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1.
Sci Rep ; 14(1): 14963, 2024 06 28.
Artigo em Inglês | MEDLINE | ID: mdl-38942803

RESUMO

Correctional workers (CWs) report high levels of work stressors, frequent exposures to potentially psychologically traumatic events (PPTEs), and substantial mental health challenges. There is evidence of associations between sleep disturbances and diverse mental health challenges, including preliminary evidence from public safety personnel; however, replications and extensions would better inform interventions to support mental health. The current study was designed to examine associations between quality of sleep, work stress, and mental health disorders in a sample of diverse CWs employed in a provincial correctional service in Ontario, Canada. Data were analyzed from 943 CWs who participated in the cross-sectional, web-based Ontario Provincial Correctional Worker Mental Health and Well-Being Study conducted from December 2017 to June 2018. Sleep quality indicators included symptoms of insomnia, total hours of sleep per night on work nights and off-shift nights, number of days feeling rested per week, and overall sleep quality. Descriptive statistics, analyses of variance, correlational analyses, and logistic regression were used to examine relationships among sleep quality, stress of shift work, and mental health disorder symptoms. CWs slept an average of 6.0 h per night when working and 7.2 h during off-shift nights. CWs reported waking up feeling rested an average of 2.6 days per week and rated their overall quality of sleep in the fair to poor range. Many CWs (64.9%) screened positive for clinically significant symptoms of insomnia. There were also differences across occupational groups such that CWs working as correctional officers reported the most sleep problems. There were statistically significant relationships between insomnia and mental health disorder symptoms. Higher levels of stress from shift work were associated with worse sleep quality. CWs, especially those working as correctional officers in a provincial prison, reported many indicators consistent with poorer quality of sleep. Poor quality of sleep was also associated with work stress and mental health disorders.


Assuntos
Transtornos Mentais , Humanos , Ontário/epidemiologia , Masculino , Adulto , Feminino , Transtornos Mentais/epidemiologia , Pessoa de Meia-Idade , Estudos Transversais , Qualidade do Sono , Estresse Ocupacional/epidemiologia , Prisões , Distúrbios do Início e da Manutenção do Sono/epidemiologia , Saúde Mental , Adulto Jovem , Servidores Penitenciários
2.
Heliyon ; 10(9): e30213, 2024 May 15.
Artigo em Inglês | MEDLINE | ID: mdl-38694021

RESUMO

COVID-19 and the subsequent public health responses disrupted the routines and lives of people globally. The impact was felt by correctional workers who navigated rapidly changing public health policies and many disruptions to operations within both institutional and community correctional services. In the current study, we unpack qualitative findings emerging from an online mental health and well-being survey, during COVID-19, of 571 correctional workers employed in the Canadian province of Alberta. Results emphasize how correctional work was strained by the on-set of the COVID-19 pandemic, creating other risks and vulnerabilities for both staff and incarcerated people. Respondents highlighted impacts to their workload, routine, personal and institutional security, relationships with colleagues and incarcerated people, and their competing perspectives on the enforcement and ethics of ensuing public health measures intended to contain the spread of the virus. We discuss the empirical implications of these findings and areas for future research post pandemic.

3.
Front Psychol ; 15: 1258944, 2024.
Artigo em Inglês | MEDLINE | ID: mdl-38323157

RESUMO

Introduction: The inherent nature of work in correctional services can have negative effects on correctional worker mental health and well-being. Methods: The current study, a replication, analyzes survey data collected from provincial and territorial correctional workers staffed in six regions across Canada (n = 192). Specifically, participants were asked at the end of an extensive mental health and well-being survey an open-ended question requesting any additional feedback or information. Results: Four predominant themes were identified in the data: (1) stigma pertaining to a need to recognize mental health concerns within correctional services; (2) the idea that correctional services wear on the mind and body; (3) a need for better relationships with and support from correctional supervisors, upper management, and ministerial leadership; and (4) suggestions to improve correctional services to help the sector realize its full potential and maximize workplace health. Discussion: We discuss the implications of these findings, with an emphasis on finding ways to promote positive organizational and cultural change in correctional services.

