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2.
Zhonghua Shao Shang Za Zhi ; 34(10): 731-735, 2018 Oct 20.
Artigo em Chinês | MEDLINE | ID: mdl-30369144

RESUMO

Objective: To explore the difference between the nursing needs of burn patients and nurses' cognition in order to adjust the nursing service behavior and improve the nursing quality. Methods: The convenience sampling method was adopted to select 400 burn inpatients admitted to the Department of Burns of the 180th Hospital of the People's Liberation Army from January to September 2017, and 38 nurses from the same department were selected by cluster sampling method. On the day of or the day before hospital discharge after instruction to discharging patients, the self-designed questionnaire was adopted to investigate the nursing needs of patients during hospitalization. The cognitive differences between patients and nurses in the overall level and specific dimensions of nursing needs were compared, and items of the nursing needs of patients which were higher than the cognition of nurses with statistically significant differences were recorded. The five most important nursing needs items considered by both patients and nurses were recorded and compared. Data were processed with independent sample t test. Results: The effective recovery rates of questionnaire for patients and nurses were 94.8% (379/400) and 100.0% (38/38), respectively. The total score of patients' nursing needs was (3.9±0.4) points, which was similar to (4.1±0.5) points of nurses' cognition of patients' nursing needs (t=1.611, P>0.05). The scores of patients' physiological needs and self-esteem needs dimensions were (4.0±0.6) and (3.9±0.6) points, respectively, significantly lower than (4.2±0.4) and (4.3±0.5) points of nurses (t=-2.476, -4.160, P<0.05 or P<0.01). The scores of patients' safety needs, love and belonging needs, and self-realization needs dimensions were similar to those of nurses (t=0.228, 1.356, -1.010, P>0.05). The scores of the patients in nursing needs items of the introduction of patients in the same room, medical staff accompanying them during the examination, leisure and recreational activities, the theoretical and technical proficiency of nurses, the guidance of anti-scar exercise, and the propaganda of drug knowledge were respectively (4.2±0.9), (3.3±1.2), (4.2±0.9), (4.5±0.7), (4.2±0.9), and (4.0±1.0) points, significantly higher than (3.5±0.9), (2.7±1.0), (3.5±1.3), (4.1±0.8), (3.8±1.0), and (3.6±0.9) points of the nurses (t=4.147, 3.515, 3.374, 3.282, 2.546, 2.265, P<0.05 or P<0.01). The five most important items for patients and nurses were pain nursing, the theoretical and technical proficiency of nurses, treating patients equally, instruction to discharging patients, timely visiting wards and privacy protection, pain nursing, introduction of medical staff, introduction of safety issues, getting the daily expenses listing, respectively. Only pain nursing was the same between patients and nurses. Conclusions: There are some differences between burn patients and nurses in the dimensions and items of nursing needs and the most important items of nursing needs. Nursing staff should focus on improving the nursing service items with insufficient cognition, adjusting the service supply, meeting the reasonable needs of patients, and improving the nursing satisfaction of patients.


Assuntos
Queimaduras/enfermagem , Cognição/fisiologia , Pacientes Internados , Adulto , Hospitalização , Humanos , Enfermeiras e Enfermeiros , Inquéritos e Questionários
3.
Genet Mol Res ; 16(1)2017 Feb 08.
Artigo em Inglês | MEDLINE | ID: mdl-28198500

RESUMO

Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a crucial adaptor molecule of the interleukin-1 receptor/Toll-like receptor (IL-1/TLR) superfamily, which can trigger downstream signaling cascades involved in innate immunity. The function of TRAF6 has been clarified in mammals but is poorly understood in chicken. In our study, we investigated TRAF6 function in birds, particularly in chicken innate immune responses, by cloning and characterizing chicken TRAF6 (chTRAF6). The full-length coding sequence of chTRAF6 comprised 1638 bp and encoded a 545-amino acid protein, which shares high sequence similarity with TRAF6 of other species and consists of four structurally conserved domains. Quantitative real-time polymerase chain reaction revealed that chTRAF6 was widely expressed in all tested tissues and its expression was induced in chicken embryo fibroblast cells treated with poly(I:C) and poly(dA:dT). Increased expression of chTRAF6 was observed both in vitro and in vivo following infection with Newcastle disease virus in chickens. Taken together, these results suggest that chTRAF6 plays a vital role in host defense against viral infection in chicken.


