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1.
Small ; : e2402652, 2024 Jun 04.
Artigo em Inglês | MEDLINE | ID: mdl-38838056

RESUMO

The optimization of metal-support interactions is used to fabricate noble metal-based nanoclusters with high activity for hydrogen evolution reaction (HER) in acid media. Specifically, the oxygen-defective Mn3O4 nanosheets supported Pt nanoclusters of ≈1.71 nm in diameter (Pt/V·-Mn3O4 NSs) are synthesized through the controlled solvothermal reaction. The Pt/V·-Mn3O4 NSs show a superior activity and excellent stability for the HER in the acidic media. They only require an overpotential of 19 mV to drive -10 mA cm-2 and show negligible activity loss at -10 and -250 mA cm-2 for >200 and >60 h, respectively. Their Pt mass activity is 12.4 times higher than that of the Pt/C and even higher than those of many single-atom based Pt catalysts. DFT calculations show that their high HER activity arises mainly from the strong metal-support interaction between Pt and Mn3O4. It can facilitate the charge transfer from Mn3O4 to Pt, optimizing the H adsorption on the catalyst surface and promoting the evolution of H2 through the Volmer-Tafel mechanism. The oxygen vacancies in the V·-Mn3O4 NSs are found to be inconducive to the high activity of the Pt/V·-Mn3O4 NSs, highlighting the great importance to reduce the vacancy levels in V·-Mn3O4 NSs.

2.
Small Methods ; : e2400565, 2024 Jun 23.
Artigo em Inglês | MEDLINE | ID: mdl-38923872

RESUMO

This work utilizes defect engineering, heterostructure, pyridine N-doping, and carbon supporting to enhance cobalt-nickel selenide microspheres' performance in the oxygen electrode reaction. Specifically, microspheres mainly composed of CoNiSe2 and Co9Se8 heterojunction rich in selenium vacancies (VSe·) wrapped with nitrogen-doped carbon nanotubes (p-CoNiSe/NCNT@CC) are prepared by Ar/NH3 radio frequency plasma etching technique. The synthesized p-CoNiSe/NCNT@CC shows high oxygen reduction reaction (ORR) performance (half-wave potential (E1/2) = 0.878 V and limiting current density (JL) = 21.88 mA cm-2). The JL exceeds the 20 wt% Pt/C (19.34 mA cm-2) and the E1/2 is close to the 20 wt% Pt/C (0.881 V). It also possesses excellent oxygen evolution reaction (OER) performance (overpotential of 324 mV@10 mA cm-2), which even exceeds that of the commercial RuO2 (427 mV@10 mA cm-2). The density functional theory calculation indicates that the enhancement of ORR performance is attributed to the synergistic effect of plasma-induced VSe· and the CoNiSe2-Co9Se8 heterojunction. The p-CoNiSe/NCNT@CC electrode assembled Zinc-air batteries (ZABs) show a peak power density of 138.29 mW cm-2, outperforming the 20 wt% Pt/C+RuO2 (73.9 mW cm-2) and other recently reported catalysts. Furthermore, all-solid-state ZAB delivers a high peak power density of 64.83 mW cm-2 and ultra-robust cycling stability even under bending.

3.
ChemSusChem ; : e202400254, 2024 May 14.
Artigo em Inglês | MEDLINE | ID: mdl-38743510

RESUMO

Environmental pollution caused by persistent organic pollutants has imposed big threats to the health of human and ecological systems. The development of efficient methods to effectively degrade and remove these persistent organic pollutants is therefore of paramount importance. Photocatalytic persulfate-based advanced oxidation technologies (PS-AOTs), which depend on the highly reactive SO4 - radicals generated by the activation of PS to degrade persistent organic pollutants, have shown great promise. This work discusses the application and modification strategies of common photocatalysts in photocatalytic PS-AOTs, and compares the degradation performance of different catalysts for pollutants. Furthermore, essential elements impacting photocatalytic PS-AOTs are discussed, including the water matrix, reaction process mechanism, pollutant degradation pathway, singlet oxygen generation, and potential PS hazards. Finally, the existing issues and future challenges of photocatalytic PS-AOTs are summarized and prospected to encourage their practical application. In particular, by providing new insights into the PS-AOTs, this review sheds light on the opportunities and challenges for the development of photocatalysts with advanced features for the PS-AOTs, which will be of great interests to promote better fundamental understanding of the PS-AOTs and their practical applications.

