Incremental significance and sex discrepancies of neck circumference on the odds of ischaemic stroke: a multistage, population-based, cross-sectional study from Northeast China.

OBJECTIVES: Accumulated evidence suggests that neck circumference (NC) is associated with cardiometabolic risk factors. However, limited studies are available regarding the association between NC or height normalised NC (neck-to-height ratio (NHR)) and risk of ischaemic stroke (IS) in the Chinese population. Therefore, we aimed at examining the associations between NC or NHR and odds of IS and exploring the discrepancies between men and women. DESIGN: A multistage cluster cross-sectional study. SETTING: A population-based study carried out in Northeast China. METHODS: A cross-sectional study was undertaken in Northeast China between September 2017 and March 2019, involving 7236 men and 11 352 women, respectively. The median age of participants was 60.30 years, ranging from 40 to 97 years. The associations between NC or NHR and odds of IS were calculated using multiple logistic regression models. Dose-response relationships were depicted using restricted cubic spline functions. Reclassification analyses were carried out to determine the incremental significance of NC or NHR on the odds of IS. RESULTS: In women, NC and NHR were significantly associated with the odds of IS, independent of traditional risk factors and other anthropometric parameters for obesity. The highest quartile of NC and NHR had a 1.60 (95% CI 1.16 to 2.22)-and 1.72 (95% CI 1.23 to 2.41) times higher odds of IS compared with the lowest quartile. Furthermore, the odds of IS increased by 1.10 (95% CI 1.01 to 1.20) and 1.12 (95% CI 1.02 to 1.22) times per 1 SD increase in NC and NHR, respectively. Reclassification analyses showed that the proportion of correct classification increased by 11.5% (95% CI 2.2% to 20.7%) and 22.8% (95% CI 13.5% to 32.0%) after the addition of NC or NHR into established models, respectively. However, the findings could not be replicated in men. CONCLUSION: NC and NHR might be promising independent indicators for women IS. Their incremental value in the risk stratification of IS enables the individualised prevention of IS in women.

Analysis of Influencing Factors for Chronic Diseases: A Large Sample Epidemiological Survey from Liaoyang.

Purpose: Northeast China is a region with a serious aging population. There are fewer articles on epidemiological surveys on the prevalence of chronic diseases in aging areas of China. The study is aimed at understanding the prevalence of chronic noncommunicable diseases such as hypertension and diabetes mellitus (DM) in Liaoning Province, northeast China, and analyzing the risk factors for these chronic diseases. Methods: A questionnaire survey and physical examination were conducted in 5008 permanent residents in 2 streets (Henan Street and Hebei Street) covered by Liuerbao Central Health Center in Liaoyang and 4 villages (Miaogou Village, Wangjia Village, Heyan Village, and Shuiquan Village) covered by Shuiquan Health Center in Tianshui Town of Liaoyang from January 2020 to December 2020. Results: A total of 4990 patients were included. The prevalence rates of hypertension, DM, dyslipidemia, and obesity in residents in Liaoyang were 54.13%, 12.30%, 43.31%, and 20.52%, respectively. The prevalence of hypertension and DM was highest in both male and female patients aged 40-60 years, which was higher than that in the other age groups (P < 0.05). The prevalence of dyslipidemia was highest in men over 60 years old and women 18 - <40 years old. Obesity was most common in men aged over 60 and in women 40 - <60 years old. The proportion of male smokers in all age groups was significantly higher than that of female smokers. Smoking, dyslipidemia, and significant overweight or obesity are common risk factors for hypertension and DM. Conclusion: In Liaoyang, northeast China, the prevalence of noninfectious chronic diseases was high, and the prevalence rate in people over 40 years old was significantly higher than that in people under 40 years old. The prevalence and progression of chronic diseases were obviously related to local living and eating habits; thus, health education needs to be improved.

Epidemiology of stroke in urban northeast China: A population-based study 2018-2019.

BACKGROUND: Stroke has been emerging as the major public health challenge in China. In the present study, we sought to comprehensively estimate of stroke burden in urban northeast China. METHODS: We conducted the cross-sectional study in 5424 adults aged ≥ 40 years (response rate was 85.3%) living in urban northeast China. A multi-stage cluster sampling method was employed to ensure the population was representative. The prevalent stroke patients were defined as survivors on 31 March 2018. Stroke was defined based on the WHO criteria and was classified into ischemic stroke (IS) and hemorrhage stroke (HS) according to the imaging results. RESULTS: A total of 292 stroke cases were confirmed (IS-260, 35-HS, and IS concomitant HS-3). Crude prevalence of overall stroke, IS and HS were 5.4%, 4.8% and 0.6%, respectively, and the age-standardized prevalence was 3.8%, 3.4% and 0.5%, respectively. The prevalence of stroke was significantly higher in men compared to women. Among stroke population, 4.5% had disabilities and lived with consequences of stroke. Hypertension, dyslipidemia and diabetes were highly prevalent, accounting for 80.5%, 59.7% and 39.3%, respectively, in stroke population. However, the control rates of those comorbidities were unacceptably low (13.2%, 8.1% and 40.4%, respectively). CONCLUSION: The considerable stroke burden was observed in urban northeast China with high proportion of stroke and related risk factors. Poorly controlled comorbidities are likely to contribute to the substantial burden in the future. Long-term primary and secondary prevention should be highlighted in urban northeast China.