Assuntos
Proteínas Aviárias/genética , Galinhas/genética , Fator 6 Associado a Receptor de TNF/genética , Animais , Proteínas Aviárias/química , Proteínas Aviárias/metabolismo , Galinhas/imunologia , Galinhas/metabolismo , Resistência à Doença/genética , Resistência à Doença/imunologia , Expressão Gênica , Imunidade Inata/genética , Domínios e Motivos de Interação entre Proteínas , Transdução de Sinais , Fator 6 Associado a Receptor de TNF/química , Fator 6 Associado a Receptor de TNF/metabolismo
4.
Rev Sci Instrum ; 85(9): 095114, 2014 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-25273779

RESUMO

We describe a system to transport and identify barium ions produced in liquid xenon, as part of R&D towards the second phase of a double beta decay experiment, nEXO. The goal is to identify the Ba ion resulting from an extremely rare nuclear decay of the isotope (136)Xe, hence providing a confirmation of the occurrence of the decay. This is achieved through Resonance Ionization Spectroscopy (RIS). In the test setup described here, Ba ions can be produced in liquid xenon or vacuum and collected on a clean substrate. This substrate is then removed to an analysis chamber under vacuum, where laser-induced thermal desorption and RIS are used with time-of-flight mass spectroscopy for positive identification of the barium decay product.

5.
Cancer Radiother ; 17(4): 297-303, 2013.
Artigo em Inglês | MEDLINE | ID: mdl-23849438

RESUMO

PURPOSE: To investigate the prognosis of three subgroups of locoregionally advanced nasopharyngeal carcinoma treated with intensity-modulated radiotherapy and platinum-based chemotherapy. PATIENTS AND METHODS: Hundred and eighty-one consecutive patients with locoregionally advanced untreated nasopharyngeal carcinoma were retrospectively divided into three subgroups: locally advanced group (T3-4N0-1M0), regionally advanced group (T1-2N2-3M0) and the mixed group (T3-4N2-3M0). They were all treated with definitive intensity-modulated radiotherapy and platinum-based chemotherapy. Their prognosis were investigated and compared. Multivariate analysis was applied to identify the independent risk factors of study endpoints. RESULTS: The 3-year locoregional control rates for locally advanced group, regionally advanced group, and the mixed group were 91.5%, 90.6% and 84.3% respectively, no significant difference was observed (P=0.656, P=0.429). The 3-year distant metastasis-free survival rates were 89.6%, 75.7% and 76.3%, respectively. The distant metastasis-free survival rate of the locally advanced group was significantly higher than the other two subgroups (P=0.028, P=0.028). The 3-year progression-free survival rates were 85.5%, 67.9% and 67.1% respectively with significance also favoring the locally advanced group (P=0.043, P=0.023). Nodal stage and the performance status were the independent risk factors of distant metastasis in the observed period. CONCLUSIONS: In the context of intensity-modulated radiotherapy and platinum-based chemotherapy, the locally advanced group had a better prognosis compared with the regionally advanced group and the mixed group. Treatment stratification may be based on nodal stage.