4.
Health Justice ; 11(1): 2, 2023 Jan 23.
Artigo em Inglês | MEDLINE | ID: mdl-36683119

RESUMO

BACKGROUND: Mental health frameworks, best practices, and the well-being of public safety personnel in Canada are topics of increasing interest to both researchers and organizations. To protect and improve worker mental health, different training programs have been implemented to serve this population. The Road to Mental Readiness (R2MR) training regimen is one such program specialized to build cultural awareness of mental health, reduce stigma, and mitigate the cumulative impacts of exposures to potentially psychologically traumatic events among public safety personnel. However, limited research has been conducted to evaluate the effectiveness of R2MR, especially among correctional workers. METHODS: The current study analyzed 307 open-ended survey responses to four (4) questions about R2MR garnered from 124 Canadian provincial and territorial correctional workers between 2018-2020 to reveal their understandings and perceptions of R2MR training, and to identify what learned skills they found challenging or easy to implement. RESULTS: The results suggest that R2MR training plays a significant role in decreasing stigma and increasing mental health awareness. Across jurisdictions, R2MR creates a supportive space for open dialogue around mental health meant to shift cultural and individual barriers that often hinder treatment-seeking. Some respondents also indicated that R2MR was a starting point for intervention. CONCLUSIONS: Further research is necessary to understand how R2MR and other programs could support the mental health and well-being of correctional workers.

5.
Sociol Health Illn ; 44(9): 1500-1516, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-35983895

RESUMO

Research indicates that, relative to the general public and most other types of public safety personnel, correctional workers are more likely to engage in suicide ideation, planning, and attempts. Yet, less is known about lived experiences towards, of, and beyond suicidality among correctional staff. To contribute to this gap in knowledge, the current study draws on qualitative, open-ended survey response data (n = 94) to explore how Canadian provincial correctional workers navigate experiences of suicide, with a focus on the individual, personal, and social factors tied to experiences towards and of suicide thoughts and behaviours. By engaging the seminal works of Foucault, Zizek, and Deleuze and Guattari, we explore respondents' distinct forms of agency when grappling with, challenging, and transcending thoughts around suicide. We then discuss the research implications, with an emphasis on providing correctional workers with confidential, non-stigmatised well-being and treatment-seeking resources and processes, and more health care funding to fully cover timely and sufficient mental health treatment, prevention, and intervention.


Assuntos
Ideação Suicida , Humanos , Canadá , Inquéritos e Questionários
7.
Artigo em Inglês | MEDLINE | ID: mdl-35162485

RESUMO

AIMS: We explore social and relational dynamics tied to an unexplored potentially psychologically traumatic event (PPTE) that can impact nurses' well-being and sense of their occupational responsibilities: namely, the moral, ethical, or professional dilemmas encountered in their occupational work. DESIGN: We used a semi-constructed grounded theory approach to reveal prevalent emergent themes from the qualitative, open-ended component of our survey response data as part of a larger mixed-methods study. METHODS: We administered a national Canadian survey on nurses' experiences of occupational stressors and their health and well-being between May and September 2019. In the current study, we analyzed data from four open text fields in the PPTE section of the survey. RESULTS: In total, at least 109 participants noted that their most impactful PPTE exposure was a moral, professional, and/or ethical dilemma. These participants volunteered the theme as a spontaneous addition to the list of possible PPTE exposures. CONCLUSIONS: Emergent theme analytic results suggest that physicians, other nurses, staff, and/or the decision-making power of patients' families can reduce or eliminate a nurse's perception of their agency, which directly and negatively impacts their well-being and may cause them to experience moral injury. Nurses also report struggling when left to operationalize patient care instructions with which they disagree. IMPACT: Nurses are exposed to PPTEs at work, but little is known about factors that can aggravate PPTE exposure in the field, impact the mental wellness of nurses, and even shape patient care. We discuss the implications of PPTE involving moral, professional, and ethical dilemmas (i.e., potentially morally injurious events), and provide recommendations for nursing policy and practice.


