1.
Protein Pept Lett
; 17(4): 416-8, 2010 Apr.
Artigo
em Inglês
| MEDLINE
| ID: mdl-19594430
RESUMO
To investigate the processing of transforming growth factor beta1 (TGFbeta1) pro-protein by furin protease we expressed a GST-pro-TGFbeta1 fusion protein in bacteria. Analysis of the furin digestion pattern revealed the liberation of 12.5 kDa TGFbeta1 monomers. There was no evidence for cleavage of an alternative furin site within the pro-protein.