4.
J Colloid Interface Sci ; 668: 525-539, 2024 Aug 15.
Artigo em Inglês | MEDLINE | ID: mdl-38691962

RESUMO

Economical oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) bifunctional catalysts with high activity aimed at replacing precious metal catalysts for rechargeable zinc-air batteries (ZABs) must be developed. In this study, a multiple hierarchical-structural material is developed using a facile dielectric barrier discharge (DBD) plasma surface treatment, solvothermal reaction, and high-temperature carbonization strategy. This strategy allows for the construction of nanosheets using nitrogen-doped carbon (NC) material-encapsulated ternary CoNiFe alloy nanoparticles (NPs) on a network of NC nanotubes (NCNTs), denoted as CoNiFe-NC@p-NCNTs. Precisely, the presence of abundant CoNiFe alloy NPs and the formation of M-N-C active sites created by transition metals (cobalt, nickel, and iron) coupled with NC can provide superior OER/ORR bifunctional properties. Moreover, the prepared NC layers with a multilevel pore structure contribute to a larger specific surface area, exposing numerous active sites and enhancing the uniformity of electron and mass movement. The CoNiFe0.08-NC@p-NCNTs show remarkable dual functionality for electrochemical oxygen reactions (ORR half-wave potential of 0.811 V, limiting current density of 5.73 mA cm-2 measured with a rotating disk electrode at a rotation speed of 1600 rpm, and OER overpotential of 351 mV at 10 mA cm-2), which demonstrates similar ORR performance to 20 wt% Pt/C and better OER performance than the commercial RuO2. A liquid ZAB prepared using the proposed material has excellent bifunctionality with an open-circuit voltage of 1.450 V and long-term cycling stability of 230 h@10 mA cm-2.

5.
Biomed Pharmacother ; 174: 116440, 2024 May.
Artigo em Inglês | MEDLINE | ID: mdl-38518605

RESUMO

Rheumatoid arthritis (RA) is a complex autoimmune inflammatory rheumatic disease characterized by an imbalance between immunological reactivity and immune tolerance. Regulatory T cells (Tregs), which play a crucial role in controlling ongoing autoimmunity and maintaining peripheral tolerance, have shown great potential for the treatment of autoimmune inflammatory rheumatic diseases such as RA. This review aims to provide an updated summary of the latest insights into Treg-targeting techniques in RA. We focus on current therapeutic strategies for targeting Tregs based on discussing their subsets, surface markers, suppressive function, and signaling pathways in RA.


Assuntos
Artrite Reumatoide , Biomarcadores , Transdução de Sinais , Linfócitos T Reguladores , Humanos , Artrite Reumatoide/imunologia , Artrite Reumatoide/tratamento farmacológico , Linfócitos T Reguladores/imunologia , Animais , Biomarcadores/metabolismo
6.
Biol Psychol ; 187: 108774, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38471619

RESUMO

There has been disagreement regarding the relationship among the three components (subjective experience, external performance, and physiological response) of emotional responses. To investigate this issue further, this study compared the effects of active and passive suppression of facial expressions on subjective experiences and event-related potentials (ERPs) through two experiments. The two methods of expression suppression produced opposite patterns of ERPs for negative emotional stimuli: compared with the free-viewing condition, active suppression of expression decreased, while passive suppression increased the amplitude of the late positive potential (LPP) when viewing negative emotional stimuli. Further, while active suppression had no effect on participants' emotional experience, passive suppression enhanced their emotional experience. Among the three components of emotional responses, facial expressions are more closely related to the physiological response of the brain than to subjective experience, and whether the suppression was initiated by participants determines the decrease or increase in physiological response of the brain (i.e. LPP). The findings revealed the important role of individual subjective initiative in modulating the relationship among the components of emotional response, which provides new insights into effectively emotional regulation.