Assuntos
Enfermeiras e Enfermeiros , Transtornos de Estresse Pós-Traumáticos , Canadá , Humanos , Princípios Morais , Inquéritos e Questionários
8.
J Interpers Violence ; 37(11-12): NP10093-NP10125, 2022 06.
Artigo em Inglês | MEDLINE | ID: mdl-33435796

RESUMO

Research on youth sexual offending has focused primarily on its prevalence, risk factors, treatment interventions, and recidivism rates. Thus, there is a need to develop better understandings of the processes towards reconciliation (or the lack thereof) that occur in the context of the collateral consequences of such harm-generating behavior. This qualitative study presents parents' perspectives on the benefits and challenges associated with the implications and outcomes of reconciliation, and of its deprivation among sexually offending youth, victims and their relatives. We analysed in-depth, semi-structured interview data among 16 parents from 10 families in Canada using thematic coding procedures. The findings reveal that in the absence of reconciliation, both relationship repair and rehabilitation are hindered by miscommunication, bitterness, and confusion. By contrast, when meaningful reconciliation occurs, offending youth are better able to take responsibility for their actions, which in many cases led to victim validation and relationship restoration among all affected parties, including immediate and extended relatives. Our research points to the importance of restorative practices in both formal and informal attempts towards accountability, reconciliation, rehabilitation, victim redress, as well as family and community reintegration.


Assuntos
Abuso Sexual na Infância , Adolescente , Criança , Humanos , Pais , Fatores de Risco , Comportamento Sexual , Responsabilidade Social
9.
J Interpers Violence ; 37(21-22): NP19491-NP19521, 2022 11.
Artigo em Inglês | MEDLINE | ID: mdl-34490799

RESUMO

When a youth sexually offends, most of the reactions and repercussions that follow are understandably negative. However, there is limited research about mixed reactions involving remorse and responsibility on the part of the adolescent who offended and their relatives. Based on qualitative interviews with 16 caregivers among 10 families in Canada, this article presents the parents' perspectives on the various processes, benefits, challenges, and outcomes related to expressions of remorse and experiences of responsibility among youth who sexually offended, their victims, and their parents. This study sheds particular light on how adolescent perpetrators of sexual harm and especially their caregivers do feel deeply remorseful and responsible for the impacts of sexual offending behavior, which is contrary to public scrutiny that negatively projects responsibility onto youth offenders and their parents. Thus, our findings emphasize the constructive and considerate ways in which remorse is felt and responsibility is assumed; and by extension, they point to the importance of restorative practices in efforts toward reconciliation and accountability.


Assuntos
Abuso Sexual na Infância , Adolescente , Cuidadores , Criança , Emoções , Humanos , Pais , Comportamento Sexual
10.
Front Psychol ; 13: 1026821, 2022.
Artigo em Inglês | MEDLINE | ID: mdl-36687848

RESUMO

Public safety personnel are at an elevated risk for suicidal thoughts and behaviors relative to the general public. Correctional workers in particular report some of the highest prevalence of suicidal thoughts and behaviors. To better understand this phenomenon, the current study draws on qualitative, open-ended survey response data (n = 94) that explores three distinct themes (occupational environment, lack of support, social silence) and how entrenched notions of mental health stigma and occupational culture inform how Canadian correctional workers understand their experiences with suicidal thoughts and behaviors. We conclude with a brief discussion of the research and policy implications, with an emphasis on mobilizing efforts to normalize mental health discussion in correctional workplaces, bolstering peer support resources, and collaboration, and assessing the limited organizational supports available to struggling staff.

