Digital transformation and carbon intensity reduction in transportation industry: Empirical evidence from a global perspective.

Digital transformation has become an inevitable trend in industrial development, but research on its environmental benefits has not been conducted in-depth. This paper focuses on the impact and mechanisms of the digital transformation of the transportation industry on its carbon intensity. Empirical tests are conducted based on the panel data of 43 economies from 2000 to 2014. The results show that the digital transformation of the transportation industry reduces its carbon intensity, but only the digital transformation that relies on domestic digital sources is significant. Second, technological progress, upgrading the industry's internal structure and improving energy consumption are the main channels through which the digital transformation of the transportation industry reduces its carbon intensity. Third, in terms of subdividing industries, the digital transformation of basic transportation has a more significant effect on reducing carbon intensity. For segmentation digitization, the carbon intensity reduction from digital infrastructure is more significant. This paper serves as a reference for countries to formulate development policies for the transportation industry and implement the Paris Agreement.

How ICT development affects manufacturing carbon emissions: theoretical and empirical evidence.

There is a broad consensus that information and communication technology (ICT) development contributes to economic growth, but its environmental benefits have not been thoroughly studied. This paper explores the impact and mechanisms of ICT development on manufacturing carbon emissions. We first conducted empirical tests based on panel data from 18 manufacturing sectors in 42 countries from 2000 to 2014. The results show that domestic ICT development reduces manufacturing carbon emissions, but the effect is only significant in sectors with high ICT embedded. Second, technological progress, industrial internal structure upgrading, energy consumption intensification, and low carbonization are the main channels for ICT development and embedding to reduce manufacturing carbon emissions. Third, the carbon emissions from manufacturing, which are deeply embedded by ICT, will decrease as the position of ICT forward GVCs improves, and increase as the position of backward GVCs increases. In addition, ICT development has a more significant impact on reducing carbon emissions in high-tech manufacturing. This paper has enriched research on the environmental benefits of ICT development and has been informative and insightful for countries in formulating industrial development policies and implementing the Paris Agreement.

Disseminated Intravascular Coagulation in Pediatric Scoliosis Surgery: A Systematic Review.

BACKGROUND: Disseminated intravascular coagulation (DIC) is a rare but serious complication of pediatric scoliosis surgery; sparse current evidence warrants more information on causality and prevention. This systematic review sought to identify incidence of DIC in pediatric patients during or shortly after corrective scoliosis surgery and identify any predictive factors for DIC. METHODS: Medline/PubMed, EMBASE, and Ovid databases were systematically reviewed through July 2017 to identify pediatric patients with DIC in the setting of scoliosis surgery. Patient demographics, medical history, surgery performed, clinical course, suspected causes of DIC, and outcomes were collected. RESULTS: Eleven studies met inclusion criteria. Thirteen cases from 1974 to 2012 (mean age: 15.3 ± 4.3 years, 72% women) were identified, with neuromuscular (n = 7; 54%) scoliosis as the most common indication. There were no prior bleeding disorder histories; all preoperative labs were within normal limits. Procedures included 8 posterior segmental fusions (54%), 3 Harrington rods (31%), 1 Cotrel-Dubousset, and 1 unit rod. Eight patients experienced DIC intraoperatively and 5 patients experienced DIC postoperatively. Probable DIC causes included coagulopathy following intraoperatively retrieved blood reinfusion, infection from transfusion, rhabdomyolysis, hemostatic matrix application, heparin use, and hypovolemic shock. Most common complications included increased intraoperative blood loss (n = 8) and hypotension (n = 7). The mortality rate was 7.69%; one fatality occurred in the acute postoperative period. CONCLUSIONS: Prior bleeding disorder status notwithstanding, this review identified preliminary associations between variables during corrective scoliosis surgery and DIC incidence among pediatric patients, suggesting multiple etiologies for DIC in the setting of scoliosis surgery. Further investigation is warranted to quantify associated risk. CLINICAL RELEVANCE: This study brings awareness to a previously rarely discussed complication of pediatric scoliosis surgery. Further cognizance of DIC by scoliosis surgeons may help identify and prevent causes thereof.

Diversity of 16S rRNA genes within individual prokaryotic genomes.

Analysis of intragenomic variation of 16S rRNA genes is a unique approach to examining the concept of ribosomal constraints on rRNA genes; the degree of variation is an important parameter to consider for estimation of the diversity of a complex microbiome in the recently initiated Human Microbiome Project (http://nihroadmap.nih.gov/hmp). The current GenBank database has a collection of 883 prokaryotic genomes representing 568 unique species, of which 425 species contained 2 to 15 copies of 16S rRNA genes per genome (2.22 +/- 0.81). Sequence diversity among the 16S rRNA genes in a genome was found in 235 species (from 0.06% to 20.38%; 0.55% +/- 1.46%). Compared with the 16S rRNA-based threshold for operational definition of species (1 to 1.3% diversity), the diversity was borderline (between 1% and 1.3%) in 10 species and >1.3% in 14 species. The diversified 16S rRNA genes in Haloarcula marismortui (diversity, 5.63%) and Thermoanaerobacter tengcongensis (6.70%) were highly conserved at the 2 degrees structure level, while the diversified gene in B. afzelii (20.38%) appears to be a pseudogene. The diversified genes in the remaining 21 species were also conserved, except for a truncated 16S rRNA gene in "Candidatus Protochlamydia amoebophila." Thus, this survey of intragenomic diversity of 16S rRNA genes provides strong evidence supporting the theory of ribosomal constraint. Taxonomic classification using the 16S rRNA-based operational threshold could misclassify a number of species into more than one species, leading to an overestimation of the diversity of a complex microbiome. This phenomenon is especially seen in 7 bacterial species associated with the human microbiome or diseases.