P < 0.02, P < 0.01). Interleukins (IL-1 alpha, IL-1 beta and IL-6) showed no significant change in CM. The lavage fluid level of PLA2 increased with the severity of CM (r = 0.40, P < 0.001). Serum KS was higher in CM IV than in controls (P = 0.05), while lavage fluid KS concentration was elevated in CM I (P = 0.04). There were no differences in the lavage fluid levels of AGN and HA between the different study groups. Synovium showed slight or moderate histological signs of inflammation in 9% of CM patients. CONCLUSION: The changes in the release and activity of these marker molecules from serum and synovial fluid may reflect changes in the metabolism of articular cartilage and synovium in CM, that are consistent with those observed in early-stage tibiofemoral cartilage changes in OA.

Collagen crosslinks in chondromalacia of the patella.

The aim of the study was to determine collagen concentration and collagen crosslinks in cartilage samples from chondromalacia of the patella. To study the extracellular matrix alterations associated to chondromalacia, we determined the concentration of collagen (hydroxyproline) and its hydroxylysylpyridinoline and lysylpyridinoline crosslinks from chondromalacia foci of the patellae in 12 patients and 7 controls from apparently normal cadavers. The structure of the collagen network in 8 samples of grades II-IV chondromalacia was examined under polarized light microscopy. The full-thickness cartilage samples taken with a surgical knife from chondromalacia lesions did not show changes in collagen, hydroxylysylpyridinoline and lysylpyridinoline concentration as compared with the controls. Polarized light microscopy showed decreased birefringence in the superficial cartilage of chondromalacia lesions, indicating disorganization or disappearance of collagen fibers in this zone. It is concluded that the collagen network shows gradual disorganization with the severity of chondromalacia lesion of the patella without changes in the concentration or crosslinks of collagen.

Rotator cuff calcifications: treatment with ultrasound-guided percutaneous needle aspiration and lavage.

OBJECTIVE: To analyze the results of ultrasound (US)-guided needle puncture, aspiration and lavage in the treatment of symptomatic calcific tendinitis of the rotator cuff. DESIGN AND PATIENTS: Atraumatic pain in 61 shoulders of 58 patients was resistant to conservative therapy. The average age of the treated patients was 42 years (range 26-49 years), follow-up was 12 months, and the mean diameter of the calcifications was 1.6 cm (range 1.1-2.9 cm). With US guidance and local anesthesia, two needles were placed within each calcification. The calcification was punctured 10-15 times and saline solution injected and aspirated using the needles until the aspirate was free of calcific particles. RESULTS AND CONCLUSIONS: Based on radiographs at 1 year follow-up. 74% (45 of 61) of the calcifications decreased, including 28% (17 of 61) which disappeared totally, and 26% (16 of 61) were unchanged. Calcifications with a faint or absent shadow on US proved to be nearly liquid (slurry calcification in 93% (14 of 15) of cases and could be aspirated. Clinical results were excellent in 74% (45 of 61), moderate in 16% (10 of 61) and poor in 10% (6 of 61) of cases. US offers technical advantages over fluoroscopy, and the typical US image of a slurry calcification helps to select the most suitable patients for aspiration treatment. The results are comparable with those using fluoroscopic guidance.

Hill-Sachs lesion: sonographic detection.

OBJECTIVE: To determine the value of ultrasonography (US) in the detection of Hill-Sachs lesion of the humerus in comparison with double-contrast computed tomographic arthrography (CTA) and with arthroscopy. DESIGN AND PATIENTS: US and CTA were performed on 92 patients, 86 of whom subsequently underwent arthroscopy. The findings of US, CTA and arthroscopy in these 86 patients in the diagnosis of Hill-Sachs lesion were analyzed. RESULTS AND CONCLUSIONS: In the detection of Hill-Sachs lesion US showed a sensitivity of 91% (21 of 23), a specificity of 95% (60 of 63) and an accuracy of 94% (81 of 86) when compared with CTA, and a sensitivity of 94% (18 of 19), specificity of 91% (61 of 67) and accuracy of 91% (79 of 86) when compared with arthroscopy. In only 2% (2 of 86) of patients was there reduced visualization because of restriction of movement. Hill-Sachs lesion and its relationship to the humeral head can be reliably diagnosed with US.