11.
PLoS One ; 16(12): e0252929, 2021.
Artigo em Inglês | MEDLINE | ID: mdl-34914724

RESUMO

Foot health in zoo giraffe has been a topic of recent research, although little is known about the foot health of free-ranging giraffe. This study describes the foot shape and radiographic pathological changes in 27 young adult Nubian giraffe (Giraffa camelopardalis camelopardalis) from a translocation in Uganda (August 2017). Giraffe feet were observed to have a concave sole, the hoof wall was longest by the toe tip, and the weight-bearing surface of the foot was primarily along the periphery of the foot including hoof wall, parts of the heel, and the edge of the sole. Radiographs showed that pedal osteitis and sesamoid bone cysts were relatively uncommon (3/24 giraffe with osteitis, 1/24 giraffe with sesamoid cysts), and that no giraffe in the study had P3 joint osteoarthritis, P3 rotation, or P3 fractures. Radiographs consistently demonstrated a positive palmar/plantar angle with the sole of the hoof thicker at the heel than by the toe tip, with the non weight-bearing palmar/plantar angle measuring 1.6°- 4.3°. This is the first systematic review of foot shape and radiographs in free-ranging giraffe and demonstrates a low prevalence of foot pathologies. This study suggests qualitative differences in foot shape, foot health, radiographic anatomy, and foot pathologies when comparing free-ranging and zoo giraffe. Further research is needed to identify why these differences occur and whether husbandry modifications could help improve zoo giraffe foot health and prevent associated lameness.


Assuntos
Fraturas Ósseas/diagnóstico por imagem , Girafas , Extremidade Inferior/diagnóstico por imagem , Osteíte/diagnóstico por imagem , Animais , Fraturas Ósseas/veterinária , Casco e Garras , Osteíte/veterinária , Uganda
12.
Comp Med ; 70(1): 45-55, 2020 02 01.
Artigo em Inglês | MEDLINE | ID: mdl-31952557

RESUMO

The guinea pig model of tuberculosis is used extensively to assess the efficacy of novel tuberculosis vaccines. There are established parameters to determine vaccine efficacy in this model, but the science community currently lacks established biomarkers for early detection and monitoring of experimental disease in guinea pigs. To define a set of biomarkers that could be used as benchmarks for disease progression and early endpoint criteria, we assessed serum biochemical and hematology parameters in 2 groups of guinea pigs-one vaccinated with the attenuated Mycobacterium bovis vaccine strain (BCG) and one sham-vaccinated with saline-and then experimentally infected with a virulent strain of Mycobacterium tuberculosis. After infection, WBC showed the strongest differences between saline-inoculated and vaccinated animals, with more subtle changes in other serum biochemical parameters, including ALT and ALP. Therefore, this study provides a starting point for evaluating the utility of blood values as possible early endpoint criteria in the guinea pig model of tuberculosis.


Assuntos
Determinação de Ponto Final/métodos , Cobaias , Vacinas contra a Tuberculose/imunologia , Animais , Biomarcadores/sangue , Modelos Animais de Doenças , Progressão da Doença , Feminino , Mycobacterium tuberculosis/imunologia
13.
J Vet Diagn Invest ; 32(1): 118-123, 2020 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-31735118

RESUMO

In the United States, ~1.4 million sporadic human Salmonella enterica infections occur annually, with an estimated 6% attributable to reptile exposure. Detection of Salmonella in reptiles can be challenging given the limitations among detection methods. We evaluated sampling and detection methods for S. enterica in a cross-sectional study of reptilian patients (n = 45) over the course of 13 mo. Two sampling methods (cloacal swabs, electrostatic cloth body-feet samples) and 3 detection methods (enriched culture, lateral flow immunoassay [LFI], real-time PCR) were compared using McNemar and Fisher exact tests. Results varied by species, sample type, and detection method. In total, 14 of 45 (33%) patients were positive by culture, 10 of 45 (22%), and/or 13 of 45 (29%) by rtPCR. Among rtPCR-positive results, cloacal swabs (12 of 45 [27%]) resulted in a higher detection than body-feet wipes (4 of 45 [9%]; p = 0.01). Among culture-positive results, shedding was most commonly detected after additional incubation at room temperature when testing cloacal swabs (9 of 45 [20%]). However, there was significant disagreement between sampling methods (cloacal vs. body-feet; p = 0.03). No samples were positive by LFI. In general, cloacal swabs yielded the highest test-positive rates, irrespective of testing method. Our study highlights the importance of using detection methods optimized for the sample being tested.


