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1.
Sci Rep ; 10(1): 5084, 2020 Mar 19.
Artigo em Inglês | MEDLINE | ID: mdl-32193448

RESUMO

An amendment to this paper has been published and can be accessed via a link at the top of the paper.

2.
Sci Rep ; 10(1): 215, 2020 Jan 14.
Artigo em Inglês | MEDLINE | ID: mdl-31937804

RESUMO

The stability of the hydrogen molecule interacting with the environment according to the balanced gain and loss energy scheme was studied. We determined the properties of the molecule taking into account all electronic interactions, the parameters of the Hamiltonian being computed by the variational method. The interaction of the hydrogen molecule with the environment was modeled parametrically (γ) by means of the non-Hermitian, [Formula: see text]-symmetric Hamiltonian. We showed that the hydrogen molecule is dynamically unstable. Its dissociation time (TD) decreases if the γ parameter increases (for γ → 0 we got TD → + ∞). The dynamic instability of the hydrogen molecule is superimposed on the decrease in its static stability as γ increases. Then we can observe the decrease in the dissociation energy value and the existence of the metastable state of the molecule as γMS reaches 0.659374 Ry. The hydrogen molecule is statically unstable when γ > γD = 1.024638 Ry. Moreover, we can also observe the [Formula: see text] symmetry breaking effect for the electronic Hamiltonian when [Formula: see text] = 0.520873 Ry. This effect does not affect such properties of the hydrogen molecule as: the electronic Hamiltonian parameters, the phonon and the rotational energies, and the values of the electron-phonon coupling constants neither it disturbs the dynamics of the electronic subsystem. However, the number of available quantum states goes down to four.

3.
Cereb Cortex ; 29(9): 3666-3675, 2019 08 14.
Artigo em Inglês | MEDLINE | ID: mdl-30272136

RESUMO

We have previously reported that the blockage of TrkB and TrkC signaling in primary culture of opossum neocortical cells affects neurogenesis that involves a range of processes including cell proliferation, differentiation, and survival. Here, we studied whether TrkB and TrkC activity specifically affects various types of progenitor cell populations during neocortex formation in the Monodelphis opossum in vivo. We found that the inhibition of TrkB and TrkC activities affects the same proliferative cellular phenotype, but TrkC causes more pronounced changes in the rate of cell divisions. Additionally, inhibition of TrkB and TrkC does not affect apoptosis in vivo, which was found in cell culture experiments. The lack of TrkB and TrkC receptor activity caused the arrest of newly generated neurons; therefore, they could not penetrate the subplate zone. We suggest that at this time point in development, migration consists of 2 steps. During the initial step, neurons migrate and reach the base of the subplate, whereas during the next step the migration of neurons to their final position is regulated by TrkB or TrkC signaling.


Assuntos
Monodelphis/fisiologia , Neocórtex/fisiologia , Neurogênese , Neurônios/fisiologia , Receptor trkB/fisiologia , Receptor trkC/fisiologia , Animais , Diferenciação Celular , Movimento Celular , Proliferação de Células , Sobrevivência Celular , Feminino , Masculino , Transdução de Sinais
4.
Chaos ; 28(1): 013126, 2018 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-29390639

RESUMO

We have determined the stability conditions of the hydrogen molecule under the influence of an external force of harmonic-type explicitly dependent on the amplitude (A) and frequency (Ω). The ground state of the molecule has been determined in the framework of the Born-Oppenheimer approximation, whereas the energy of the electronic subsystem has been calculated using the Hubbard model including all two-site electron interactions. The diagram of RT0 (A,Ω), where RT0 denotes the distance between protons after the fixed initial time T0, allowed us to visualize the area of the instability with the complicated structure. We have shown that the vibrations of the hydrogen molecule have a chaotic nature for some points of the instability region. In addition to the amplitude and frequency of the extrusion, the control parameter of the stability of the molecule is the external force associated with pressure. The increase in its value causes the disappearance of the area of the instability and chaotic vibrations.

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