Assuntos
Regulação Emocional , Expressão Facial , Humanos , Potenciais Evocados/fisiologia , Emoções/fisiologia , Encéfalo/fisiologia , Eletroencefalografia
7.
Br J Psychol ; 115(1): 20-39, 2024 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-37401616

RESUMO

People often form first impressions of others based on face and/or voice cues. This study aimed to compare the first impressions formed under these two cues. First, we compared free descriptions based on face and voice cues and found differences in the content and frequency of the personality words. We then compiled three wordlists used for face-based and voice-based first impression evaluations separately or simultaneously. Second, using these wordlists, we compared face-based and voice-based first impression ratings and found that both had significant intra-rater and inter-rater reliability. However, using the mean of the actors' self-rating and their acquaintance rating as the validity criterion, only the ratings of 'ingenuous' and 'mature' traits in the face-based first impression evaluation were significantly correlated with the validity criterion. Factor analysis revealed that face-based first impression had the dimensions of capability and approachability, while voice-based first impression had capability, approachability and reliability. The findings indicate that stable first impressions can be formed by either face or voice cues. However, the specific composition of impressions will vary between the cues. These results also provide a foundation for studying first impressions formed by an integrated perception of voice and face cues.


Assuntos
Voz , Humanos , Reprodutibilidade dos Testes , Personalidade , Sinais (Psicologia) , China
8.
Chem Rec ; 24(1): e202300206, 2024 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-37736673

RESUMO

The development of sodium-ion battery (SIB) anodes is still hindered by their rapid capacity decay and poor rate capabilities. Although there have been some new materials that can be used to fabricate stable anodes, SIBs are still far from wide applications. Strategies like nanostructure construction and material modification have been used to prepare more robust SIB anodes. Among all the design strategies, the hollow structure design is a promising method in the development of advanced anode materials. In the past decade, research efforts have been devoted to modifying the synthetic route, the type of templates, and the interior structure of hollow structures with high capacity and stability. A brief introduction is made to the main material systems and classifications of hollow structural materials first. Then different morphologies of hollow structural materials for SIB anodes from the latest reports are discussed, including nanoboxes, nanospheres, yolk shells, nanotubes, and other more complex shapes. The most used templates for the synthesis of hollow structrual materials are covered and the perspectives are highlighted at the end. This review offers a comprehensive discussion of the synthesis of hollow structural materials for SIB anodes, which could be potentially of use to research areas involving hollow materials design for batteries.

9.
Small Methods ; 8(3): e2301342, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-37997209

RESUMO

The carbon nanotubes (CNTs) supported amorphous Sb doped substoichiometric tin dulfide (Sb─SnSx ) with a carbon coating (the C/Sb─SnSx @CNTs-500) is reported to be an efficient anode material for K+ storage. The formation of the C/Sb─SnSx @CNTs-500 is simply achieved through the thermally induced desulfurization of tin sulfide via a controlled annealing of the C/Sb─SnS2 @CNTs at 500 °C. When used for the K+ storage, it can deliver stable reversible capacities of 406.5, 305.7, and 238.4 mAh g-1 at 0.1, 1.0, and 2.0 A g-1 , respectively, and shows no capacity drops when potassiated/depotassiated at 1.0 and 2.0 A g-1 for >3000 and 2400 cycles, respectively. Even at 10, 20, and 30 A g-1 , it can still deliver stable reversible capacities of 138.5, 85.1, and 73.8 mAh g-1 , respectively. The unique structure, which combines the advantageous features of carbon integration/coating, metal doping, and desulfurization-induced amorphous structure, is the main origin of the high performance of the C/Sb─SnSx @CNTs-500. Specifically, the carbon integration/coating can increase the electric conductivity and stability of the C/Sb─SnSx @CNTs-500. The density function theory calculation indicates that the Sb doping and the desulfurization can facilitate the potassiation and increase the electric conductivity of Sb─SnSx . Additionally, the desulfurization can increase the K+ diffusivity in Sb─SnSx .