Assuntos
Protocolos de Quimioterapia Combinada Antineoplásica/uso terapêutico , Carcinoma/radioterapia , Quimioterapia Adjuvante , Neoplasias Nasofaríngeas/radioterapia , Terapia Neoadjuvante , Radioterapia de Intensidade Modulada , Adulto , Protocolos de Quimioterapia Combinada Antineoplásica/administração & dosagem , Carcinoma/tratamento farmacológico , Carcinoma/patologia , Carcinoma/secundário , Terapia Combinada , Intervalo Livre de Doença , Feminino , Fluoruracila/administração & dosagem , Seguimentos , Humanos , Estimativa de Kaplan-Meier , Metástase Linfática , Masculino , Pessoa de Meia-Idade , Neoplasias Nasofaríngeas/tratamento farmacológico , Neoplasias Nasofaríngeas/patologia , Estadiamento de Neoplasias , Compostos Organoplatínicos/administração & dosagem , Paclitaxel/administração & dosagem , Transfusão de Plaquetas , Prognóstico , Estudos Retrospectivos , Fatores de Risco , Resultado do Tratamento
6.
Br J Radiol ; 85(1016): e388-94, 2012 Aug.
Artigo em Inglês | MEDLINE | ID: mdl-22374285

RESUMO

OBJECTIVES: To evaluate the effects of heart rate and heart rate variability on image quality, patient dose and diagnostic accuracy of 320-detector row CT. METHODS: 94 patients were prospectively enrolled. Heart rate was defined as the mean value of different intervals elapsing between two consecutive R waves in an electrocardiogram (R-R intervals) and the heart rate variability was calculated as the standard deviation from the average heart rate. The image quality was evaluated by four grades, according to motion artefacts ("step artefacts" and "blurring artefacts"). The diagnostic accuracy was analysed in 43 patients who were scheduled for invasive coronary angiography (ICA). The coeffects of heart rate and heart rate variability on image quality, radiation dose and diagnostic accuracy were evaluated by multivariate regression. RESULTS: The mean image quality score was 1.2 ± 0.5 and the mean effective dose was 14.8 ± 9.8 mSv. The results showed that heart rate (74.0 ± 11.2 beats per minute) was the single factor influencing image quality (p<0.001) and radiation dose (p<0.001), while heart rate variability (3.7 ± 4.6) had no significant effect on them (p=0.16 and p=0.47, respectively). For 43 patients who underwent ICA, heart rate and heart rate variability showed no influence on the accuracy (p=0.17 and p=0.12, respectively). Overall sensitivity was 97.4% (37/38), specificity was 99.4% (351/353), positive predictive value was 94.9% (37/39) and negative predictive value was 99.7% (351/352). CONCLUSION: 320-detector row CT, with improved longitudinal coverage of detector, resolves step artefact and high patient dose caused by irregular heart rate. However, it is still recommended to control heart rate to a lower level to eliminate blurring artefact and radiation dose.


Assuntos
Angiografia Coronária/métodos , Doença da Artéria Coronariana/diagnóstico por imagem , Frequência Cardíaca , Tomografia Computadorizada Multidetectores/métodos , Idoso , Artefatos , Angiografia Coronária/normas , Relação Dose-Resposta à Radiação , Eletrocardiografia , Feminino , Humanos , Masculino , Pessoa de Meia-Idade , Tomografia Computadorizada Multidetectores/normas , Estudos Prospectivos , Doses de Radiação , Sensibilidade e Especificidade
7.
Transplant Proc ; 41(5): 1499-503, 2009 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-19545665

RESUMO

BACKGROUND: Ischemia-reperfusion (I/R) injury had been linked to primary graft dysfunction in transplantation. To find effective methods to alleviate donor liver injury from I/R, we transferred exogenous human telomerase reverse transcriptase (hTERT) genes into donor rats before liver transplantation. METHODS: SD rats (age, 16 months) were divided into 3 groups: group A were donors pretreated with exogenous hTERT gene; group B were donors pretreated with adenovirus vector only; and group C were donors pretreated with physiologic saline. Alanine aminotransferase (ALT), apoptotic index, telomerase activity, and histological evaluation were calculated after liver transplantation. RESULTS: The levels of ALT and apoptotic index of group A were significantly lower than those of group B or group C (P < .05), at the same time, a mild histological injury and increased telomerase activity were also observed in group A. CONCLUSIONS: Exogenous hTERT gene provides protection against I/R injury, which depends on exogenous hTERT gene-mediated inhibition of apoptosis.


