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Acta Med Iran ; 54(7): 471-4, 2016 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-27424020

RESUMO

We present a woman referred with underlying non-Hodgkin's lymphoma (NHL) masquerading clinically with Guillain-Barré syndrome (GBS) like syndrome. At first evaluation, chest CT-Scan along with brain and whole spine MRI were normal. Electrodiagnostic studies were in favor of acute generalized polyradiculoneuropathy. Laboratory evaluation revealed hypoglycorrhachia. She treated with plasmapheresis after two weeks; she was discharged from hospital, but neurological recovery was not complete. After 6 months, she came back with acute onset of weakness in lower limbs, back pain, fever and urinary incontinence. Pinprick and light touch complete sensory loss was found beneath umbilicus. Thoracic MRI with contrast revealed a dorsal epidural mass extending smoothly from T8 to T12 (10 cm) with spinal cord compression. She underwent urgent laminectomy for spinal cord decompression. Histological examination revealed small round cell tumor suggestive of malignant T-cell type lymphoma. In cases with Guillain-Barré syndrome presentation, systemic hematologic disorders such as non-Hodgkin's lymphoma should be considered as one of the differential diagnosis of underlying disease.


Assuntos
Síndrome de Guillain-Barré/etiologia , Linfoma não Hodgkin/complicações , Descompressão Cirúrgica/métodos , Diagnóstico Diferencial , Feminino , Síndrome de Guillain-Barré/diagnóstico , Humanos , Laminectomia , Linfoma não Hodgkin/diagnóstico , Imageamento por Ressonância Magnética , Compressão da Medula Espinal/diagnóstico por imagem , Compressão da Medula Espinal/etiologia , Compressão da Medula Espinal/cirurgia , Tomografia Computadorizada por Raios X , Adulto Jovem
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