10.
Adv Mater ; 36(13): e2306934, 2024 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-38135663

RESUMO

The development of cost-effective catalysts for oxygen evolution reaction (OER) in acidic media is of paramount importance. This work reports that Sr-doped solid solution structural ultrafine IrMnO2 nanoparticles (NPs) (≈1.56 nm) on the carbon nanotubes (Sr-IrMnO2/CNTs) are efficient catalysts for the acidic OER. Even with the Ir use dosage 3.5 times lower than that of the commercial IrO2, the Sr-IrMnO2/CNTs only need an overpotential of 236.0 mV to drive 10.0 mA cm-2 and show outstanding stability for >400.0 h. Its Ir mass activity is 39.6 times higher than that of the IrO2 at 1.53 V. The solid solution and Sr-doping structure of Sr-IrMnO2 are the main origin of the high catalytic activity and excellent stability of the Sr-IrMnO2/CNTs. The density function theory calculations indicate that the solid solution structure can promote strong electronic coupling between Ir and Mn, lowering the energy barrier of the OER rate-determining step. The Sr-doping can enhance the stability of Ir against the chemical corrosion and demetallation. Water electrolyzers and proton exchange membrane water electrolyzers assembled with the Sr-IrMnO2/CNTs show superb performance and excellent durability in the acid media.

11.
Heliyon ; 9(7): e18341, 2023 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-37539095

RESUMO

To explore the mechanism of emotional words semantic satiation effect on facial expression processing, participants were asked to judge the facial expression (happiness or sadness) after an emotional word ((cry) or (smile)) or a neutral word ((Ah), baseline condition) was presented for 20 s. The results revealed that participants were slower in judging valence-congruent facial expressions and reported a more enlarged (Experiment 1) and prolonged (Experiment 2) N170 component than the baseline condition. No significant difference in behavior and N170 appeared between the valence-incongruent and the baseline condition. However, the amplitude of LPC (Late Positive Complex) under both valence-congruent/incongruent conditions was smaller than the baseline condition. It indicates that, in the early stage, the impeding effect of satiated emotional words is specifically constrained to facial expressions with the same emotional valence; in the late stage, such an impeding effect might spread to facial expressions with the opposite valence of the satiated emotional word.

12.
Small ; 19(46): e2304076, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37464549

RESUMO

Plasma treatment and reduction are used to synthesize Pt nanoparticles (NPs) on nitrogen-doped carbon nanotubes (p-Pt/p-NCNT) with a low Pt content. In particular, the plasma treatment is used to treat the NCNT to give it with more surface defects, facilitating a better growth of the Pt NPs, while the plasma reduction produces the Pt NPs with a reduced fraction of the surface atoms at the high oxidation states, increasing the catalytic activities of the p-Pt@p-NCNT. Even at the low Pt content (7.8 wt.%), the p-Pt@p-NCNT shows superior catalytic activities and good stabilities for methanol oxidation reaction (MOR) and oxygen reduction reaction (ORR). The density functional theory (DFT) calculations indicate that the defects generated in the plasma treatment can help the growth of the Pt NPs on the NCNTs, leading to the stronger electronic coupling between Pt and NCNT and the increased stability of the catalyst. The plasma reduction can give the Pt NPs with optimized surface oxidation states, decreasing the energy barriers of the rate-determining steps for MOR and ORR. When used as the anode and cathode catalysts for the direct methanol fuel cells (DMFCs), the p-Pt@p-NCNT exhibits a higher maximum power density of 81.9 mW cm-2  at 80 °C and shows good durability.