Assuntos
Transplante de Fígado/fisiologia , Fígado/patologia , Traumatismo por Reperfusão/prevenção & controle , Telomerase/genética , Doadores de Tecidos , Adenoviridae/genética , Animais , Apoptose/fisiologia , Técnicas de Transferência de Genes , Engenharia Genética/métodos , Sobrevivência de Enxerto , Humanos , Masculino , Ratos , Ratos Sprague-Dawley , Telomerase/metabolismo
8.
Phys Rev Lett ; 101(10): 102004, 2008 Sep 05.
Artigo em Inglês | MEDLINE | ID: mdl-18851209

RESUMO

We observe an obvious anomalous line shape of the e;{+}e;{-}--> hadrons total cross sections in the energy region between 3.700 and 3.872 GeV. It is inconsistent with the explanation for only one simple psi(3770) resonance with a statistical significance of 7sigma. The anomalous line shape may be explained by two possible enhancements of the inclusive hadron production near the center-of-mass energies of 3.764 and 3.779 GeV, indicating that either there is likely a new structure in addition to the psi(3770) resonance around 3.773 GeV, or there are some physics effects reflecting the DD[over ] production dynamics.

9.
Phys Rev Lett ; 100(19): 192001, 2008 May 16.
Artigo em Inglês | MEDLINE | ID: mdl-18518438

RESUMO

Using psi(2S) --> pi(+)pi(-) J/psi events in a sample of 14.0 x 10(6) psi(2S) decays collected with the BES-II detector, a search for the decay of the J/psi to invisible final states is performed. No signal is found, and an upper limit at the 90% confidence level is determined to be 1.2 x 10(-2) for the ratio B(J/psi --> invisible)/B(J/psi-->mu(+)mu(-)). This is the first search for J/psi decays to invisible final states.

10.
Phys Rev Lett ; 100(10): 102003, 2008 Mar 14.
Artigo em Inglês | MEDLINE | ID: mdl-18352176

RESUMO

The decays of J/psi --> etaphif(0)(980)[eta --> gammagamma, phi --> K(+) K(-), f(0)(980) --> pi(+)pi(-)] are analyzed using a sample of 5.8 x 10(7) J/psi events collected with the BESII detector at the Beijing Electron-Positron Collider. A structure at around 2.18 GeV/c(2) with about 5 sigma significance is observed in the phif(0)(980) invariant mass spectrum. A fit with a Breit-Wigner function gives the peak mass and width of m = 2.186+/-0.010(stat)+/-0.006(syst) GeV/c(2) and Gamma = 0.065+/-0.023(stat)+/-0.017(syst) GeV/c(2), respectively, which are consistent with those of Y(2175), observed by the BABAR Collaboration in the initial-state radiation process e(+)e(-) --> gamma(ISR) phif(0)(980). The production branching ratio is determined to be Br(J/psi --> etaY(2175))Br(Y(2175)- -> phif(0)(980))Br(f(0)(980) --> pi(+)pi(-)) = [3.23+/-0.75(stat)+/-0.73(syst)] x 10(-4), assuming that the Y(2175) is a 1(--) state.

11.
Phys Rev Lett ; 99(1): 011802, 2007 Jul 06.
Artigo em Inglês | MEDLINE | ID: mdl-17678148

RESUMO

Using 14 x 10(6) psi(2S) events accumulated at the BESII detector, we report first measurements of branching fractions or upper limits for psi(2S) decays into gammapp, gamma2(pi+pi-), gammaKS0K+pi-+c.c., gammaK+K-pi+pi-, gammaK*0K-pi++c.c., gammaK*0K*0, gammapi+pi-pp, gamma2(K+K-), gamma3(pi+pi-), and gamma2(pi+pi-)K+K- with the invariant mass of hadrons below 2.9 GeV/c2. We also report branching fractions of psi(2S) decays into 2(pi+pi-)pi0, omegapi+pi-, omegaf2(1270), b1+/-pi-/+, and pi02(pi+pi-)K+K-.

