1.
Mol Divers
; 3(2): 113-6, 1997.
Artigo
em Inglês
| MEDLINE
| ID: mdl-9593180
RESUMO
A library of potential agonists and antagonists for adrenergic receptors was prepared using high-throughput solution-phase parallel synthesis. Traditional solution-phase reductive amination reactions followed by rapid purification by ion exchange chromatography yielded products with near-analytical purity. An array of ketones and amines, arranged in an 8 x 12 matrix, were combined to form 96 individual compounds.