Site and size of rotator-cuff tear. Findings at ultrasound, double-contrast arthrography, and computed tomography arthrography with surgical correlation.

RATIONALE AND OBJECTIVES: The authors discuss findings of ultrasound (US), double-contrast arthrography (AG), and contrast computed tomography arthrography (CTA) in assessing precise site and size of rotator-cuff tears. METHODS: Eighty-six patients were compared prospectively in a masked fashion; the results of surgery were studied in 25 patients and the results of arthroscopy were studied in 61 patients. RESULTS: Ultrasound detected 80% (8 of 10) of the partial-thickness tears and 90% (18 of 20) of the full-thickness tears. Arthrography and CTA had identical results with 70% sensitivity (7 of 10) in partial-thickness tears; AG showed 90% (18 of 20) and CTA 95% (19 of 20) of the full-thickness tears. Arthrography had two false-positive findings, and US and CTA had one each. The size of a tear could be evaluated correctly with AG in 30% (9 of 30), with US in 70% (21 of 30) and with CTA in 76% (23 of 30). More extensive tears were encountered at US than had been found at surgery in 2% (2 of 86) and less extensive tears in 9% (8 of 86); CTA depicted more extensive tears in 2% (2 of 86) and less extensive tears in 6% (6 of 86), respectively. The site of a tear could be evaluated with AG in 30% (9 of 30); US and CTA showed the site correctly in every patient in which the tear could be diagnosed. CONCLUSION: Ultrasound and CTA were equally accurate in diagnosing and evaluating the size and site of rotator-cuff tears. Double-contrast AG was less accurate in the diagnosis of tears and the size and site of tears clearly could be assessed worse.

The bicipital groove of the humerus: sonographic and radiographic correlation.

OBJECTIVE: The objective of this study was to compare ultrasonography (US) and plain radiography in the evaluation of the bicipital groove of the humerus and to determine the accuracy of US in measurement of the width and depth of the groove compared to plain radiography. PATIENTS AND METHODS: Visualization of the groove and its abnormalities in 350 consecutive patients by US and on tangential groove radiographs were compared. The groove was measured prospectively in 45 patients on the ultrasound imaging monitor and retrospectively on groove radiographs without knowledge of the US results. RESULTS: The bony anatomy of the groove was adequately seen with US in 90% of patients (314 of 350) and on groove radiographs in 91% (319 of 350). All 24 shallow and 6 tunnel-shaped grooves were diagnosed with both imaging methods, but osteophytes and erosions could not be reliably demonstrated with US. CONCLUSION: Sonography was as accurate for evaluation of the dimensions of the bicipital groove as groove radiographs, and both methods had a similar failure rate. Pathological changes of the walls of the groove could not be reliably evaluated with sonography.

Sonographic detection of tears of the anterior portion of the rotator cuff (subscapularis tendon tears).

We studied the value of ultrasonography in identifying tears of the most anterior portion of the rotator cuff (subscapularis tendon tears). Shoulder sonography was performed on 1640 patients with shoulder symptoms, 435 of whom underwent surgery. Among the patients who were operated on, 17 had predominantly or exclusively subscapularis tendon tears; 14 of these were full-thickness and three were partial-thickness tears. Ultrasonography demonstrated 82% (14 of 17) of the subscapularis tendon tears; 86% (12 of 14) of the full-thickness tears and 67% (2 of 3) of the partial-thickness tears were correctly diagnosed with ultrasonography. Sonography can diagnose and show the size of subscapularis tendon tears reliably, but it necessitates that the arm can be externally rotated to the maximum extent when performing the study.

Prevention of fatal pulmonary embolism with warfarin after total hip replacement.