Assuntos
Derrame de Bactérias , Répteis/microbiologia , Salmonelose Animal/microbiologia , Salmonella enterica/fisiologia , Animais , Estudos Transversais , Fezes/microbiologia , Hospitais de Ensino , Reação em Cadeia da Polimerase em Tempo Real/veterinária , Salmonelose Animal/diagnóstico
14.
Vet Ophthalmol ; 22(6): 834-841, 2019 Nov.
Artigo em Inglês | MEDLINE | ID: mdl-30938083

RESUMO

OBJECTIVE: Iridocorneal angle (ICA) narrowing is a known risk factor for primary glaucoma in multiple species, but has not been described in companion rabbits. This study aimed to develop an ICA grading scheme for companion rabbits to enable early glaucoma predisposition diagnosis. ANIMALS STUDIED: Twenty healthy rabbits of varying breeds and ages. PROCEDURES: Rabbits received complete ophthalmic examinations, including gonioscopy, and imaging of the ICA using spectral-domain optical coherence tomography (SD-OCT), Scheimpflug imaging (Pentacam® HR), and high-resolution ultrasound (HRUS). Angle opening distance (AOD) and angle recess area (ARA) of the ICA were measured and assessed for agreement using a Bland-Altman analysis. A five-stage gonioscopy grading scheme was created, and Spearman-rank test assessed for correlation between gonioscopy grades and ICA measurements. Differences among age and sex were analyzed with a nonparametric ANOVA and Wilcoxon rank-sum test, respectively. RESULTS: Analysis revealed AOD medians of 0.28mm for SD-OCT [95% CI: 0.24-0.31], 0.20mm for Pentacam® HR [95% CI: 0.18-0.21], and 0.25mm for HRUS [95% CI: 0.22-0.28]. The median ARA was 0.14mm2 for SD-OCT [95% CI: 0.117-0.163], 0.09mm2 for Pentacam® HR [95% CI: 0.082-0.100], and 0.06mm2 for HRUS [95% CI: 0.046-0.054]. The association between gonioscopy grade and SD-OCT ARA was significant (P < 0.05), and there was a significant difference (P < 0.001) between imaging modalities for both ARA and AOD. CONCLUSIONS: Gonioscopy grade correlated well with SD-OCT ARA. Therefore, SD-OCT is recommended as a noncontact method for evaluating companion rabbit ICA. Each imaging device should not be used interchangeably for ICA evaluation.


Assuntos
Glaucoma de Ângulo Fechado/veterinária , Gonioscopia/veterinária , Tomografia de Coerência Óptica/veterinária , Animais , Feminino , Glaucoma de Ângulo Fechado/diagnóstico , Glaucoma de Ângulo Fechado/patologia , Masculino , Coelhos , Tomografia de Coerência Óptica/métodos , Ultrassonografia/métodos , Ultrassonografia/veterinária
15.
J Zoo Wildl Med ; 50(3): 528-538, 2019 Sep.
Artigo em Inglês | MEDLINE | ID: mdl-33517621

RESUMO

Front foot radiographs from 22 giraffe (Giraffa camelopardalis reticulata) at one zoo were analyzed to better understand causes of lameness in this giraffe population. The herd had a history of front hoof overgrowth and intermittent lameness. Radiographic findings included distal interphalangeal joint osteoarthritis (OA), distal phalangeal bone (P3) osteitis, P3 fractures, P3 rotation, and sesamoid bone cysts. OA of the distal interphalangeal joint occurred in at least one front foot of 73% (16/22 giraffe) of the herd, and all giraffe had OA by 7 yr of age. Pedal osteitis was present in at least one front foot in 86% (19/22) of the giraffe, starting in animals as young as 1 yr old. P3 fractures were present in 36% (8/22) of the herd. These fractures were near the site of the deep digital flexor attachment and were diagnosed in giraffe as young as 10 yr old. The presence of severe osteitis was associated with the presence of P3 fractures. This study is unique in that a large herd was trained to participate in voluntary front foot radiographs so multiple causes of foot disease could be diagnosed antemortem and without anesthesia. Although the underlying causes of these lesions are likely multifactorial and currently unknown to us, the high prevalence of foot disease in relatively young animals warrants further investigation across zoos. In this study, OA, osteitis, and P3 fractures were common radiographic findings among giraffe that were limping. Subsequent monitoring and management changes suggest that proactive management of foot health can decrease morbidity and mortality in zoo giraffe.


