Mucosal Melanoma In Situ of the Oral Cavity: A Case Report and Systematic Review of the Literature.

Objective: Malignant mucosal melanomas of the head and neck comprise a very small portion of all melanomas, particularly in the oral cavity. These lesions are associated with high rates of local recurrence, distant metastasis, and a very poor 5-year survival rate; however, the clinical outcomes of mucosal melanoma in situ of the oral cavity are unclear. Therefore, we present a case report of mucosal melanoma in situ and a systematic review of the literature to shed light on this rare but important disease. Methods: PubMed, Scopus, and CINAHL were searched per the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Studies were only considered for inclusion if they described oral cavity melanoma in situ and documented specific data pertaining to treatment including modality, lesion size, or outcomes. Results: A total of 28 reported cases from the literature fulfilled the inclusion criteria, as well as one case from our own institution. Men comprised the majority (64.3%) of the cases, and the average age at presentation was 57.4 years. The hard palate was the most common location, and most cases were treated with surgical excision. Eight had no evidence of disease after a minimum of six months of follow-up, one reported spread to the cervical lymph nodes, and only one reported progression with distant metastasis. Conclusion: Oral mucosal melanoma in situ is a rare entity and most commonly treated with surgical excision. High rates of recurrence necessitate long term follow-up. Further studies may be useful to determine whether adjuvant therapy may play a role in reducing recurrence.

Video Analysis of Otologic Instrument Movement During Resident Mastoidectomies.

OBJECTIVE: To measure surgical instrument movement during resident mastoidectomies and identify metrics that correlate with experience. STUDY DESIGN: Retrospective case series. SETTING: Tertiary care center. SUBJECTS: Ten postgraduate year (PGY) 2, 6 PGY3, 7 PGY4, and 19 PGY5 recordings of mastoidectomy performed by otolaryngology residents. INTERVENTIONS: One-minute intraoperative recordings of mastoidectomies performed during cochlear implantation were collected. Drill and suction-irrigator motion were analyzed with sports motion tracking software. MAIN OUTCOME MEASURES: Mean instrument speed, angle, and angular velocity were calculated. Mann-Whitney U tests compared mean instrument metrics between PGY levels. Change in drill speed for seven residents between their PGY2 to PGY5 years was individually analyzed. RESULTS: Mean drill speed was significantly greater for PGY5 residents compared with PGY2s (2.9 versus 1.8 cm/s, p = 0.001). Compared with PGY2 residents, suction speed was greater as a PGY5 (1.2 versus 0.9 cm/s; p = 0.201) and significantly greater as a PGY4 (1.5 versus 0.9 cm/s, p = 0.039). Of the seven residents individually analyzed, group mean drill speed increased by 0.4 cm/s, yearly. CONCLUSIONS: Drill and suction-irrigator movement during the second minute of drilling of a cortical mastoidectomy seems to increase with resident level. Objective video analysis is a potential adjunct for differentiating novices from more experienced surgeons and monitoring surgical skills progress.

3-Dimensional Exoscope for Far Lateral Approach to Pontomedullary Cavernous Malformation.

Brainstem cavernous malformations account for 15%-18% of all central nervous system cavernomas and are histologically characterized by thin-walled, low-pressure capillaries, classically without intervening brain tissue.1,2 Cavernomas may be sporadic, typically characterized by a single lesion, or inherited. The inherited form is most often autosomal dominant with incomplete penetrance and variable expression. Multiple cavernomas are associated with the familial form; although this is not always the case, genetic workup should be pursued.3,4 Clinical presentation typically includes focal neurologic deficit related to hemorrhage location, seizures, and rarely obstructive hydrocephalus.1,2 Indications for surgical management include severe or progressive neurologic dysfunction, lesion size ≥2 cm, recurring hemorrhages, and/or significant mass effect.5 Microsurgical resection of a cavernoma is associated with an overall 28% complication rate and perioperative neurologic morbidity upwards of 45% according to some series. Long-term surgical outcomes at 12 months are more reassuring: 84% reported their condition to have improved or remained the same, and the long-term morbidity rate is 14%.1,6 The location of the lesion dictates the approaches available-cavernomas in the pons or medulla are commonly approached via a retrosigmoid or retrolabyrinthine approach, while more ventral pathologies in this region necessitate a far lateral approach.1,5,7,8 In Videos 1 and 2, we describe our experience with an exoscope-assisted far lateral approach to a pontomedullary cavernoma in a 10-year-old male presenting with numerous cavernomas and confirmed gene mutation. We demonstrate the exoscope's unparalleled visualization of the anterolateral brainstem, with nominal condylar drilling. The patient and his parents consented to the procedure and publication.