We studied retrospectively the efficacy of low-dose warfarin for the prevention of fatal pulmonary embolism in 1140 patients (1280 hips) undergoing total hip replacement between 1972 and 1989. The first dose, 10-20 mg, was given the night before operation and the regime was continued for 2 weeks after the procedure. Anticoagulation was aimed at achieving a therapeutic level in 4 to 5 days. All the patients were followed for 3 months. Seven died during this period and autopsy showed that 2 (0.16%) died from pulmonary embolism, one at 3 days and the other 10 days after operation. Pulmonary embolism causing symptoms, but which was not fatal, occurred in 32 patients (2.5%). Symptomatic deep vein thrombosis was present in 45 patients (3.5%). There were 14 (1.1%) massive postoperative haematoma, and 7 needed operative treatment. Low-dose warfarin can be recommended as a safe and efficient method of achieving an acceptably low incidence of postoperative thrombo-embolic complications after total hip replacement.

Acute traumatic tears of the rotator cuff: value of sonography.

PURPOSE: To determine the value of sonography in the evaluation of acute traumatic tears of the rotator cuff. MATERIALS AND METHODS: Preoperative sonography was performed within 3 weeks of trauma in 184 patients, 98 of whom underwent surgery. The rotator cuff tears were preoperatively classified as partial-thickness tears or as small, large, or massive full-thickness tears. Sonographic findings were correlated with surgical findings (n = 70) and arthroscopic inspection (n = 28). RESULTS: Adequate examination was possible in 163 (88%) of 184 patients. Sonography demonstrated 42 (91%) of 46 full-thickness tears and seven (78%) of nine partial-thickness tears. Sonography showed more extensive tears than were found at surgery in four (4%) of 98 patients and less extensive tears in seven (7%) of 98 patients. Sonographic patterns were a defect (31 [63%] of 49 tears), focal thinning (10 [21%] of 49 tears), and nonvisualization (eight [16%] of 49 tears). CONCLUSION: Sonography is useful in the evaluation of acute shoulder trauma when a rotator cuff tear is suspected and findings at plain radiography are negative.

Proteoglycan depletion and size reduction in lesions of early grade chondromalacia of the patella.

OBJECTIVE: To determine the content and molecular size of proteoglycans (PGs) in patellar chondromalacia (CM) and control cartilages as a first step in investigating the role of matrix alterations in the pathogenesis of this disease. METHODS: Chondromalacia tissue from 10 patients was removed with a surgical knife. Using identical techniques, apparently healthy cartilage of the same site was obtained from 10 age matched cadavers (mean age 31 years in both groups). Additional pathological cartilage was collected from 67 patients with grades II-IV CM (classified according to Outerbridge) using a motorised shaver under arthroscopic control. The shaved cartilage chips were collected with a dense net from the irrigation fluid of the shaver. The content of tissue PGs was determined by Safranin O precipitation or uronic acid content, and the molecular size by mobility on agarose gel electrophoresis. RESULTS: The mean PG content of the CM tissue samples with a knife was dramatically reduced, being only 15% of that in controls. The cartilage chips collected from shaving operations of grades II, III, and IV CM showed a decreasing PG content: 9%, 5%, and 1% of controls, respectively. Electrophoretic analysis of PGs extracted with guanidium chloride from the shaved tissue samples suggested a significantly reduced size of aggrecans in the mild (grade II) lesions. CONCLUSION: These data show that there is already a dramatic and progressive depletion of PGs in CM grade II lesions. This explains the softening of cartilage, a typical finding in the arthroscopic examination of CM. The PG size reduction observed in grade II implicates proteolytic attack as a factor in the pathogenesis of CM.

Digital subtraction shoulder arthrography in determining site and size of rotator cuff tear.

RATIONALE AND OBJECTIVES: To evaluate the value of digital subtraction arthrographic techniques in assessing the precise size and site of rotator cuff tear. PATIENTS AND METHODS: Prospectively interpreted findings of 29 digital arthrographs were compared with results after surgery in 22 patients and with results after arthroscopy in 7 patients. RESULTS: Surgery or arthroscopy revealed 14 full-thickness and 2 partial-thickness tears. Digital subtraction arthrography showed 88% (14 of 16) of the rotator cuff tears, 86% (12 of 14) of the full-thickness tears, and 100% (2 of 2) of the partial-thickness tears. The site of a tear could be shown in 86% (12 of 14), but the size was evaluated to be less extensive than that seen at surgery in most tears (63%, 10 of 16). CONCLUSIONS: The site of tears could be demonstrated in supraspinatus tendon tears, but measurements of the size of the tears were accurate only in small full-thickness and in partial-thickness tears. Very anterior and posterior tears may not be diagnosed with this method, and postexercise films were necessary to avoid false-negative findings.

