Stefan Jellinek (1871-1968): The only professor of electro-pathology.

The exploding use of electricity in homes and industry in the second half of the 19th century was accompanied by many injuries and fatalities from electric currents. Their study by my father was the serendipitous outcome of his early work on possible blood pressure changes from electric currents in a career that started in internal medicine. It became his limited field of electro-pathology which embraced first aid, the care of the injured, histopathology and accident prevention. He was an enthusiastic teacher and collector of specimens, from tree trunks struck by lightning down to the microscopy of accidental and experimental electric lesions.

Sarcophilia, cremation and Sir Henry Thompson (1820-1904).

Sarcophilia, a neologism for an attachment to human remains, is set in a review of the history of the disposal of the dead. The ancient practice of cremation was relaunched late in the 19th century by the urological surgeon cum social reformer Sir Henry Thompson. He was stimulated by Edwin Chadwick and Charles Dickens, and by Charles Darwin's observations on the earthworm. Sarcophilia is the reason for the controversial Human Tissue Act of 2004.

Medical advertising: the Family Encyclopaedia of Medicine scandal of 1914.

The past 100 years have seen a transition from a total ban in Britain on all advertising by doctors to the laity to almost total freedom of medical information, with probable benefit to public health but also a risk of loss of privacy. The Family Encyclopaedia of Medicine, written by Dr Hugh Howard Riddle and published by Lord Northcliffe's Daily Mail in 1914, started a flood of medical journalism in the press and the newer media. The lavishly advertised misattribution of its authorship to 'thirty eminent specialists', including Clifford Allbutt and William Osler, caused a major rumpus in the London Royal College of Physicians, but the fortnightly publication continued and became a four-volume book, popular with a public avid for more and more medical information.

Before the welfare state: Bastian's Civil List pension.

Bastian, an eminent, if controversial, naturalist, pioneer neurologist, and for 30 years, professor at University College, London, ended with a certain income of only L75 in his last year. Sir James Crichton-Browne initiated the grant of a Civil List pension. Prime Minister H Asquith, after consulting the London Royal Society, advised King George V to disburse a pension of L150.

Dr H C Bastian, scientific Jekyll and Hyde.

The neurological library of S A Kinnier Wilson, now in the Royal College of Physicians of Edinburgh, contains two books by Henry Charlton Bastian. Various forms of hysterical or functional paralysis (1893) is inscribed "To Dr Wilson by the Author, July 1906". Wilson was Bastian's house-physician at the time. The second book, given to Wilson's son by Bastian's daughter in 1940, is a lavishly illustrated tome, Studies in heterogenesis (1903). The two books testify to a scientific Jekyll and Hyde--one of the founders of neurology and a wildly unorthodox biologist.

Major neurological disease and occupational exposure to organic solvents.

Five patients are described who presented with major organic brain disease affecting one or more of pyramidal and extrapyramidal tracts, cerebellum, and higher cortical functions. All had a history of 10 years or more of regular occupational exposure to solvents in confined spaces, three in painting inside ships and the others in weapons maintenance and printing. All had been regularly exposed to high air vapour peaks as well as to skin contamination. Four showed some evidence of improvement after the exposure ceased. None was initially suspected of having a toxic encephalopathy by the consultant to whom he was referred. The spectrum of neurological disease presented by these men mirrors closely that described in solvent abusers. All were forced by illness to retire from their work, a circumstance which might have in the past have led to such conditions being missed in cross-sectional studies, which in general have not shown evidence of major disease. We suggest that when such disease occurs nowadays, its cause is usually not suspected. Further epidemiological study of the problem is necessary.