RESUMO
Wegener's granulomatosis is an uncommon disease characterized by necrotizing granulomatous lesions in the respiratory tract, generalized focal necrotizing vasculitis, and focal necrotizing glomerulonephritis. Ocular complications may occur secondary to contiguous granulomatous sinusitis or as a result of focal vasculitis and are encountered in 40 ~ 50% of cases of generalized form. We reviewed 5 cases of Wegener's granulomatosis which were confirmed by clinlcal findings and histopathologic examination of biopsy specimens, which revealed one or more ocular complications such as lid swelling, corneal degeneration, staphyloma, corneal ulcer, and nasolacrimal duct obstruction. The patterns of ocular disease, its relationship to systemic involvement, diagnostic method, and the response to therapy are discussed.
Assuntos
Biópsia , Úlcera da Córnea , Glomerulonefrite , Ducto Nasolacrimal , Sistema Respiratório , Sinusite , Vasculite , Granulomatose com PoliangiiteRESUMO
Ocular toxocariasis in human is a rare disease, which occurs by ingesting infective ova accidentally. Clinically, patients with ocular toxocariasis are divided into 3 groups: group 1 consisted of those with diffuse destructive endophthalmitis, group 2 included those focal posterior pole granuloma, group 3 was made up of those with peripheral inflammatory masses in a relatively quiet eye. We experienced a 17 year-old female whose left eye exhibited a dense white elevated inflammatory mass over the macular area and connective-tissue strands extending from the mass to vitreous and surrounding retina. We report this case with a review of literature, but we couldn't get the aid of the ELISA test for antibody of Toxocara canis.