1.
Toxicol Mech Methods
; 18(6): 469-471, 2008 Jul.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19696942
RESUMO
beta-Carotene ethenolysis under promotion of well-defined ruthenium catalysts were examined as a novel method of synthesis of vitamin A derivatives. Efficient reaction was promoted by the second-generation Hoveyda catalyst. The products of ethenolysis in positions C15-C15', C11-C12, and C9-C10 were detected, but cleavage of the C11-C12 double bond predominated. Even better regioselectivity at this position was observed for cross-metathesis between beta-carotene and functionalized alkenes.