Characteristics of out-of-hospital acute coronary heart disease deaths of Beijing permanent residents at the age of 25 or more from 2007 to 2009 / 中华心血管病杂志

<p><b>OBJECTIVE</b>To analyze the characteristics of out-of-hospital acute coronary heart disease (CHD) deaths in Beijing permanent residents at the age of 25 or more from 2007 to 2009.</p><p><b>METHODS</b>We analyzed the gender, age, geographical distribution, occupation, marital status and the extent of different education characteristics of out-of-hospital acute CHD deaths of the Beijing permanent residents at the age of 25 or more from 2007 to 2009 using the mortality information database from the Beijing Vital Registration Monitoring System.</p><p><b>RESULTS</b>Of the total 41 732 acute CHD deaths, 30 159 (72.27%) died out of hospital and out-of-hospital mortality was 2.61 times higher than in-hospital mortality. Majority out-of-hospital death occurred in males (72.30%, 16 068/22 224), in 25 - 34 years old people (91.75%, 89/97), in residents living in remoter suburbs and counties (82.43%, 13 513/16 393), in rural population (89.50%, 10 017/11 192), in non-marital single (80.76%, 592/733) and in people less than five-years of schooling (83.95%, 11 388/13 565). Most out-of-hospital acute CHD death occurred at home (78.80%, 23 765/30 159).</p><p><b>CONCLUSIONS</b>Out-of hospital acute CHD mortality is high in Beijing permanent residents at the age of 25 and over from 2007 to 2009. Male, 25 - 34 years old, living in outer suburbs and counties, rural population, non-marital single, and less education years are major risk factors for out-of-hospital acute CHD death.</p>

Analysis of the quality of notifiable infectious disease report in Beijing medical treatment organizations / 中华预防医学杂志

<p><b>OBJECTIVE</b>To evaluate the quality of the infectious diseases reporting via network in Beijing hospitals and to filtrate factors that affect the reporting quality.</p><p><b>METHODS</b>We collected 5536 infectious disease cases randomly and investigated 52 medical treatment organizations. Information was collected by field questionnaire survey, interview and gathering routine reporting data for analyzing the quality.</p><p><b>RESULTS</b>The result showed that the timeliness of the 52 medical treatment organizations was 94.18%, the consistency was 80.84%, the completeness was 88.47%, and the misreport was 13.73%. The reporting quality of the second level hospitals was higher than that of the first level hospitals, township health centers and the third level hospitals. The reporting quality of urban hospitals was higher than that of the suburb hospitals. The reporting quality of outpatient and inpatient departments was higher than that of the laboratory. The laboratory was the primary part of underreporting.</p><p><b>CONCLUSION</b>Strengthening guidance, training and paying attention to each weak portion would certainly ameliorate the quality of infectious diseases reporting via network.</p>

Asialofetuin-hTERT-TK/GCV targeted gene therapy and its bystander effect on HepG2 / 中华肝脏病杂志

<p><b>OBJECTIVE</b>To observe the targeted therapeutic effects of plasmid AF-pGL3-hTERT-TK on HepG2 cells.</p><p><b>METHODS</b>HepG2 cells were cultured and pGL3-hTERT-TK and AF-liposome were constructed. HepG2 and L02 cells were transfected with AF-pGL3-hTERT-TK. The growth, apoptosis of the cells and the bystander effects were studied using liquid scintillation analysis and tunnel and flow cytometry.</p><p><b>RESULTS</b>After the suicide gene was inserted into the downstream of hTERT, TK was effectively driven by the hTERT promoter, making the TK highly expressed in the HepG2 cells. The AF made the therapeutic gene enter the HepG2 cells more easily by recognizing and combining the ASGPR receptor protein on the HepG2 cell surfaces and induced their apoptosis and suicide with bystander effect. The apoptosis rate was 85%+/-3% in the HepG2 cells whereas in the normal L02 hepatic cells it was 16%+/-2%.</p><p><b>CONCLUSION</b>AF-pGL3-hTERT-TK can target and attack HepG2 cells and has almost no influence on normal L02 hepatic cells. AF-pGL3-hTERT-TK has a potential in the treatment of hepatocellular carcinomas.</p>

Effect of Proprioception Disturbance on Activities of Daily Living after Stroke / 中国康复理论与实践

@#ObjectiveTo observe the effect of proprioception disturbance on the activities of daily living (ADL) after stroke.Methods67 stroke patients were divided into group A (32 cases with proprioception disturbance) and group B (35 cases without proprioception disturbance) according to if having proprioception disturbance. All patients of two groups were treated with routine medicine and rehabilitation treatment. Modified Barthel Index (MBI) was used to assess ADL when admission and 8 weeks later.ResultsIn all 67 stroke patients, the incidence of proprioception disturbance was 48.6%. After 8 weeks treatment, MBI scores of both groups improved significantly (P<0.05～0.01) and the average scores of group A was obviously lower than that of group B (P<0.05).ConclusionProprioception disturbance has bad affect on recovery of ADL after stroke obviously. Examination for proprioception disturbance should be performed in early stage after stroke and rehabilitation training should be carried on as soon as possible.

Effects of cluster needling of scalp point combined with rehabilitation techniques on movement disturbance after acute cerebral infarction / 中国康复理论与实践

@#ObjectiveTo explore the effect of cluster needing of scalp point combined with rehabilitation techniques on acute cerebral infarction patient's movement disturbance.MethodsFugl-Meyer Measure, Bathel Index, Nerve function disturbance and clinical effect assessment methods were used to assess the motion function and daily living activity of cluster needling of scalp point group, rehabilitation group and cluster needling of scalp point combined with rehabilitation group.ResultsThe motion function and daily living activity of the cluster needling of scalp point combined with rehabilitation group patients were superior to cluster needling of scalp point group patients and rehabilitation group patients (P<0.01,P<0.05). The total effective rate can reach to 97.14%. Otherwise, cluster needling of scalp point combined with rehabilitation could also prevent food drop or inversion, subluxation of acromioclavicular joint, shoulder-hand syndrome, contracture of joint, mistake-use syndrome and abnormal motor mode.ConclusionThe cluster needling of scalp point combined with rehabilitation can improve the patients' living quality effectively.