13.
J Colloid Interface Sci ; 649: 36-48, 2023 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-37331108

RESUMO

Developing high-efficient, good-durability, and low-cost bifunctional non-precious metal catalysts for both oxygen reduction reaction (ORR) and oxygen evolution reaction (OER) is urgent and significant for promoting the practical rechargeable zinc-air batteries (RZABs). Herein, N-doped carbon coated Co/FeCo@Fe(Co)3O4 heterojunction rich in oxygen vacancies derived from metal-organic frameworks (MOFs) is successfully constructed by O2 plasma treatment. The phase transition of Co/FeCo to FeCo oxide (Fe3O4/Co3O4) mainly occurs on the surface of nanoparticles (NPs) during the O2 plasma treatment, which can form rich oxygen vacancies simultaneously. The fabricated catalyst P-Co3Fe1/NC-700-10 with optimal O2 plasma treatment time of 10 min can reduce the potential gap between the OER and ORR to 760 mV, which is much lower than commercial 20% Pt/C + RuO2 (910 mV). Density functional theory (DFT) calculation indicates that the synergistic coupling between Co/FeCo alloy NPs and FeCo oxide layer can promote the ORR/OER performance. Both liquid electrolyte RZAB and flexible all-solid-state RZAB using P-Co3Fe1/NC-700-10 as the air-cathode catalyst display high power density, specific capacity and excellent stability. This work provides an effective idea for the development of high performance bifunctional electrocatalyst and the application of RZABs.

14.
Int J Psychophysiol ; 183: 53-60, 2023 01.
Artigo em Inglês | MEDLINE | ID: mdl-36410466

RESUMO

Although evidence for cultural variants in facial expression decoding is accumulating, the other-race effect in facial expression processing and its neural correlates are still unclear. We investigated this question with a fully balanced design, in which a group of East Asian and a group of European Caucasian women categorized pictures of sad, happy, angry, and neutral facial expressions posed by individuals of their own-race and the other-race. Results revealed a disadvantage in categorizing expressions of anger in other-race faces in both samples, and for sad expressions in the European sample only. Partially consistent, East Asian participants showed longer latency of the N170 component in the event-related potential (ERP) and European Caucasian participants showed larger N170 amplitudes to other-race faces. The late positive complex in the ERP was less distinguishable among other-race facial expressions. Therefore, the present study observed an other-race effect in early and late stages of face processing, reflecting less efficient structural encoding and less elaborate processing for other-race than own-race faces.


Assuntos
Emoções , Reconhecimento Facial , Humanos , Feminino , Emoções/fisiologia , Expressão Facial , Eletroencefalografia , Comparação Transcultural , Potenciais Evocados/fisiologia , Reconhecimento Facial/fisiologia
15.
Front Chem ; 10: 1073566, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36465867

RESUMO

Direct methanol fuel cells (DMFCs) have been the focus of future research because of their simple structure, abundant fuel sources, high energy conversion efficiency and low cost. Among the components in DMFC, the activity and stability of the cathode catalyst is the key to the performance and lifetime of the DMFCs. Oxygen reduction reaction (ORR) is an important electrode reaction on DMFC cathode. It is known that Pt is widely used in the fabrication of ORR catalysts, but the limited earth storage of Pt and its high price limit the use of Pt-based commercial catalysts in DMFCs. To overcome these problems, advances have been made on new low Pt-based catalysts and Pt-free catalysts in recent years. In this article, the development of novel ORR catalysts and the carbon supports is reviewed and discussed.