Assuntos
Doenças do Pé/veterinária , Girafas , Envelhecimento , Animais , Animais de Zoológico , Doenças do Pé/diagnóstico por imagem , Fraturas Ósseas/diagnóstico por imagem , Fraturas Ósseas/veterinária , Osteíte/diagnóstico por imagem , Osteíte/veterinária
16.
Can Rev Sociol ; 55(2): 278-297, 2018 May.
Artigo em Inglês | MEDLINE | ID: mdl-29633567

RESUMO

This qualitative content analysis of 723 anonymous reviews of 60 Canadian food service employers, posted on RateMyEmployer.ca, explores how digital spaces publically circulate precarious workers' resistances and management of occupational stigma. We introduce to literature on "dirty work" the concept of socioeconomic hygiene, which identifies a particular kind of social and moral order within which the positions of the subordinated are naturalized between the socially and morally "clean" and "unclean."

17.
J Zoo Wildl Med ; 48(2): 540-543, 2017 Jun.
Artigo em Inglês | MEDLINE | ID: mdl-28749298

RESUMO

An 18-yr-old female Western lowland gorilla ( Gorilla gorilla gorilla) presented with acute-onset severe lethargy, bloody vaginal discharge, decreased appetite, and an abnormal posture. The gorilla was diagnosed with a ruptured cecal blind sac with severe adhesions to the right ovary. A typhlectomy and unilateral ovariectomy were performed. Histologic examination identified a severe transmural circumferential typhlitis with rupture and adhesions to the infundibulum and chronic typhlitis. Postoperative management included antibiotics, analgesics, short-term dietary modifications, and probiotics for suspect oral candidiasis. The gorilla made a full clinical recovery and was pregnant within 1 yr of surgery. To the authors' knowledge, this is the first case of successful management of typhlitis in a gorilla. Typhlitis and intestinal rupture should be considered as a differential diagnosis for acute onset severe abdominal pain in gorillas.


Assuntos
Doenças dos Símios Antropoides/patologia , Ceco/lesões , Gorilla gorilla , Perfuração Intestinal/veterinária , Peritonite/veterinária , Animais , Doenças dos Símios Antropoides/terapia , Ceco/patologia , Feminino , Perfuração Intestinal/cirurgia , Peritonite/etiologia , Peritonite/microbiologia , Peritonite/terapia , Infecções Estreptocócicas/microbiologia , Infecções Estreptocócicas/veterinária
18.
J Avian Med Surg ; 31(1): 39-46, 2017 Mar.
Artigo em Inglês | MEDLINE | ID: mdl-28358607

RESUMO

An adult male blue and gold macaw (Ara ararauna) was presented for evaluation of a right periorbital mass. Results of diagnostic tests, including periorbital ultrasound, fine-needle aspirate, and cytologic examination, confirmed a diagnosis of periocular lymphoma. Radiographs were suggestive of disseminated disease but because of concerns about the patient's quality of life, localized radiation therapy to address the periorbital disease was pursued. Coarse-fractionated radiation therapy was initiated, and the mass regressed rapidly during the 3-week course of treatment. The macaw tolerated the treatments well, maintained vision in the affected eye, and activity level and appetite improved. Three months after treatment was completed, the bird died. Necropsy revealed T-cell-rich B-cell-infiltrative lymphoma of the spleen, liver, and kidneys, with some residual neoplastic cells found in the right periorbital region. This case demonstrates a radiation therapy protocol that reduced a tumor mass in a localized treatment of periorbital lymphoma in a macaw.


