Mortui vivos docent--the dead teach the living: 18-flurodeoxyglocose positron emission tomography-computed tomography findings in a case of intravascular B cell lymphoma.

Intravascular large B-cell lymphoma is a rare and aggressive variant of diffuse large B-cell non-Hodgkin's lymphoma. Its atypical presentation often delays the diagnosis and due to its aggressive behavior, the diagnosis is made post-mortem in half of the cases. We present FDG PET/CT findings in a case of IVLCL. In our case, the report of the patient's bone marrow biopsy after death of the patient revealed the presence of IVLCL. After availability of final diagnosis, we reviewed the literature and a better explanation of the FDG PET/CT findings could be obtained. We describe this case, to call for heightened awareness in physicians for the rare but possible diagnosis of IVCLL, particularly in an elderly patient who presents with fever of unknown origin and demonstrates similar FDG PET/CT findings. Considering the characteristic scan findings described in our patient and other cases in literature, FDG PET/CT can be used in suspected cases of IVLCL for early diagnosis of this rapidly fatal malignancy.

Malignant amelanotic melanoma--a diagnostic surprise: Flurodeoxyglocose Positron Emission Tomography-Computed Tomography and immunohistochemistry clinch the 'final diagnosis'.

Amelanotic melanoma is a rare malignancy and the prognosis is usually poorer than that of pigmented melanomas, because of delay in establishing the correct diagnosis, and in treatment initiation. In our case report, we present a the Flurodeoxyglocose Positron Emission Tomography-Computed Tomography (FDG PET/CT) findings of a patient suffering from malignant amelanotic melanoma and its histopathological confirmation and immunohistochemistry (IHC) correlation In the described case, amelanotic melanoma masqueraded as adenocarcinoma of the rectum in the pathology as well the clinical course. Our case highlights the importance of obtaining a tissue diagnosis and IHC confirmation whenever unusual PET/CT findings are encountered.

F-18 flourodeoxyglucose positron emission tomography/computed tomography findings in a case of hepatosplenic T-cell lymphoma.

T-cell lymphoma (TCL) is a biologically diverse and uncommon group of lymphoid malignant diseases. Compared with its B-cell counterparts, TCL is notably more difficult to diagnose and manage owing to its rarity and biologic heterogeneity. Hepatosplenic TCL is an extremely rare subtype of TCL. A 37-year-old Indian male presented to his physician with swelling and pain in left hypochondrium. Clinical examination revealed pallor, icterus and massive splenomegaly. His blood examination revealed pancytopenia. His bone marrow biopsy was suggestive of lymphoma. Whole body F-18 flourodeoxyglucose positron emission tomography/computed tomography (FDG PET/CT) scan revealed diffuse increased metabolic activity in massively enlarged spleen, liver and bone marrow. There was no evidence of metabolically active lymphadenopathy anywhere in the body. Guided by the FDG PET/CT findings, a liver biopsy was advised. Liver histopathology revealed the presence of hepatosplenic TCL. A final diagnosis of hepatosplenic TCL with liver, spleen and bone marrow involvement was made. Even though rare, hepatosplenic TCL should be considered as a possible diagnosis in patients presenting with similar clinical picture and FDG PET/CT scan findings.