16.
Small ; 18(30): e2201467, 2022 Jul.
Artigo em Inglês | MEDLINE | ID: mdl-35699694

RESUMO

This work reports an amorphization and partial desulfurization method to improve the performance of sulfide-based materials for Na+ storage. Specifically, the polypyrrole derived carbon coated amorphous substoichiometric tin sulfide supported on aminated carbon nanotubes (PPY-C@SnSx /ACNTs) with amorphized and substoichiometric tin sulfide (SnSx ) is synthesized by simply thermal annealing the PPY-C@SnS2 /ACNTs. The PPY-C@SnSx /ACNTs shows stable reversible capacities of 410.2 mAh g-1 for Na+ storage at 0.1 A g-1 and excellent rate capacities of 270.2, 235.5, 217.4, and 210.0 mAh g-1 at 5.0, 10.0, 20.0, and 30.0 A g-1 , respectively. Nearly zero drops on the reversible capacities can be observed when it is sodiated/desodiated at 2.0, 5.0, and 10.0 A g-1 for up to 1000, 6500, 8000 cycles, respectively. Its outstanding rate capacities and degradation-free cycling stabilities mainly arise from the amorphized and substoichiometric structure of SnSx , which improve the reversible capacities and Na+ diffusivities of the PPY-C@SnSx /ACNTs. The density functional theory (DFT) calculations indicate that the partial desulfurization can improve the electric conductivity and promote the sodiation/desodiation of SnSx . It explains why the PPY-C@SnSx /ACNTs can exhibit high performance for Na+ storage well.

17.
J Oncol ; 2022: 5887671, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-35035481

RESUMO

OBJECTIVE: To investigate the effect of OA on proliferation, migration, and epithelial-mesenchymal transition (EMT) of ovarian cancer cells by inhibiting UNC5B and to study its mechanism. METHODS: TCGA database was used to analyze the expression of UNC5B in ovarian cancer and its relationship with prognosis. The expression of UNC5B in ovarian cancer cells was detected by qPCR assay. qRT-PCR was used to detect the changes of EMT markers after different treatments. CCK-8 assay was used to detect cell proliferation, transwell assay was used to evaluate cell migration, and clonogenesis assay was used to evaluate the effect of UNC5B on ovarian cancer cell proliferation. Meanwhile, the synergistic effect of OA on niraparib was evaluated. RESULTS: UNC5B was highly expressed in ovarian cancer, and its expression was negatively correlated with the prognosis of ovarian cancer patients. UNC5B was highly expressed in ovarian cancer cells SKOV3 and OVCA420 compared with normal ovarian epithelial cells. In addition, silencing UNC5B inhibits the proliferation, invasion, clonogenesis, and EMT processes of ovarian cancer cells. OA inhibits proliferation, invasion, and clonogenesis of ovarian cancer cells by inhibiting UNC5B and increases the antitumor activity of niraparib. CONCLUSION: UNC5B acts as an oncogenic gene in ovarian cancer. OA inhibits ovarian cancer cell proliferation, migration, and EMT by targeting UNC5B and increases the antitumor effect of niraparib. UNC5B is expected to be a new potential therapeutic target for ovarian cancer. OA may be used as an antitumor drug and deserves further study.

18.
Nanoscale ; 13(30): 12788-12817, 2021 Aug 14.
Artigo em Inglês | MEDLINE | ID: mdl-34477767

RESUMO

As a clean energy carrier, hydrogen has priority in decarbonization to build sustainable and carbon-neutral economies due to its high energy density and no pollutant emission upon combustion. Electrochemical water splitting driven by renewable electricity to produce green hydrogen with high-purity has been considered to be a promising technology. Unfortunately, the reaction of water electrolysis always requires a large excess potential, let alone the large-scale application (e.g., >500 mA cm-2 needs a cell voltage range of 1.8-2.4 V). Thus, developing cost-effective and robust transition metal electrocatalysts working at high current density is imperative and urgent for industrial electrocatalytic water splitting. In this review, the strategies and requirements for the design of self-supported electrocatalysts are summarized and discussed. Subsequently, the fundamental mechanisms of water electrolysis (OER or HER) are analyzed, and the required important evaluation parameters, relevant testing conditions and potential conversion in exploring electrocatalysts working at high current density are also introduced. Specifically, recent progress in the engineering of self-supported transition metal-based electrocatalysts for either HER or OER, as well as overall water splitting (OWS), including oxides, hydroxides, phosphides, sulfides, nitrides and alloys applied in the alkaline electrolyte at large current density condition is highlighted in detail, focusing on current advances in the nanostructure design, controllable fabrication and mechanistic understanding for enhancing the electrocatalytic performance. Finally, remaining challenges and outlooks for constructing self-supported transition metal electrocatalysts working at large current density are proposed. It is expected to give guidance and inspiration to rationally design and prepare these electrocatalysts for practical applications, and thus further promote the practical production of hydrogen via electrochemical water splitting.