Assuntos
Doenças das Aves/radioterapia , Neoplasias Oculares/veterinária , Linfoma/veterinária , Psittaciformes , Animais , Neoplasias Oculares/radioterapia , Linfoma/radioterapia , Masculino
19.
Am J Vet Res ; 77(5): 540-7, 2016 May.
Artigo em Inglês | MEDLINE | ID: mdl-27111022

RESUMO

OBJECTIVE To determine whether extent of collateral circulation would change during temporary occlusion of the caudal vena cava (CVC) in ferrets (Mustela putorius), a pressure change would occur caudal to the occlusion, and differences would exist between the sexes with respect to those changes. ANIMALS 8 adult ferrets (4 castrated males and 4 spayed females). PROCEDURES Ferrets were anesthetized. A balloon occlusion catheter was introduced through a jugular vein, passed into the CVC by use of fluoroscopy, positioned cranial to the right renal vein, and inflated for 20 minutes. Venography was performed 5 and 15 minutes after occlusion. Pressure in the CVC caudal to the occlusion was measured continuously. A CBC, plasma biochemical analysis, and urinalysis were performed immediately after the procedure and 2 or 3 days later. RESULTS All 8 ferrets survived the procedure; no differences were apparent between the sexes. Vessels providing collateral circulation were identified in all ferrets, indicating blood flow to the paravertebral venous plexus. Complications observed prior to occlusion included atrial and ventricular premature contractions. Complications after occlusion included bradycardia, seizures, and extravasation of contrast medium. Mean baseline CVC pressure was 5.4 cm H2O. During occlusion, 6 ferrets had a moderate increase in CVC pressure (mean, 24.3 cm H2O) and 2 ferrets had a marked increase in CVC pressure to > 55.0 cm H2O. CONCLUSIONS AND CLINICAL RELEVANCE Caval occlusion for 20 minutes was performed in healthy ferrets with minimal adverse effects noted within the follow-up period and no apparent differences between sexes. The CVC pressure during occlusion may be prognostic in ferrets undergoing surgical ligation of the CVC, which commonly occurs during adrenal tumor resection.


Assuntos
Circulação Colateral , Furões , Veia Cava Inferior/fisiopatologia , Hiperfunção Adrenocortical/cirurgia , Hiperfunção Adrenocortical/veterinária , Animais , Oclusão com Balão/veterinária , Feminino , Masculino , Veia Cava Inferior/cirurgia
20.
Lab Anim (NY) ; 45(1): 35-41, 2016 Jan.
Artigo em Inglês | MEDLINE | ID: mdl-26684957

RESUMO

The guinea pig is a common animal model that is used in biomedical research to study a variety of systems, including hormonal and immunological responses, pulmonary physiology, corticosteroid response and others. However, because guinea pigs are evolutionarily a prey species, they do not readily show behavioral signs of disease, which can make it difficult to detect illness in a laboratory setting. Minimally invasive blood tests, such as complete blood counts and plasma biochemistry assays, are useful in both human and veterinary medicine as an initial diagnostic technique to rule in or rule out systemic illness. In guinea pigs, phlebotomy for such tests often requires that the animals be anesthetized first. The authors evaluated hematological and plasma biochemical effects of two anesthetic agents that are commonly used with guinea pigs in a research setting: isoflurane and a combination of ketamine and xylazine. Hematological and plasma biochemical parameters were significantly different when guinea pigs were under either anesthetic, compared to when they were unanesthetized. Plasma proteins, liver enzymes, white blood cells and red blood cells appeared to be significantly altered by both anesthetics, and hematological and plasma biochemical differences were greater when guinea pigs were anesthetized with the combination of ketamine and xylazine than when they were anesthetized with isoflurane. Overall these results indicate that both anesthetics can significantly influence hematological and plasma biochemical parameters in guinea pigs.


Assuntos
Anestésicos/farmacologia , Análise Química do Sangue/veterinária , Cobaias/sangue , Isoflurano/farmacologia , Ketamina/farmacologia , Xilazina/farmacologia , Anestésicos Combinados/farmacologia , Animais , Animais de Laboratório , Contagem de Células Sanguíneas/veterinária , Feminino , Fígado/enzimologia
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