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Medicine (Baltimore) ; 99(43): e22940, 2020 Oct 23.
Artigo em Inglês | MEDLINE | ID: mdl-33120854

RESUMO

RATIONALE: Acute encephalopathy with biphasic seizures and late reduced diffusion (AESD) has been reported almost exclusively in the Japanese population. PATIENT CONCERNS: A 17-month-old male patient presented with fever and seizures, and subsequently fell into a coma. On the second day, he recovered consciousness. On the fourth day, he developed complex partial seizures and fell into a coma again. On day 10, the fever and seizures subsided. Head computed tomography on the first day showed no abnormalities. Brain diffusion-weighted images on the fourth day revealed reduced diffusion in the bilateral subcortical white matter. DIAGNOSIS: A diagnosis of AESD was made. INTERVENTIONS: The patient was treated with corticosteroids and intravenous immunoglobulin. OUTCOMES: At the 4-month follow-up, the patient was able to walk independently, and the epileptic seizures were well controlled. LESSONS: AESD is a rare entity, and treatment with corticosteroids and intravenous immunoglobulin can lead to a favorable prognosis. Clinicians should be aware of this condition, and clinicoradiological features can suggest the diagnosis.


Assuntos
Encefalopatias/complicações , Imagem de Difusão por Ressonância Magnética/métodos , Convulsões/etiologia , Doença Aguda , Corticosteroides/uso terapêutico , Encefalopatias/diagnóstico , Encefalopatias/tratamento farmacológico , Coma/diagnóstico , Coma/etiologia , Quimioterapia Combinada , Febre/diagnóstico , Febre/etiologia , Humanos , Imunoglobulinas Intravenosas/uso terapêutico , Lactente , Masculino , Convulsões/diagnóstico , Convulsões/fisiopatologia , Tomografia Computadorizada por Raios X/métodos , Resultado do Tratamento , Substância Branca/diagnóstico por imagem , Substância Branca/patologia
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