Rotator cuff calcifications: treatment with US-guided technique.

PURPOSE: The authors developed and tested a technique to treat calcific tendinitis in the rotator cuff with multiple needle punctures, aspiration, and lavage under ultrasonographic (US) guidance. MATERIALS AND METHODS: Atraumatic pain in the shoulders of a 46-year-old woman and a 42-year-old man was resistant to conservative therapy. With local anesthesia and continuous three-dimensional US visualization, the tips of two 18-gauge needles were placed within the calcification in the rotator cuff. Saline solution was injected and aspirated with the needles until the aspirate was free of calcific particles. RESULTS: Both patients experienced complete relief of pain and recovery of full range of motion, one on the 3rd day after treatment and one within 15 minutes. CONCLUSION: Use of this US-guided technique is successful to treat calcific tendinitis in the rotator cuff without the radiation exposure of fluoroscopic guidance.

Medial displacement of the biceps brachii tendon: evaluation with dynamic sonography during maximal external shoulder rotation.

PURPOSE: To determine the value of the sonographic subluxation test--dynamic scanning of a shoulder during maximal external rotation--in the evaluation of medial displacement of the biceps tendon. MATERIALS AND METHODS: The subluxation test was performed during shoulder sonography in 1,210 patients, 284 of whom subsequently underwent surgery (152 men and 132 women aged 24-77 years [mean, 52 years]). Subluxation or displacement of the biceps tendon was surgically confirmed in 21 of the 284 patients (16 men and five women aged 35-57 years [mean, 48 years]). The sonographic and surgical findings in these 21 patients were analyzed. RESULTS: The subluxation test helped detect 12 of 14 (86%) cases of subluxation. Static scanning (without the subluxation test) depicted six of seven (86%) cases of dislocation. The test failed or could not be performed in 18 of the 284 (6%) patients; however, no false-positive findings occurred. CONCLUSION: The subluxation test is reliable in the diagnosis of subluxation of the biceps tendon and should be performed during shoulder sonography.

Sonographic findings of rotator cuff calcifications.

We studied the findings and value of sonography in the diagnosis of rotator cuff calcifications in comparison to plain radiographs. Sonograms were correlated with plain radiographs in 951 patients. The diagnosis of rotator cuff calcifications was made by ultrasonography in 87 and with plain films in 93 of 951 patients. Sonography displayed two additional bursal slurry calcifications were found on plain films. Three types of calcifications were found with ultrasonography: (1) a hyperechoic focus with a well-defined shadow (79%); (2) a hyperechoic focus with a faint shadow (14%); and, (3) a hyperechoic focus with no shadow (7%). Large and slurry calcifications and bursal calcifications were better seen with ultrasonography, but small and more scattered deposits were better found on plain radiographs. Sonography proved to be reliable in the detection and localization of rotator cuff calcifications, but classification into a formative or resorptive phase could not be done. Because of this and the possibility of pathologic conditions of bone, plain radiographs should always be obtained prior to doing sonography.

Decreased torque and electromyographic activity in the extensor thigh muscles in chondromalacia patellae.

