1.
Org Biomol Chem
; 14(24): 5774-8, 2016 Jun 15.
Artigo
em Inglês
| MEDLINE
| ID: mdl-27005847
RESUMO
A mild and selective new method was discovered to reduce acetanilides and other carbonyl compounds. Unlike sodium borohydride, which is selective in reducing aldehydes and ketones, this new protocol is uniquely selective in reducing acetanilides and nitriles over other carbonyl containing functional groups. Additionally, ß-ketoamides were shown to be reduced at the ketone preferentially over the amide.