12.
Phys Rev Lett ; 97(14): 142002, 2006 Oct 06.
Artigo em Inglês | MEDLINE | ID: mdl-17155241

RESUMO

A broad peak is observed at low K+K- invariant mass in J/psi-->K+K-pi(0) decays found in a sample of 5.8x10(7) J/psi events collected with the BESII detector. The statistical significance of the broad resonance is much larger than 5sigma. A partial wave analysis shows that the J;{PC} of this structure is 1--. Its pole position is determined to be [1576(-55)(+49)(stat)-91+98(syst)] MeV/c(2)-i/2[818(-23)(+22)(stat)-133+64(syst)] MeV/c(2). These parameters are not compatible with any known meson resonances.

13.
Phys Rev Lett ; 97(20): 202002, 2006 Nov 17.
Artigo em Inglês | MEDLINE | ID: mdl-17155676

RESUMO

Using a data sample of 58 x 10(6) J/psi decays collected with the Beijing Spectrometer II detector at the Beijing Electron Positron Collider, searches for invisible decays of eta and eta' in J/psi to phi eta and phi eta' are performed. The phi signals, which are reconstructed in K+K- final states, are used to tag the eta and eta' decays. No signals are found for the invisible decays of either eta or eta', and upper limits at the 90% confidence level are determined to be 1.65 x 10(-3) for the ratio B(eta-->invisible)/B(eta --> gamma gamma) and 6.69 x 10(-2) for B(eta' --> invisible)/B(eta' --> gammagamma). These are the first searches for eta and eta' decays into invisible final states.

14.
Phys Rev Lett ; 97(12): 121801, 2006 Sep 22.
Artigo em Inglês | MEDLINE | ID: mdl-17025950

RESUMO

We measure the branching fractions for psi(3770)-->D(0)D[over ](0), D+D-, DD[over ], and non-DD[over ] to be (46.7+/-4.7+/-2.3)%, (36.9+/-3.7+/-2.8)%, (83.6+/-7.3+/-4.2)%, and (16.4+/-7.3+/-4.2)%, respectively. The resonance parameters of psi(3770) and psi(2S) are measured to be M_(psi(3770))=3772.2+/-0.7+/-0.3 MeV, Gamma_(psi(3770))(tot)=26.9+/-2.4+/-0.3 MeV, and Gamma_(psi(3770))(ee)=251+/-26+/-11 eV; M_(psi(2S))=3685.5+/-0.0+/-0.3 MeV, Gamma_(psi(2S))(tot)=331+/-58+/-2 keV, and Gamma_(psi(2S))(ee)=2.330+/-0.036+/-0.110 keV. We also measure the light hadron R value to be R(uds)=2.262+/-0.054+/-0.109 in the energy region from 3.660 to 3.872 GeV.

15.
Phys Rev Lett ; 97(6): 062001, 2006 Aug 11.
Artigo em Inglês | MEDLINE | ID: mdl-17026161

RESUMO

The decay J/psi-->NNpi provides an effective isospin 1/2 filter for the piN system due to isospin conservation. Using 58x10(6) J/psi decays collected with the Beijing Electromagnetic Spectrometer at the Beijing Electron Positron Collider, more than 100 thousand J/psi-->ppi-n+c.c. events are obtained. Besides the two well-known N* peaks at around 1500 MeV/c2 and 1670 MeV/c2, there are two new, clear N* peaks in the ppi invariant mass spectrum around 1360 MeV/c2 and 2030 MeV/c2 with statistical significance of 11sigma and 13sigma, respectively. We identify these as the first direct observation of the N*(1440) peak and a long-sought missing N* peak above 2 GeV/c2 in the piN invariant mass spectrum.

16.
Phys Rev Lett ; 96(16): 162002, 2006 Apr 28.
Artigo em Inglês | MEDLINE | ID: mdl-16712215

RESUMO

An enhancement near threshold is observed in the omega(phi) invariant mass spectrum from the doubly Okubo-Zweig-Iizuka-suppressed decays of J/psi-->gamma(omega)phi, based on a sample of 5.8 x 10(7) J/psi events collected with the BESII detector. A partial wave analysis shows that this enhancement favors JP=0+, and its mass and width are M=1812(+19)(-26)(stat)+/-18(syst) MeV/c2 and Gamma=105+/-20(stat)+/-28(syst) MeV/c2. The product branching fraction is determined to be B(J/psi-->gammaX)B(X-->omega(phi))=[2.61+/-0.27(stat)+/-0.65(syst)]x10(-4).