19.
Gynecol Obstet Invest ; 86(4): 361-369, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34464954

RESUMO

OBJECTIVES: The objective of this study was to determine the relationship between the levels of stress biomarkers in cord blood and pre-eclampsia (PE) in a hospital-based population of pregnant patients and evaluate the effects on pregnancy outcomes. DESIGN: This was an observational, case-control study. Participants/Materials, Setting, Methods: This case-control study included 282 patients with severe PE and 534 women with normal pregnancy. The umbilical cord was collected at delivery and tested for malonaldehyde (MDA), reactive oxygen species (ROS), superoxide dismutase, and homocysteine (Hcy) analysis. We performed a univariate general linear regression model analysis to control potential confounders and determined the underlying influencing factors for high MDA and ROS. A receiver operating characteristic curve analysis was conducted to determine the cutoff values for identifying severe PE. Further, the severe PE group was divided into the low- or high-MDA and low- or high-ROS subgroups according to the cutoff values. Finally, we created logistic regression models to estimate the adjusted odds ratio for each perinatal outcome in the high-MDA and high-ROS subgroup. RESULTS: The levels of MDA and ROS levels were higher in women with severe PE than in normotensive pregnant patients. However, when adjusted for cord blood Hcy levels, the difference was insignificant. Additionally, both MDA (r = 0.359, p < 0.001) and ROS (r = 0.473, p < 0.001) were positively correlated with the cord blood Hcy level. The areas under the curve of MDA and ROS levels were 0.65 (95% confidence interval [CI]: 0.60-0.69) and 0.88 (95% CI: 0.86-0.90), respectively. Higher MDA and ROS levels were associated with increased risks of a low Apgar score, admission to the NICU, and assisted ventilation for the newborn. LIMITATIONS: The study design led to the exclusion of several participants. CONCLUSIONS: Increased levels of oxidative stress markers in the cord blood might be significantly associated with negative effects on newborns. High levels of Hcy in the cord blood might be associated with elevated MDA and ROS concentrations in women with severe PE.


Assuntos
Pré-Eclâmpsia , Biomarcadores , Estudos de Casos e Controles , Feminino , Sangue Fetal , Humanos , Recém-Nascido , Mães , Estresse Oxidativo , Gravidez
20.
Front Psychol ; 12: 638398, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34194357

RESUMO

Numerous studies have shown that facial expressions influence trait impressions in the Western context. There are cultural differences in the perception and recognition rules of different intensities of happy expressions, and researchers have only explored the influence of the intensity of happy expressions on a few facial traits (warmth, trustworthiness, and competence). Therefore, we examined the effect of different intensities of Chinese happy expressions on the social perception of faces from 11 traits, namely trustworthiness, responsibility, attractiveness, sociability, confidence, intelligence, aggressiveness, dominance, competence, warmth, and tenacity. In this study, participants were asked to view a series of photographs of faces with high-intensity or low-intensity happy expressions and rate the 11 traits on a 7-point Likert scale (1 = "not very ××," 7 = "very ××"). The results indicated that high-intensity happy expression had higher-rated scores for sociability and warmth but lower scores for dominance, aggressiveness, intelligence, and competence than the low-intensity happy expression; there was no significant difference in the rated scores for trustworthiness, attractiveness, responsibility, confidence, and tenacity between the high-intensity and low-intensity happy expressions. These results suggested that, compared to the low-intensity happy expression, the high-intensity happy expression will enhance the perceptual outcome of the traits related to approachability, reduce the perceptual outcome of traits related to capability, and have no significant effect on trustworthiness, attractiveness, responsibility, confidence, and tenacity.

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