[Comparative studies of the effects of fly ash, soil dust and clay on selected structures of the visual system of female albino rats]. / Badania porównawcze nad wplywem popiolów lotnych, pylów glebowych i glin na wybrane struktury ukladu wzrokowego szczurzyc bialych.

Observations were carried out on 65 white she-rats. The animals received by+intraconjunctival+route a suspension of volatile ashes from ventilators of electricity works, a suspension of the soil from the area of the power-houses and a suspension of clay from clay mines. The animals exhibited marginal blepharitis and conjunctivitis appearing in the 3-5 days of investigation. The observations point to pollution of the soil of the power-house area and to the noxiousness of the investigated dusts which should be classified to the category of burdensome dusts.

[Histological studies and clinical observations of the effect of various types of dust on the organ of vision of small laboratory animals]. / Bodania histologiczne i obserwacje kliniczne wplywu róznych pylów na narzad wzroku malych zwierzat laboratoryjnych.

For seven days, three times a day, female rats were instilled into their conjunctival sacs suspensions of power plant dusts, soil and clay. Clinically observed were inflammatory changes of the conjunctiva and cyclids margins as well as traumatisation of the corneal and conjunctival epithelia, appearing at different stages on the experiment. Cytoenzymatic examinations indicated disturbances of oxidation and reduction processes, changes in dialysis through physiologic membranes and dissociation of protein synthesis.

[Determining acid phosphatase (AcP[E.C. 3.1.3.2.]) and adenosine triphosphatase (ATPase [E.C. 3.6.1.3.]) activity in the lungs of rats following a single administration of ashes from industrial high-heat facilities]. / Aktivitätsbeurteilung von saurer Phosphatase (AcP[E.C. 3.1.3.2.]) und Adenosintriphosphatase (ATP-ase [E.C. 3.6.1.3.]) in Lungen von Ratten nach einmaliger Applikation von Aschen aus Kraftwerk-Grossfeueranlagen.

There was examined pulmonary tissue of white rats, which had been administered intratrachealy a single dose of the respirable fraction of ashes sample from 6 different power stations elektrohasting plants and hasting plants in Poland (0.2 ml suspension; 50 mg of the examined sample in 0.6 cm3 of NaCl solution). 9 months after the application of the ashes, biopsies of the left lung were taken and there was determined the activity of acid phosphatase (AcP) and adenosinetriphosphatase (ATP-ase) histoenzymatically. There was found sensitivity of these hydrolases and changes of their activity connected with chemical composition of the examined ashes.

[Effect of short-term exposure to ash from electric power plants on histochemical reactions of succinate dehydrogenase and lactate dehydrogenase in the lungs of experimental animals]. / Wplyw krótkotrwalego dzialania popiolów elektroenergetycznych na odczyny histochemiczne dehydrogenazy bursztynianowej (SDH) E.C.1.3.99.1 i dehydrogenazy mleczanowej (LDH) E.C.1.1.1.27 w plucach zwierzat doswiadczalnych.

Histochemical studies of the activity of succinic dehydrogenase (SDH) and lactic dehydrogenase (LDH) in the pulmonary tissue of experimental animals which were given four coal ashes issued from different thermal-electric power stations: group VII--from the thermal-electric power station Siekierki (Warsaw), group VIII--from Wroclaw, group IX--from Leg (Cracow) and group XI--from Lódz, were carried out. In particular ash samples the content of trace elements and free silica was determined. The studies yield the following conclusions: 1. The activity of succinic dehydrogenase (SDH) and lactic dehydrogenase (LDH) was changed in the respiratory tract and pulmonary alveoli as a result of the electroenergetic ashes applied. 2. Changes in cytoenzymatic reactions of SDH and LDH vary with the type of ash applied. The greatest changes were found in group XI where the ashes contained almost doubled amount of such elements as Mn, Zn, Pb, Cu. 3. SDH exhibited a greater sensitivity to the effects of electroenergetic ashes, as compared to LDH. 4. Changes in the activity of the test SDH and LDH enzymes indicate disorders in oxydoreductory processes of cells.

[Effect of biseptol on the adrenal cortex of the white rat in postoperative shock]. / Der Einfluss von Biseptol auf die Nebennierenrinde der weissen Ratte im postoperativen Schock.

The study aimed to find out the effect of sulfonamide combined with Trimetaprim-Biseptol 480 on the adrenal cortex in post-operative shock after removal of SPIGELian lobe (lobectomy of the lobus caudatus and unilaterally of one kidney with its suprarenal gland. The study was performed on a material of white rats which were post-operatively administered Biseptol 480 in doses 5 times bigger than those given to men. It was attempted to determine histochemically the intensity of the adrenal cortex' function by testing the number of lipid droplets, activity of the main enzyme of steroidogenesis (beta-hydroxy steroid dehydrogenase) and the level of alpha-ketols (as the final stage of steroidogenesis). Pathomorphologic examinations were also performe. On the basis of the present study's results, it was observed that - in the case of liver-lobectomy - the zona fasciculata and zona reticularis are functionally stimulated but the zona glomerulosa becomes insufficient. In the case of nephrectomy plus suprarenal gland's removal, all the adrenal cortex becomes insufficient. Administration of Biseptol in the 1st case contributed to hormonal inactivation of the zone glomerulosa cells, but in the 2nd case, it caused an increased activity of steroid dehydrogenase and an increase of the alpha-ketol level in the zona fasciculata.