1.
J Extra Corpor Technol
; 37(3): 319-23; discussion 318, 2005 Sep.
Artigo
em Inglês
| MEDLINE
| ID: mdl-16350389
Assuntos
Ponte Cardiopulmonar/história , Terapia com Hirudina/história , Proteínas Recombinantes/uso terapêutico , Ponte Cardiopulmonar/efeitos adversos , Tratamento de Emergência , Heparina/efeitos adversos , História do Século XX , Humanos , Masculino , Pessoa de Meia-Idade , Tempo de Tromboplastina Parcial , Trombocitopenia/induzido quimicamente , Trombocitopenia/prevenção & controle
2.
J Extra Corpor Technol
; 34(4): 281-4, 2002 Dec.
Artigo
em Inglês
| MEDLINE
| ID: mdl-12533066
RESUMO
This case report addresses the use of Argatroban, an anticoagulant and thrombin inhibitor for treatment of thrombocytopenia in an adult patient on extracorporeal membrane oxygenation (ECMO). After 5 days on ECMO, the patient showed signs of heparin-induced thrombocytopenia (HIT) with a platelet count of 20K. Argatroban was initiated to decrease progression of HIT and continue treatment with ECMO proved to be successful. Given the occurrence of HIT with heparin therapy, a need for alternate drug therapy is required for patients requiring treatment with ECMO. The use of Argatroban in adult ECMO is outlined and includes dosage, monitoring, and patient treatment.