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5.
Diagnostics (Basel) ; 6(4)2016 Sep 30.
Artigo em Inglês | MEDLINE | ID: mdl-27706025

RESUMO

Non-small cell lung cancer (NSCLC) is the leading cause of cancer mortality worldwide and its prognosis remains poor. Molecular imaging with 18F-FDG PET/CT can metabolically characterize the nature of lesions as benign or malignant, allowing a better staging at the diagnosis of this kind of patient. This advantage can also be applied in the re-staging due to the suspicion of recurrent disease. Many patients have a recurrence of the disease, including surgically treated patients. In the current context, with new personalized oncological treatments, the surveillance for recurrence and its accurate diagnosis are crucial to improve their survival. In this paper, we revise the current knowledge about the clinical and molecular factors related to the recurrent disease. In the context of new, promising, available personalized treatments, the role of molecular imaging with PET/CT and 18F-FDG and non-18F-FDG radiotracers in the follow-up of NSCLC-treated patients is especially attractive and interesting.

6.
Eur Urol ; 59(2): 297-9, 2011 Feb.
Artigo em Inglês | MEDLINE | ID: mdl-19524352

RESUMO

A cyst infection was suspected in a patient who was on haemodialysis for renal failure secondary to hepatorenal polycystic disease with persistent fever and pain in right hypochondrium despite antibiotherapy. Radiologic exams (ultrasonography, computed tomography [CT]), however, did not show signs of infection. For surgical removal of the infected cyst, a precise location was required. This report shows how functional imaging, gallium citrate Ga 67 scan, and fluorine F 18 fluorodeoxyglucose (FDG) positron emission tomography (PET) revealed which cyst was infected; however, the fused image provided by PET/CT showed the precise, required location. The infected cyst was located on the right kidney. A week later, after nephrectomy, all symptoms disappeared.


Assuntos
Abscesso/diagnóstico por imagem , Síndrome Hepatorrenal/diagnóstico por imagem , Rim Policístico Autossômico Dominante/diagnóstico por imagem , Tomografia por Emissão de Pósitrons/métodos , Abscesso/cirurgia , Citratos , Feminino , Fluordesoxiglucose F18 , Gálio , Síndrome Hepatorrenal/cirurgia , Humanos , Pessoa de Meia-Idade , Rim Policístico Autossômico Dominante/cirurgia , Tomografia Computadorizada por Raios X
7.
Clin Nucl Med ; 32(12): 952-3, 2007 Dec.
Artigo em Inglês | MEDLINE | ID: mdl-18030051

RESUMO

We report the case of a 75-year-old man, in whom Y-90 ibritumomab was requested because of relapse of blastoid variant mantle cell lymphoma diagnosed in 1995. Before Y-90 ibritumomab treatment, FDG PET and In-111 ibritumomab scintigraphy with planar views at 24 hours, 48 hours, and 5 days, including SPECT, were performed. Discordant information between both examinations was observed as, in addition to the lesions detected by In-111 ibritumomab imaging, FDG PET detected lesions that did not take up the ibritumomab. The discrepancy shown by both radiotracers has to be kept in mind before planning treatment with Y-90 ibritumomab, and for the correct evaluation of treatment response.


Assuntos
Anticorpos Monoclonais/uso terapêutico , Linfoma de Célula do Manto/radioterapia , Radioimunoterapia , Idoso , Fluordesoxiglucose F18/farmacocinética , Humanos , Radioisótopos de Índio/farmacocinética , Linfoma de Célula do Manto/patologia , Masculino , Tomografia por Emissão de Pósitrons , Tomografia Computadorizada de Emissão de Fóton Único , Tomografia Computadorizada por Raios X
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