17.
Phys Rev Lett ; 97(26): 262001, 2006 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-17280420

RESUMO

We report measurements of the continuum R(uds) near the center-of-mass energy of 3.70 GeV, the R[uds(c)+psi(3770)](s) and the R(had)(s) values in e(+)e(-) annihilation at 68 energy points in the energy region between 3.650 and 3.872 GeV with the BES-II detector at the BEPC Collider. We obtain the R(uds) for the continuum light hadron (containing u, d, and s quarks) production near the DD threshold to be R(uds)=2.141+/-0.025+/-0.085.

18.
Phys Rev Lett ; 95(26): 262001, 2005 Dec 31.
Artigo em Inglês | MEDLINE | ID: mdl-16486345

RESUMO

The decay channel J/psi --> gamma(pi)(+)pi(-)eta is analyzed using a sample of 5.8 x 10(7) J/psi events collected with the BESII detector. A resonance, the Chi(1835), is observed in the pi(+)pi(-)eta invariant-mass spectrum with a statistical significance of 7.7 sigma. A fit with a Breit-Wigner function yields a mass M = 1833.7 +/- 6.1(stat) +/- 2.7(syst) MeV/c(2), a width Tau = 67.7 +/- 20.3(stat) +/- 7.7(syst) MeV/c(2), and a product branching fraction B(J/psi --> gammaChi) . B(Chi --> pi(+)pi(-)eta) = [2.2 +/- 0.4(stat) +/- 0.4(syst)] x 10(-4). The mass and width of the Chi(1835) are not compatible with any known meson resonance. Its properties are consistent with expectations for the state that produces the strong pp mass threshold enhancement observed in the J/psi --> gammapp process at BESII.

19.
Phys Rev Lett ; 93(11): 112002, 2004 Sep 10.
Artigo em Inglês | MEDLINE | ID: mdl-15447331

RESUMO

An enhancement near the m(p)+M(Lambda) mass threshold is observed in the combined pLambda and pLambda invariant-mass spectrum from J/psi-->pK(-)Lambda;+c.c. decays. It can be fit with an S-wave Breit-Wigner resonance with a mass m=2075+/-12(stat)+/-5(syst) MeV and a width of Gamma=90+/-35(stat)+/-9(syst) MeV; it can also be fit with a P-wave Breit-Wigner resonance. Evidence for a similar enhancement is also observed in psi(')-->pK(-)Lambda;+c.c. decays. The analysis is based on samples of 5.8x10(7)J/psi and 1.4x10(7)psi(') decays accumulated in the BES II detector at the Beijing Electron-Positron Collider.

20.
Zhongguo Zhong Xi Yi Jie He Za Zhi ; 14(12): 733-5, 1994 Dec.
Artigo em Chinês | MEDLINE | ID: mdl-7536499

RESUMO

The preventive and therapeutic effect of the traditional Chinese compound medicine Feixiankang (FXK) on the mice pulmonary fibrosis formation have been studied with the mice model. The level of LPO and the activity of SOD in the mice lung showed that LPO increased remarkably (P < 0.01), while the activity of SOD decreased significantly (P < 0.01) during the alveolar pneumonia period, although the LPO content had no significant change (P < 0.01) during experimental pulmonary fibrosis formation. In addition, the effect of FXK on the reducing of LPO was much stronger than that of the antioxidative agent Vitamin E. Also, FXK could improve the activity of SOD.


Assuntos
Medicamentos de Ervas Chinesas/farmacologia , Peróxidos Lipídicos/metabolismo , Fibrose Pulmonar/metabolismo , Superóxido Dismutase/metabolismo , Animais , Bleomicina , Masculino , Camundongos , Fibrose Pulmonar/induzido quimicamente
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