The alterations in thigh muscle properties of chondromalacia patellae patients during isometric and dynamic endurance tests were studied using a variokinetic knee testing system linked to surface EMG. A total of 41 patients (chondromalacia group) with arthroscopically certified chondromalacia of the patella were studied. The control group consisted of 31 healthy adult volunteers with no history of knee pain or trauma. Peak torque values were 21% (p < 0.01) and force output values 25% (p < 0.05) lower on the symptomatic side of the chondromalacia group than in the control group. The decrease in the ratio between integrated EMG (IEMG) and measured force were found in all parts of the quadriceps femoris muscle in patients with chondromalacia of the patella in isometric extension. No change in the normalized IEMG levels of the thigh muscles were found between chondromalacia patients and controls in dynamic endurance test. The severity of the chondromalacia of the patella did not affect the level of electromyographic activation in thigh muscles. The ratio of normalized EMG levels of vastus medialis and vastus lateralis did not differ between the groups. The present study showed that chondromalacia patellae patients have reduced force and electromyographic activation levels of quadriceps femoris muscle. Especially, the explosive strength of the quadriceps femoris muscle is reduced.

Lateral release in chondromalacia patellae using clinical, radiologic, electromyographic, and muscle force testing evaluation.

Lateral release (division of the lateral retinaculum of the patella) is a common operative procedure to improve alignment of the patella in patients with chondromalacia patellae. We investigated the effects of lateral release using clinical follow-up and studied the changes in the radiologic measurements of the patellar alignment and electromyographic function of the stabilizing muscles of the knee, as well as using muscle-force tests of the thigh. The study included 75 patients. Diagnostic arthroscopy was done for all patients. In 42 patients with obvious incongruency of the patellofemoral joint observed at arthroscopy, open division of the lateral patellar retinaculum was performed in addition to arthroscopy. Four years after surgery, the results showed that although division of the lateral retinaculum of the patella reduced lateral patellar tilting and lateral patellar displacement, the postoperative physical capacity of the patients was not improved. Lateral release did not impair the electrical activity of thigh muscles. The Lysholm scores of the lateral release group and the control group were equal after four years.

Periosteal and perichondral grafting in reconstructive surgery.

Periosteum consists of multipotent mesodermal cells, and the influence of the environment on differentiation of cells of free periosteal grafts has been demonstrated in experimental studies. Periosteum has the capacity to form all varieties of connective tissue. The periosteum has osteogenic capacity, but it can also be used to promote cartilage formation in a chondrotrophic environment. Free periosteal grafts transplanted to the completely chondrectomized articular surfaces of patellae in experimental animals differentiated into cartilage. Joint motion appeared to be one of the chondrogenesis-promoting factors. The authors are optimistic about the potential clinical results with these types of grafts. Also, periosteal resurfacing of the metatarsal head was found to be suitable in the treatment of hallux rigidus and Freiberg's disease. Findings in growing rabbits showed that spinal fusion can be achieved with free periosteal grafts. This technique has been used to treat lumbar lytic spondylolisthesis in young patients, and the method produced clinical and radiologic results that were comparable with those obtained using bone transplants. This work indicates that some of the adverse effects of lumbar spinal fusion (e.g., postoperative spinal stenosis) can be avoided by using osteoperiosteal fusion. Also, periosteal grafting has proved useful in the treatment of thoracolumbar scoliosis. Free periosteal grafting has been used to treat congenital clefts of the maxilla and tracheal cartilage defects.

Dupuytren's contracture: the long-term results after day surgery.

220 operations in 211 hands in 160 consecutive patients suffering from Dupuytren's contracture were performed from 1976 through 1984 at the Kuopio University Central Hospital in Finland. 179 operations were carried out as day cases. The mean follow-up was 3.2 years. Sub-total fasciectomy resulted in good immediate and long-term improvement in 86% of patients. The recurrence rate was 27%. Surgical treatment of Dupuytren's contracture was well-suited to day surgery. A properly planned follow-up programme is suggested because of the relatively high rate of recurrence, which usually appeared within two years after operation.

[The sonography of rotator cuff ruptures. The correlation of the sonographic, arthrographic and intraoperative findings in rotator cuff ruptures]. / Sonographie der Rotatorenmanschettenruptur. Korrelation sonographischer, arthrographischer und intraoperativer Befunde bei Rotatorenmanschettenrupturen.

We have compared the findings of sonography, arthrography and at surgery in 66 cases of rotator cuff rupture in order to clarify the sonographic and radiological signs. Preoperative sonography was better than arthrography at demonstrating a partial rupture and at showing the extent of the lesion.