[A population genetic study of 22 autosomal loci of single nucleotide polymorphisms].

OBJECTIVE: To evaluate polymorphisms and forensic efficiency of 22 non-binary single nucleotide polymorphism (SNP) loci. METHODS: One hundred ethnic Han Chinese individuals were recruited from Dongguan, Guangdong. The 22 loci were genotyped with matrix-assisted laser desorption/ionization time of flight mass spectrometry (MALDI-TOF MS). RESULTS: Nine loci were found with a single allele, 4 loci were found to be biallelic, whilst 9 loci were found to have 3 alleles. For 13 polymorphic loci, the combined discrimination power and power of exclusion were 0.999 98 and 0.9330, respectively. For the 9 non-biallelic loci, the combined discrimination power and power of exclusion were 0.9998 and 0.8956, respectively. For motherless cases, the combined power of exclusion was 0.6405 for 13 polymorphic SNPs and 0.6405 for 9 non-binary SNPs. CONCLUSION: Non-binary loci have a greater discrimination power and exclusion power per SNP.

Assessing forensic applications of the frontal sinus in a Chinese Han population.

The frontal sinus is an important tool of personal identification. To assess the forensic applications of the frontal sinus patterns in a Chinese Han population, 198 individuals were analyzed. 165 individuals who have the frontal sinus were observed in this population, and 12 parameters of the frontal sinus were observed according to Yoshino's method. The same combined code was found in three persons from our samples. The unilateral frontal sinus scalloped with one arcade has few parameters applied to personal identification, and shows the poorer discrimination power. These parameters showed better discrimination power in our population, and could be applied to personal identification.